Publications by authors named "Timothy Jensen"

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Implications for cystic fibrosis therapy: Potentiator icenticaftor is superior to ivacaftor in improving function and maintaining stability of F508del CFTR.
Deborah M Cholon, Luba A Aleksandrov, Nancy L Quinney, Susan E Boyles, Timothy J Jensen

Sci Prog· October 2025

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Conformational Variability in Ground-State CFTR Lipoprotein Particle Cryo-EM Ensembles.
Luba A Aleksandrov, Adrei A Aleksandrov, Timothy J Jensen, Joshua D Strauss, Jonathan F Fay

Int J Mol Sci· August 2022

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Rapid Detection of Direct Compound Toxicity and Trailing Detection of Indirect Cell Metabolite Toxicity in a 96-Well Fluidic Culture Device for Cell-Based Screening Environments: Tactics in Six Sigma Quality Control Charts.
Bob Lubamba, Timothy Jensen, Randall McClelland

Appl Sci (Basel)· March 2022

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A Unidirectional 96-Well Fluidic Culture Platform for Upstream Cell Dosing with Subsequent Downstream Nonlinear and Ascending Exposure Gradients for Real-Time and Cell-Based Toxicity Screening Environments.
Bincy A John, David J Sloan, Timothy C Jensen, Sreenivasa C Ramaiahgari, Peter End

Appl In Vitro Toxicol· December 2021

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Personalised medicine for non-classic cystic fibrosis resulting from rare CFTR mutations.
Matthew S McCravy, Nancy L Quinney, Deborah M Cholon, Susan E Boyles, Timothy J Jensen

Eur Respir J· July 2020

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Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel.
Jonathan F Fay, Luba A Aleksandrov, Timothy J Jensen, Liying L Cui, Joseph N Kousouros

Biochemistry· October 2018

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Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator.
Amandeep K Gakhal, Timothy J Jensen, Zoltan Bozoky, Ariel Roldan, Gergely L Lukacs

MAbs· December 2017

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The cubicon method for concentrating membrane proteins in the cubic mesophase.
Pikyee Ma, Dietmar Weichert, Luba A Aleksandrov, Timothy J Jensen, John R Riordan

Nat Protoc· September 2017

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Potential sites of CFTR activation by tyrosine kinases.
Arnaud Billet, Yanlin Jia, Timothy J Jensen, Yue-Xian Hou, Xiu-Bao Chang

Channels (Austin)· December 2016

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Thermal stability of purified and reconstituted CFTR in a locked open channel conformation.
Luba A Aleksandrov, Timothy J Jensen, Liying Cui, Joseph N Kousouros, Lihua He

Protein Expr Purif· December 2015

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The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore.
David G Washburn, Dennis A Holt, Jason Dodson, Jeff J McAtee, Lamont R Terrell, Timothy C Jensen

Bioorg Med Chem Lett· September 2013

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Syntheses, properties and cellular studies of metalloisoporphyrins.
Sandra C Mwakwari, Haijun Wang, Timothy J Jensen, M Graça H Vicente, Kevin M Smith

J Porphyr Phthalocyanines· September 2011

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Restoration of domain folding and interdomain assembly by second-site suppressors of the DeltaF508 mutation in CFTR.
Lihua He, Luba A Aleksandrov, Liying Cui, Timothy J Jensen, Kenneth L Nesbitt

FASEB J· August 2010

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Effect of overall charge and charge distribution on cellular uptake, distribution and phototoxicity of cationic porphyrins in HEp2 cells.
Timothy J Jensen, M Graça H Vicente, Raymond Luguya, Jolanna Norton, Frank R Fronczek

J Photochem Photobiol B· August 2010

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Influence of the number and distribution of NLS peptides on the photosensitizing activity of multimeric porphyrin-NLS.
Martha Sibrian-Vazquez, Timothy J Jensen, M Graça H Vicente

Org Biomol Chem· March 2010

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Role of individual R domain phosphorylation sites in CFTR regulation by protein kinase A.
Tamás Hegedus, Andrei Aleksandrov, April Mengos, Liying Cui, Timothy J Jensen

Biochim Biophys Acta· June 2009

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Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator.
Xiu-Bao Chang, April Mengos, Yue-Xian Hou, Liying Cui, Timothy J Jensen

J Cell Sci· September 2008

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Seminaphthofluorones are a family of water-soluble, low molecular weight, NIR-emitting fluorophores.
Youjun Yang, Mark Lowry, Xiangyang Xu, Jorge O Escobedo, Martha Sibrian-Vazquez, Timothy J Jensen

Proc Natl Acad Sci U S A· July 2008

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Synthesis, characterization, and metabolic stability of porphyrin-peptide conjugates bearing bifunctional signaling sequences.
Martha Sibrian-Vazquez, Timothy J Jensen, M Graça H Vicente

J Med Chem· May 2008

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Synthesis and in vitro properties of trimethylamine- and phosphonate-substituted carboranylporphyrins for application in BNCT.
Michael W Easson, Frank R Fronczek, Timothy J Jensen, M Graça H Vicente

Bioorg Med Chem· March 2008

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Mitochondria targeting by guanidine- and biguanidine-porphyrin photosensitizers.
Martha Sibrian-Vazquez, Irina V Nesterova, Timothy J Jensen, M Graça H Vicente

Bioconjug Chem· March 2008

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Syntheses and properties of a series of cationic water-soluble phthalocyanines.
Hairong Li, Timothy J Jensen, Frank R Fronczek, M Graça H Vicente

J Med Chem· February 2008

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Porphyrin-retinamides: synthesis and cellular studies.
Martha Sibrian-Vazquez, Timothy J Jensen, M Graça H Vicente

Bioconjug Chem· October 2007

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Synthesis and cellular studies of PEG-functionalized meso-tetraphenylporphyrins.
Martha Sibrian-Vazquez, Timothy J Jensen, M Graça H Vicente

J Photochem Photobiol B· January 2007

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An organic white light-emitting fluorophore.
Youjun Yang, Mark Lowry, Corin M Schowalter, Sayo O Fakayode, Jorge O Escobedo, Timothy J Jensen

J Am Chem Soc· November 2006

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