Publications by authors named "Timothy Keane"

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Sprayable extracellular matrix hydrogel reduces postoperative adhesion formation and protects healing tissues in preclinical models.
Lucía Pascual-Antón, Pilar Sandoval, Henar Tomero-Sanz, Michela Terri, Raffaele Strippoli, Timothy J Keane

Sci Transl Med· October 2025

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Editorial: Molecular mechanisms and new therapeutic targets in epithelial to mesenchymal transition (EMT) and fibrosis, volume II.
Cecilia Battistelli, Marc Diederich, Timothy Joseph Keane, Pilar Sandoval, Sergio Valente

Front Pharmacol· September 2022

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The effect of normal, metaplastic, and neoplastic esophageal extracellular matrix upon macrophage activation.
Lindsey T Saldin, Molly Klimak, Ryan C Hill, Madeline C Cramer, Luai Huleihel, Timothy J Keane

J Immunol Regen Med· August 2021

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Neutrophils Enable Local and Non-Invasive Liposome Delivery to Inflamed Skeletal Muscle and Ischemic Heart.
Junyi Che, Adrian Najer, Anna K Blakney, Paul F McKay, Mohamed Bellahcene, Timothy J Keane

Adv Mater· December 2020

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A blueprint for translational regenerative medicine.
James P K Armstrong, Timothy J Keane, Anne C Roques, P Stephen Patrick, Claire M Mooney

Sci Transl Med· December 2020

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In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy.
Håkon Høgset, Conor C Horgan, James P K Armstrong, Mads S Bergholt, Vincenzo Torraca, Timothy J Keane

Nat Commun· December 2020

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Editorial: Molecular Mechanisms and New Therapeutic Targets in Epithelial to Mesenchymal Transition (EMT) and Fibrosis.
Cecilia Battistelli, Marc Diederich, Timothy Joseph Keane, Pilar Sandoval, Sergio Valente

Front Pharmacol· January 2020

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Scarring vs. functional healing: Matrix-based strategies to regulate tissue repair.
Timothy J Keane, Christine-Maria Horejs, Molly M Stevens

Adv Drug Deliv Rev· April 2018

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Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy.
Gregor Fuhrmann, Rona Chandrawati, Paresh A Parmar, Timothy J Keane, Stephanie A Maynard

Adv Mater· April 2018

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Bioscaffold-mediated mucosal remodeling following short-segment colonic mucosal resection.
Jenna L Dziki, Timothy J Keane, Shahab Shaffiey, Dan Cognetti, Neill Turner

J Surg Res· October 2017

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The extracellular matrix of the gastrointestinal tract: a regenerative medicine platform.
George S Hussey, Timothy J Keane, Stephen F Badylak

Nat Rev Gastroenterol Hepatol· September 2017

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Restoring Mucosal Barrier Function and Modifying Macrophage Phenotype with an Extracellular Matrix Hydrogel: Potential Therapy for Ulcerative Colitis.
Timothy J Keane, Jenna Dziki, Eric Sobieski, Adam Smoulder, Arthur Castleton

J Crohns Colitis· March 2017

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The impact of detergents on the tissue decellularization process: A ToF-SIMS study.
Lisa J White, Adam J Taylor, Denver M Faulk, Timothy J Keane, Lindsey T Saldin

Acta Biomater· March 2017

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Preparation and characterization of a biologic scaffold and hydrogel derived from colonic mucosa.
Timothy J Keane, Jenna Dziki, Arthur Castelton, Denver M Faulk, Victoria Messerschmidt

J Biomed Mater Res B Appl Biomater· February 2017

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MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model.
Ali H Zaidi, Lindsey T Saldin, Lori A Kelly, Linda Bergal, Ricardo Londono, Timothy J Keane

PLoS One· March 2016

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The effect of terminal sterilization on the material properties and in vivo remodeling of a porcine dermal biologic scaffold.
Christopher L Dearth, Timothy J Keane, Christopher A Carruthers, Janet E Reing, Luai Huleihel

Acta Biomater· March 2016

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Inhibition of COX1/2 alters the host response and reduces ECM scaffold mediated constructive tissue remodeling in a rodent model of skeletal muscle injury.
Christopher L Dearth, Peter F Slivka, Scott A Stewart, Timothy J Keane, Justin K Tay

Acta Biomater· February 2016

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Intestinal stem cell growth and differentiation on a tubular scaffold with evaluation in small and large animals.
Shahab A Shaffiey, Hongpeng Jia, Timothy Keane, Cait Costello, Deena Wasserman

Regen Med· January 2016

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Composite ECM-alginate microfibers produced by microfluidics as scaffolds with biomineralization potential.
Marco Angelozzi, Martina Miotto, Letizia Penolazzi, Stefania Mazzitelli, Timothy Keane

Mater Sci Eng C Mater Biol Appl· November 2015

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Concentration-dependent rheological properties of ECM hydrogel for intracerebral delivery to a stroke cavity.
Andre R Massensini, Harmanvir Ghuman, Lindsey T Saldin, Christopher J Medberry, Timothy J Keane

Acta Biomater· November 2015

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A Rodent Model to Evaluate the Tissue Response to a Biological Scaffold When Adjacent to a Synthetic Material.
Christopher L Dearth, Timothy J Keane, Jeffrey R Scott, Kerry A Daly, Stephen F Badylak

Tissue Eng Part A· October 2015

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Tissue-Specific Effects of Esophageal Extracellular Matrix.
Timothy J Keane, Aaron DeWard, Ricardo Londono, Lindsey T Saldin, Arthur A Castleton

Tissue Eng Part A· September 2015

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Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance.
Timothy J Keane, Ilea T Swinehart, Stephen F Badylak

Methods· August 2015

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Fragmented local governance and water resource management outcomes.
Jae Hong Kim, Timothy D Keane, Eric A Bernard

J Environ Manage· March 2015

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Biomaterials for tissue engineering applications.
Timothy J Keane, Stephen F Badylak

Semin Pediatr Surg· June 2014

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