Publications by authors named "Timothy Moeller"

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A drug repurposing approach reveals targetable epigenetic pathways in hypnozoites.
Steven P Maher, Malina A Bakowski, Amélie Vantaux, Erika L Flannery, Chiara Andolina, Timothy Moeller

Elife· September 2025

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SLC13A5 is a novel transcriptional target of the pregnane X receptor and sensitizes drug-induced steatosis in human liver.
Linhao Li, Haishan Li, Brandy Garzel, Hui Yang, Tatsuya Sueyoshi, Timothy Moeller

Mol Pharmacol· April 2015

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Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes.
Caitlin Lynch, Yongmei Pan, Linhao Li, Scott Heyward, Timothy Moeller

Toxicol Appl Pharmacol· August 2014

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Aldehyde oxidase activity in donor-matched fresh and cryopreserved human hepatocytes and assessment of variability in 75 donors.
J Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward, Timothy Moeller

Drug Metab Dispos· June 2014

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Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling.
Hui Yang, Brandy Garzel, Scott Heyward, Timothy Moeller, Paul Shapiro

Mol Pharmacol· February 2014

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Assessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format.
Timothy A Moeller, Sunita J Shukla, Menghang Xia

Assay Drug Dev Technol· February 2012

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Automated triplexed hepatocyte-based viability and CYP1A and -3A induction assays.
Brad Larson, Timothy Moeller, Peter Banks, James J Cali

J Biomol Screen· September 2011

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A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background.
Montserrat García-Closas, David W Hein, Debra Silverman, Núria Malats, Meredith Yeager, Timothy Moeller

Pharmacogenet Genomics· April 2011

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Identification of clinically used drugs that activate pregnane X receptors.
Sunita J Shukla, Srilatha Sakamuru, Ruili Huang, Timothy A Moeller, Paul Shinn

Drug Metab Dispos· January 2011

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Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes.
Mark A Doll, Yu Zang, Timothy Moeller, David W Hein

J Pharmacol Exp Ther· August 2010

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