Publications by authors named "Timothy Koves"

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The Failing Heart Relies on Ketone Bodies as a Fuel.
Gregory Aubert, Ola J Martin, Julie L Horton, Ling Lai, Rick B Vega, Teresa C Leone, Timothy Koves, Stephen J Gardell, Marcus Krüger, Charles L Hoppel

Circulation· February 2016

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Formation of I+III supercomplex rescues respiratory chain defects.
Chao Liang, Abhilash Padavannil, Shan Zhang, Sheryl Beh, David R L Robinson, Timothy R Koves

Cell Metab· February 2025

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Bioengineered Model of Human LGMD2B Skeletal Muscle Reveals Roles of Intracellular Calcium Overload in Contractile and Metabolic Dysfunction in Dysferlinopathy.
Alastair Khodabukus, Neel K Prabhu, Taylor Roberts, Meghan Buldo, Amber Detwiler, Timothy R Koves

Adv Sci (Weinh)· August 2024

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Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding.
Ashley S Williams, Scott B Crown, Scott P Lyons, Timothy R Koves, Rebecca J Wilson

Cell Metab· February 2024

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Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles.
Timothy R Koves, Guo-Fang Zhang, Michael T Davidson, Alec B Chaves, Scott B Crown

Cell Metab· June 2023

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RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure.
Tsunehisa Yamamoto, Santosh K Maurya, Elizabeth Pruzinsky, Kirill Batmanov, Yang Xiao, Timothy R Koves

J Clin Invest· May 2023

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Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
Adilson Guilherme, Leslie A Rowland, Nicole Wetoska, Emmanouela Tsagkaraki, Kaltinaitis B Santos, Timothy R Koves

Cell Rep· May 2023

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Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism.
Yvo J M Op den Kamp, Anne Gemmink, Marlies de Ligt, Bas Dautzenberg, Esther Kornips, Timothy R Koves

Mol Metab· December 2022

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Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities.
Maria J Torres, Xu Zhang, Dorothy H Slentz, Timothy R Koves, Hailee Patel

iScience· October 2022

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Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness.
Brian J Andonian, Alec Koss, Timothy R Koves, Elizabeth R Hauser, Monica J Hubal

Sci Rep· May 2022

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Disruption of STIM1-mediated Ca sensing and energy metabolism in adult skeletal muscle compromises exercise tolerance, proteostasis, and lean mass.
Rebecca J Wilson, Scott P Lyons, Timothy R Koves, Victoria G Bryson, Hengtao Zhang

Mol Metab· March 2022

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Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome.
Ashley S Williams, Timothy R Koves, Yasminye D Pettway, James A Draper, Dorothy H Slentz

iScience· January 2022

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Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Kari T Chambers, Michael A Cooper, Alison R Swearingen, Rita T Brookheart, George G Schweitzer, Timothy R Koves

JCI Insight· May 2021

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Rejuvenation of Neutrophil Functions in Association With Reduced Diabetes Risk Following Ten Weeks of Low-Volume High Intensity Interval Walking in Older Adults With Prediabetes - A Pilot Study.
David B Bartlett, Cris A Slentz, Leslie H Willis, Andrew Hoselton, Janet L Huebner, Timothy R Koves

Front Immunol· March 2021

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Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
Kyle S McCommis, Attila Kovacs, Carla J Weinheimer, Trevor M Shew, Timothy R Koves

Nat Metab· November 2020

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Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.
Phillip J White, Amanda L Lapworth, Robert W McGarrah, Lydia Coulter Kwee, Scott B Crown, Timothy R Koves

Cell Rep· November 2020

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Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles.
Brian J Andonian, Ching-Heng Chou, Olga R Ilkayeva, Timothy R Koves, Margery A Connelly

Front Immunol· October 2020

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Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure.
Michael T Davidson, Paul A Grimsrud, Ling Lai, James A Draper, Kelsey H Fisher-Wellman, Timothy R Koves

Circ Res· September 2020

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Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction.
Ashley S Williams, Timothy R Koves, Michael T Davidson, Scott B Crown, Kelsey H Fisher-Wellman

Cell Metab· January 2020

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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity.
Kevin H Lin, Abigail Xie, Justine C Rutter, Yeong-Ran Ahn, Julia M Lloyd-Cowden, Timothy R Koves

Cell Metab· May 2019

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Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle.
Alastair Khodabukus, Lauran Madden, Neel K Prabhu, Timothy R Koves, Christopher P Jackman

Biomaterials· April 2019

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Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.
Kelsey H Fisher-Wellman, James A Draper, Michael T Davidson, Ashley S Williams, Tara M Narowski, Timothy R Koves

Cell Rep· February 2019

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A Mitochondrial Progesterone Receptor Increases Cardiac Beta-Oxidation and Remodeling.
Qunsheng Dai, Creighton E Likes, Anthony L Luz, Lan Mao, Jason S Yeh, Timothy R Koves

J Endocr Soc· February 2019

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Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes.
Kelsey H Fisher-Wellman, Michael T Davidson, Tara M Narowski, Chien-Te Lin, Timothy R Koves

Cell Rep· September 2018

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Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity.
Brittany N J Davis, Jeffrey W Santoso, Michaela J Walker, Cindy S Cheng, Timothy R Koves

Tissue Eng Part C Methods· April 2017

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Metabolic Alterations Contribute to Enhanced Inflammatory Cytokine Production in Irgm1-deficient Macrophages.
Elyse A Schmidt, Brian E Fee, Stanley C Henry, Amanda G Nichols, Mari L Shinohara, Timothy R Koves

J Biol Chem· March 2017

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