Publications by authors named "Timothy N Phoenix"

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Preclinical Evaluation of the Efficacy of a Cyclin-dependent Kinase Inhibitor Ribociclib in Combination with Letrozole Against Patient-Derived Glioblastoma Cells.
Sidharth N Gadgil, Aniruddha S Karve, Gary A Gudelsky, Bhavesh B Gabani, Mario Medvedovic, Timothy N Phoenix

Mol Cancer Ther· September 2025

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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas.
Sara Labiano, Javier Marco-Sanz, Iker Ausejo-Mauleon, Virginia Laspidea, Reyes Hernández-Osuna, Timothy N Phoenix

Cell Rep Med· July 2025

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Taking the "lazy" way identifies KCNB2 as a regulator of SHH-MB maintenance.
Jaldeep Langhnoja, Timothy N Phoenix

Dev Cell· June 2025

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Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG.
Ian Mersich, Sunny Congrove, Matthew Horchar, Roman Caceres, Ranjithmenon Muraleedharan, Timothy N Phoenix

bioRxiv· May 2025

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FOXR2 Targets LHX6+/DLX+ Neural Lineages to Drive Central Nervous System Neuroblastoma.
Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Michael McNicholas, Steven Hébert, Timothy N Phoenix

Cancer Res· January 2025

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The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
Daniel de la Nava, Iker Ausejo-Mauleon, Virginia Laspidea, Marisol Gonzalez-Huarriz, Andrea Lacalle, Timothy N Phoenix

Neuro Oncol· August 2024

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NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14.
Jennifer Patritti-Cram, Eric P Rahrmann, Tilat A Rizvi, Katherine C Scheffer, Timothy N Phoenix

iScience· July 2024

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MYC Promotes Aggressive Growth and Metastasis of a WNT-Medulloblastoma Mouse Model.
Rachel Hartley, Timothy N Phoenix

Dev Neurosci· June 2024

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New Insights into the Developmental Neurobiology of Brain Tumors.
Timothy N Phoenix

Dev Neurosci· June 2024

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A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance.
Aniruddha S Karve, Janki M Desai, Sidharth N Gadgil, Nimita Dave, Trisha M Wise-Draper, Timothy N Phoenix

Int J Mol Sci· March 2024

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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Ryan J Duchatel, Evangeline R Jackson, Sarah G Parackal, Dylan Kiltschewskij, Izac J Findlay, Timothy N Phoenix

J Clin Invest· February 2024

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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Timothy N Phoenix

Mol Cell· January 2024

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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory.
Iker Ausejo-Mauleon, Sara Labiano, Daniel de la Nava, Virginia Laspidea, Marta Zalacain, Timothy N Phoenix

Cancer Cell· November 2023

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Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.
Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Timothy N Phoenix

bioRxiv· May 2023

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Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
Aniruddha S Karve, Janki M Desai, Nimita Dave, Trisha M Wise-Draper, Gary A Gudelsky, Timothy N Phoenix

Cancer Chemother Pharmacol· October 2022

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FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits.
Jessica W Tsai, Paloma Cejas, Dayle K Wang, Smruti Patel, David W Wu, Timothy N Phoenix

Cancer Res· September 2022

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The origins of medulloblastoma tumours in humans.
Timothy N Phoenix

Nature· September 2022

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Generation of immunocompetent syngeneic allograft mouse models for pediatric diffuse midline glioma.
Aimée du Chatinier, Michaël H Meel, Arvid I Das, Dennis S Metselaar, Piotr Waranecki, Timothy N Phoenix

Neurooncol Adv· May 2022

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Glioblastoma genetic drivers dictate the function of tumor-associated macrophages/microglia and responses to CSF1R inhibition.
Rohit Rao, Rong Han, Sean Ogurek, Chengbin Xue, Lai Man Wu, Timothy N Phoenix

Neuro Oncol· April 2022

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PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
Prasidda Khadka, Zachary J Reitman, Sophie Lu, Graham Buchan, Gabrielle Gionet, Timothy N Phoenix

Nat Commun· February 2022

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Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders.
Maud Martin, Simon Vermeiren, Naguissa Bostaille, Marie Eubelen, Daniel Spitzer, Timothy N Phoenix

Science· February 2022

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Mapping Angiopoietin1 Expression in the Developing and Adult Brain.
Xin Wei, Selin Jessa, Claudia L Kleinman, Timothy N Phoenix

Dev Neurosci· January 2022

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Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas.
Stefan R Sweha, Chan Chung, Siva Kumar Natarajan, Pooja Panwalkar, Matthew Pun, Timothy N Phoenix

Sci Transl Med· October 2021

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Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas.
Xin Wei, Michaël H Meel, Marjolein Breur, Marianna Bugiani, Esther Hulleman, Timothy N Phoenix

Acta Neuropathol Commun· August 2021

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