Publications by authors named "Timothy Maughan"

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The colorectal liver metastasis growth pattern phenotype is not dependent on genotype.
Diederik J Höppener, Sanne M L Verheul, Pieter M H Nierop, Florian E Buisman, Boris Galjart, Timothy S Maughan

Br J Cancer· October 2025

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Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer.
Joseph C Ward, Melissa Morgan, James Wood, Connor Woolley, Albert Antao Nobre de Menezes, Timothy Maughan

J Pathol· September 2025

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Contact X-ray brachytherapy in rectal cancer: A systematic review and meta-analysis.
Simon G Powell, James N R Wyatt, Christopher Rao, Amandeep Dhadda, Muneeb Ul Haq, Timothy S Maughan

Eur J Surg Oncol· July 2025

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The potential benefit of encorafenib plus cetuximab with chemotherapy compared with standard of care in people with BRAF V600E-mutant metastatic colorectal cancer in the BREAKWATER study: a plain language summary.
Scott Kopetz, Takayuki Yoshino, Eric Van Cutsem, Cathy Eng, Tae Won Kim, Timothy S Maughan

Future Oncol· June 2025

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Encorafenib, Cetuximab, and mFOLFOX6 in -Mutated Colorectal Cancer.
Elena Elez, Takayuki Yoshino, Lin Shen, Sara Lonardi, Eric Van Cutsem, Timothy S Maughan

N Engl J Med· June 2025

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Encorafenib, cetuximab and chemotherapy in BRAF-mutant colorectal cancer: a randomized phase 3 trial.
Scott Kopetz, Takayuki Yoshino, Eric Van Cutsem, Cathy Eng, Tae Won Kim, Timothy S Maughan

Nat Med· March 2025

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Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location.
Christopher Wills, Katie Watts, Amy Houseman, Timothy S Maughan, David Fisher

Sci Rep· January 2025

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Prognostic value of liver metastases in colorectal cancer treated by systemic therapy: An ARCAD pooled analysis.
Romain Cohen, Morteza Raeisi, Benoist Chibaudel, Qian Shi, Takayuki Yoshino, Timothy S Maughan

Eur J Cancer· August 2024

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Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors.
Enric Domingo, Sanjay Rathee, Andrew Blake, Leslie Samuel, Graeme Murray, Timothy S Maughan

EBioMedicine· August 2024

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Author Correction: Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Timothy S Maughan

Nat Genet· June 2024

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Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer.
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Timothy S Maughan

Nat Genet· March 2024

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Integrated Clinical-Molecular Classification of Colorectal Liver Metastases: A Biomarker Analysis of the Phase 3 New EPOC Randomized Clinical Trial.
Rohan R Katipally, Carlos A Martinez, Siân A Pugh, John A Bridgewater, John N Primrose, Timothy S Maughan

JAMA Oncol· September 2023

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Relationship between 233 colorectal cancer risk loci and survival in 1926 patients with advanced disease.
Christopher Wills, Amy Houseman, Katie Watts, Timothy S Maughan, David Fisher

BJC Rep· June 2023

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Germline variation in RASAL2 may predict survival in patients with RAS-activated colorectal cancer.
Christopher Wills, Katie Watts, Timothy S Maughan, David Fisher, Nada A Al-Tassan

Genes Chromosomes Cancer· June 2023

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Development of multidrug-resistant in the biofilm of a peritoneal-venous shunt.
Romany M Redman, Timothy D Maughan, Charles B Smith, Peter F Crossno, Donald L Granger

IDCases· May 2023

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Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Timothy Maughan

Nat Genet· March 2023

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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Ceres Fernandez-Rozadilla, Maria Timofeeva, Zhishan Chen, Philip Law, Minta Thomas, Timothy Maughan

Nat Genet· January 2023

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Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Timothy S Maughan

Nat Commun· January 2023

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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Dustin J Flanagan, Raheleh Amirkhah, David F Vincent, Nuray Gunduz, Pauline Gentaz, Timothy S Maughan

Nat Commun· December 2022

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Ester Gil Vazquez, Nadia Nasreddin, Gabriel N Valbuena, Eoghan J Mulholland, Hayley L Belnoue-Davis, Timothy Maughan

Cell Stem Cell· November 2022

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A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy.
Liam F Spurr, Carlos A Martinez, Rohan R Katipally, Soumya C Iyer, Sian A Pugh, Timothy S Maughan

NPJ Precis Oncol· October 2022

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Spend less to achieve more: Economic analysis of intermittent versus continuous cetuximab in KRAS wild-type patients with metastatic colorectal cancer.
Raymond H Henderson, Declan French, Ethna McFerran, Richard Adams, Harpreet Wasan, Timothy S Maughan

J Cancer Policy· September 2022

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Practical guidance for running late-phase platform protocols for clinical trials: lessons from experienced UK clinical trials units.
Sharon B Love, Fay Cafferty, Claire Snowdon, Karen Carty, Joshua Savage, Timothy Maughan

Trials· September 2022

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Ester Gil Vasquez, Nadia Nasreddin, Gabriel N Valbuena, Eoghan J Mulholland, Hayley L Belnoue-Davis, Timothy Maughan

Cell Stem Cell· August 2022

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