Publications by authors named "Timothy McKeithan"

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Key regulatory roles of PRDM1 in human NK-cell differentiation and activation.
Xuxiang Liu, Yunfei Shi, Jibin Zhang, Kunal Shetty, Krystie Chew, Timothy W McKeithan

Leukemia· December 2025

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Cooperative role of distinctive TP53 and PTEN combined loss in the peripheral T cell lymphoma-GATA3 molecular subgroup.
Waseem G Lone, Jiayu Yu, Xuxiang Liu, Dylan T Jochum, Alyssa Bouska, Timothy W McKeithan

Sci Adv· October 2025

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High-grade B-cell lymphoma not otherwise specified, with diffuse large B-cell lymphoma gene expression signatures: Genomic analysis and potential therapeutics.
Waseem Lone, Alyssa Bouska, Tyler A Herek, Catalina Amador, Joo Song, Timothy W McKeithan

Am J Hematol· January 2025

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MiR-17∼92 is involved in NF-κB activation via targeting the ubiquitin-editing proteins to mediate RIP1 complex polyubiquitinations in ABC-DLBCL.
Xiaoyan Zhang, Xuan Zhang, Xin Huang, Javeed Iqbal, Timothy W McKeithan

Clin Immunol· August 2024

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Genomic profiling identifies distinct genetic subtypes in extra-nodal natural killer/T-cell lymphoma.
Gehong Dong, Xuxiang Liu, Lifu Wang, Wenjuan Yin, Alyssa Bouska, Timothy W McKeithan

Leukemia· August 2022

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Genome-Wide miRNA Expression Profiling of Molecular Subgroups of Peripheral T-cell Lymphoma.
Waseem Lone, Alyssa Bouska, Sunandini Sharma, Catalina Amador, Mallick Saumyaranjan, Timothy W McKeithan

Clin Cancer Res· November 2021

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Genetic manipulation of primary human natural killer cells to investigate the functional and oncogenic roles of PRDM1.
Gehong Dong, Yuping Li, Logan Lee, Xuxiang Liu, Yunfei Shi, Timothy W McKeithan

Haematologica· September 2021

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Molecular and Genomic Landscape of Peripheral T-Cell Lymphoma.
Javeed Iqbal, Catalina Amador, Timothy W McKeithan, Wing C Chan

Cancer Treat Res· July 2019

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L-Type Cav 1.2 Calcium Channel-α-1C Regulates Response to Rituximab in Diffuse Large B-Cell Lymphoma.
Jiu-Yang Zhang, Pei-Pei Zhang, Wen-Ping Zhou, Jia-Yu Yu, Zhi-Hua Yao, Timothy W McKeithan

Clin Cancer Res· July 2019

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The miR-17~92 cluster activates mTORC1 in mantle cell lymphoma by targeting multiple regulators in the STK11/AMPK/TSC/mTOR pathway.
Chunsun Jiang, Chengfeng Bi, Xiaoxing Jiang, Tian Tian, Xin Huang, Timothy W McKeithan

Br J Haematol· May 2019

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Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma.
Tayla B Heavican, Alyssa Bouska, Jiayu Yu, Waseem Lone, Catalina Amador, Timothy W McKeithan

Blood· April 2019

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Multi-Kinase Inhibitor with Anti-p38γ Activity in Cutaneous T-Cell Lymphoma.
Xu Hannah Zhang, Sangkil Nam, Jun Wu, Chih-Hong Chen, Xuxiang Liu, Timothy McKeithan

J Invest Dermatol· November 2018

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Flow cytometric sorting coupled with exon capture sequencing identifies somatic mutations in archival lymphoma tissues.
Nenggang Jiang, Christopher Chen, Qiang Gong, Kristen Shields, Yuping Li, Timothy W McKeithan

Lab Invest· November 2017

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Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets.
Alyssa Bouska, Chengfeng Bi, Waseem Lone, Weiwei Zhang, Ambreen Kedwaii, Timothy W McKeithan

Blood· October 2017

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Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data.
Qiang Gong, Chao Wang, Weiwei Zhang, Javeed Iqbal, Yang Hu, Timothy W McKeithan

Sci Rep· September 2017

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Inhibition of 4EBP phosphorylation mediates the cytotoxic effect of mechanistic target of rapamycin kinase inhibitors in aggressive B-cell lymphomas.
Chengfeng Bi, Xuan Zhang, Ting Lu, Xiaoyan Zhang, Xianhuo Wang, Timothy W McKeithan

Haematologica· April 2017

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Diagnostic and Biological Significance of KIR Expression Profile Determined by RNA-Seq in Natural Killer/T-Cell Lymphoma.
Can Küçük, Xiaozhou Hu, Qiang Gong, Bei Jiang, Adam Cornish, Timothy McKeithan

Am J Pathol· June 2016

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Comment on: Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma, by Yoo et al.
Qiang Gong, Chao Wang, Joseph Rohr, Andrew L Feldman, Wing C Chan, Timothy W McKeithan

Haematologica· June 2016

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IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma.
Chao Wang, Timothy W McKeithan, Qiang Gong, Weiwei Zhang, Alyssa Bouska

Blood· October 2015

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Global promoter methylation analysis reveals novel candidate tumor suppressor genes in natural killer cell lymphoma.
Can Küçük, Xiaozhou Hu, Bei Jiang, David Klinkebiel, Huimin Geng, Timothy W McKeithan

Clin Cancer Res· April 2015

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Lack of evidence that HACE1 is not a tumor suppressor gene in NKTCL: to the editor-in-chief.
Can Küçük, Xiaozhou Hu, Timothy McKeithan, Wing C Chan

Am J Pathol· April 2015

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Global microRNA expression profiling uncovers molecular markers for classification and prognosis in aggressive B-cell lymphoma.
Javeed Iqbal, Yulei Shen, Xin Huang, Yanyan Liu, Laura Wake, Timothy W McKeithan

Blood· February 2015

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Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells.
Can Küçük, Bei Jiang, Xiaozhou Hu, Wenyan Zhang, John K C Chan, Timothy McKeithan

Nat Commun· January 2015

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EZH2 mutations in follicular lymphoma from different ethnic groups and associated gene expression alterations.
Shuangping Guo, John K C Chan, Javeed Iqbal, Timothy McKeithan, Kai Fu

Clin Cancer Res· June 2014

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Activation of the STAT3 signaling pathway is associated with poor survival in diffuse large B-cell lymphoma treated with R-CHOP.
Xin Huang, Bin Meng, Javeed Iqbal, B Belinda Ding, Anamarija M Perry, Timothy W McKeithan

J Clin Oncol· December 2013

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