Publications by authors named "Timothy L Lochmann"

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Comparison of Branched DNA to RT-qPCR Technology for the Quantitation of mRNA from mRNA-LNP Drug Product in Human Serum.
Carl A Luongo, Ashley D Wright, Timothy L Lochmann, Sweilem B Al Rihani, Jean-Claude Marshall

AAPS J· September 2025

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Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma.
Daniel A R Heisey, Sheeba Jacob, Timothy L Lochmann, Richard Kurupi, Maninderjit S Ghotra

Mol Cancer Ther· October 2021

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Venetoclax-based Rational Combinations are Effective in Models of -amplified Neuroblastoma.
Krista M Dalton, Kateryna Krytska, Timothy L Lochmann, Renata Sano, Colleen Casey

Mol Cancer Ther· August 2021

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Catastrophic ATP loss underlies a metabolic combination therapy tailored for -amplified neuroblastoma.
Krista M Dalton, Timothy L Lochmann, Konstantinos V Floros, Marissa L Calbert, Richard Kurupi

Proc Natl Acad Sci U S A· March 2021

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RNA-Binding Domains of Heterologous Viral Proteins Substituted for Basic Residues in the RSV Gag NC Domain Restore Specific Packaging of Genomic RNA.
Breanna L Rice, Timothy L Lochmann, Leslie J Parent

Viruses· March 2020

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The Ewing Family of Tumors Relies on BCL-2 and BCL-X to Escape PARP Inhibitor Toxicity.
Daniel A R Heisey, Timothy L Lochmann, Konstantinos V Floros, Colin M Coon, Krista M Powell

Clin Cancer Res· March 2019

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Increased Synthesis of MCL-1 Protein Underlies Initial Survival of -Mutant Lung Cancer to EGFR Inhibitors and Provides a Novel Drug Target.
Kyung-A Song, Yasuyuki Hosono, Crystal Turner, Sheeba Jacob, Timothy L Lochmann

Clin Cancer Res· November 2018

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BCL-2 inhibition is a promising therapeutic strategy for small cell lung cancer.
Timothy L Lochmann, Ynes M Bouck, Anthony C Faber

Oncoscience· July 2018

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Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma.
Timothy L Lochmann, Krista M Powell, Jungoh Ham, Konstantinos V Floros, Daniel A R Heisey

Sci Transl Med· May 2018

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Coamplification of protects -amplified breast cancers from targeted therapy.
Konstantinos V Floros, Timothy L Lochmann, Bin Hu, Carles Monterrubio, Mark T Hughes

Proc Natl Acad Sci U S A· March 2018

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Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM.
Kyung-A Song, Matthew J Niederst, Timothy L Lochmann, Aaron N Hata, Hidenori Kitai

Clin Cancer Res· January 2018

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Venetoclax Is Effective in Small-Cell Lung Cancers with High BCL-2 Expression.
Timothy L Lochmann, Konstantinos V Floros, Mitra Naseri, Krista M Powell, Wade Cook

Clin Cancer Res· January 2018

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Epigenetic Modifications of the PGC-1α Promoter during Exercise Induced Expression in Mice.
Timothy L Lochmann, Ravindar R Thomas, James P Bennett, Shirley M Taylor

PLoS One· March 2016

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Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination.
Jungoh Ham, Carlotta Costa, Renata Sano, Timothy L Lochmann, Erin M Sennott

Cancer Cell· February 2016

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Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus.
Breanna L Rice, Rebecca J Kaddis, Matthew S Stake, Timothy L Lochmann, Leslie J Parent

Front Microbiol· October 2015

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Alterations in the MA and NC domains modulate phosphoinositide-dependent plasma membrane localization of the Rous sarcoma virus Gag protein.
Shorena Nadaraia-Hoke, Darrin V Bann, Timothy L Lochmann, Nicole Gudleski-O'Regan, Leslie J Parent

J Virol· March 2013

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NC-mediated nucleolar localization of retroviral gag proteins.
Timothy L Lochmann, Darrin V Bann, Eileen P Ryan, Andrea R Beyer, Annie Mao

Virus Res· February 2013

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Intermolecular interactions between retroviral Gag proteins in the nucleus.
Scott P Kenney, Timothy L Lochmann, Cullen L Schmid, Leslie J Parent

J Virol· January 2008

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