Publications by authors named "Timothy M Thomson"

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Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells.
Míriam Tarrado-Castellarnau, Carles Foguet, Josep Tarragó-Celada, Marc Palobart, Claudia Hernández-Carro, Timothy M Thomson

Oncogene· September 2025

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Induction of the Inflammasome by the SARS-CoV-2 Accessory Protein ORF9b, Abrogated by Small-Molecule ORF9b Homodimerization Inhibitors.
Erika Zodda, Mònica Pons, Natàlia DeMoya-Valenzuela, Cristina Calvo-González, Cristina Benítez-Rodríguez, Timothy M Thomson

J Med Virol· February 2025

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Metabolic and mitochondria alterations induced by SARS-CoV-2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10.
Blanca D López-Ayllón, Silvia Marin, Marco Fariñas Fernández, Tránsito García-García, Raúl Fernández-Rodríguez, Timothy M Thomson

J Med Virol· July 2024

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Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 M Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation.
Maria Nuria Peralta-Moreno, Yago Mena, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Timothy M Thomson

Int J Mol Sci· June 2024

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Autonomous metabolic reprogramming and oxidative stress characterize endothelial dysfunction in acute myocardial infarction.
Erika Zodda, Olga Tura-Ceide, Nicholas L Mills, Josep Tarragó-Celada, Marina Carini, Timothy M Thomson

Elife· November 2023

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On the importance for drug discovery of a transnational Latin American database of natural compound structures.
Timothy M Thomson

Front Pharmacol· June 2023

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Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 M Main Protease Inhibitors.
Maria Nuria Peralta-Moreno, Vanessa Anton-Muñoz, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Timothy M Thomson

Pharmaceuticals (Basel)· April 2023

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A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes.
Leire Pedrosa, Carles Foguet, Helena Oliveres, Iván Archilla, Marta García de Herreros, Timothy M Thomson

Front Immunol· September 2022

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Recovery of serum testosterone levels is an accurate predictor of survival from COVID-19 in male patients.
Emily Toscano-Guerra, Mónica Martínez-Gallo, Iria Arrese-Muñoz, Anna Giné, Noelia Díaz-Troyano, Timothy M Thomson

BMC Med· March 2022

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Discovery of Diverse Natural Products as Inhibitors of SARS-CoV-2 M Protease through Virtual Screening.
Jaime Rubio-Martínez, Ana Jiménez-Alesanco, Laura Ceballos-Laita, David Ortega-Alarcón, Sonia Vega, Timothy M Thomson

J Chem Inf Model· December 2021

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Potential Protective Effect from COVID-19 Conferred by Altitude: A Longitudinal Analysis in Peru During Full Lockdown.
Timothy M Thomson, Fresia Casas, Harold Andre Guerrero, Rómulo Figueroa-Mujíca, Francisco C Villafuerte

High Alt Med Biol· June 2021

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C1 esterase inhibitor and the contact system in COVID-19.
Timothy M Thomson, Emily Toscano-Guerra, Ernesto Casis, Rosanna Paciucci

Br J Haematol· August 2020

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The Tumor Microenvironment in Colorectal Cancer Therapy.
Leire Pedrosa, Francis Esposito, Timothy M Thomson, Joan Maurel

Cancers (Basel)· August 2019

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Metabolic Plasticity and Epithelial-Mesenchymal Transition.
Timothy M Thomson, Cristina Balcells, Marta Cascante

J Clin Med· July 2019

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Metabolic Alterations in Cardiopulmonary Vascular Dysfunction.
Valérie Françoise Smolders, Erika Zodda, Paul H A Quax, Marina Carini, Joan Albert Barberà, Timothy M Thomson

Front Mol Biosci· January 2019

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Untargeted metabolomics reveals distinct metabolic reprogramming in endothelial cells co-cultured with CSC and non-CSC prostate cancer cell subpopulations.
Anusha Jayaraman, Praveen Kumar, Silvia Marin, Pedro de Atauri, Francesca Mateo, Timothy M Thomson

PLoS One· March 2018

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Model-driven discovery of long-chain fatty acid metabolic reprogramming in heterogeneous prostate cancer cells.
Igor Marín de Mas, Esther Aguilar, Erika Zodda, Cristina Balcells, Silvia Marin, Timothy M Thomson

PLoS Comput Biol· January 2018

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Epithelial plasticity in cancer: beyond metastasis.
Timothy M Thomson, Pedro L Fernández

Aging (Albany NY)· January 2018

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MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition.
Míriam Tarrado-Castellarnau, Pedro de Atauri, Josep Tarragó-Celada, Jordi Perarnau, Mariia Yuneva, Timothy M Thomson

Mol Syst Biol· October 2017

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MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells.
Lourdes Sánchez-Cid, Mònica Pons, Juan José Lozano, Nuria Rubio, Marta Guerra-Rebollo, Timothy M Thomson

Oncotarget· October 2017

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A key role for transketolase-like 1 in tumor metabolic reprogramming.
Santiago Diaz-Moralli, Esther Aguilar, Silvia Marin, Johannes F Coy, Mieke Dewerchin, Timothy M Thomson

Oncotarget· August 2016

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Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program.
Esther Aguilar, Igor Marin de Mas, Erika Zodda, Silvia Marin, Fionnuala Morrish, Timothy M Thomson

Stem Cells· May 2016

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SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations.
Francesca Mateo, Oscar Meca-Cortés, Toni Celià-Terrassa, Yolanda Fernández, Ibane Abasolo, Timothy M Thomson

Mol Cancer· October 2014

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Infrequent loss of luminal differentiation in ductal breast cancer metastasis.
Julia Calvo, Lourdes Sánchez-Cid, Montserrat Muñoz, Juan José Lozano, Timothy M Thomson

PLoS One· September 2014

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Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.
Lide Alaña, Marta Sesé, Verónica Cánovas, Yolanda Punyal, Yolanda Fernández, Timothy M Thomson

Mol Cancer· March 2014

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