Publications by authors named "Timothy Johanssen"

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Targeting NKG2D ligands in glioblastoma with a bispecific T-cell engager is augmented with conventional therapy and enhances oncolytic virotherapy of glioma stem-like cells.
Richard Baugh, Hena Khalique, Emma Page, Janet Lei-Rossmann, Peter Kok-Ting Wan, Timothy Johanssen

J Immunother Cancer· May 2024

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Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells.
Paschalis Athanasiadis, Balaguru Ravikumar, Richard J R Elliott, John C Dawson, Neil O Carragher, Timothy Johanssen

iScience· July 2023

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Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia.
Timothy Johanssen, Laura McVeigh, Sara Erridge, Geoffrey Higgins, Joelle Straehla

Front Oncol· January 2023

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Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons.
Adam P Gunn, Bruce X Wong, Timothy Johanssen, James C Griffith, Colin L Masters

J Biol Chem· March 2016

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PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning.
Timothy Johanssen, Nuttawat Suphantarida, Paul S Donnelly, Xiang M Liu, Steven Petrou

Neurobiol Dis· September 2015

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C-terminal peptides modelling constitutive PrPC processing demonstrate ameliorated toxicity predisposition consequent to α-cleavage.
Vanessa A Johanssen, Timothy Johanssen, Colin L Masters, Andrew F Hill, Kevin J Barnham

Biochem J· April 2014

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Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples.
Andrew D Watt, Keyla A Perez, Alan Rembach, Nicki A Sherrat, Lin Wai Hung, Timothy Johanssen

Acta Neuropathol· April 2013

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Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Giuseppe D Ciccotosto, Deborah J Tew, Simon C Drew, Danielle G Smith, Timothy Johanssen

Neurobiol Aging· February 2011

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Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
James A Duce, Andrew Tsatsanis, Michael A Cater, Simon A James, Elysia Robb, Timothy Johanssen

Cell· September 2010

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Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Kevin J Barnham, Vijaya B Kenche, Giuseppe D Ciccotosto, David P Smith, Deborah J Tew, Timothy J Johanssen

Proc Natl Acad Sci U S A· May 2008

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Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.
David P Smith, Giuseppe D Ciccotosto, Deborah J Tew, Michelle T Fodero-Tavoletti, Timothy Johanssen

Biochemistry· March 2007

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