Publications by authors named "Timothy Pardee"

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Novel devimistat results in complete remissions in heavily pretreated Burkitt lymphoma in a phase 2 trial.
Raphael Steiner, Liana Nikolaenko, Ranjit Nair, Venkatraman Seshan, Swetha Kambhampati Thiruvengadam, Timothy S Pardee

Blood Adv· November 2025

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Pilot study of an inpatient physical activity intervention for older adults treated intensively for acute myeloid leukemia.
Heidi D Klepin, Janet A Tooze, Walter J Rejeski, Shannon Mihalko, Timothy S Pardee

Blood Adv· October 2025

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Non-Blast Phase Chronic Myelogenous Leukemia Presenting as Bilateral Infiltration of the Optic Nerve.
Effie Z Rahman, Matthew Ellis, Timothy Pardee, Rajiv Shah

Ophthalmic Surg Lasers Imaging Retina· February 2025

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Devimistat (CPI-613) With Modified Fluorouarcil, Oxaliplatin, Irinotecan, and Leucovorin (FFX) Versus FFX for Patients With Metastatic Adenocarcinoma of the Pancreas: The Phase III AVENGER 500 Study.
Philip A Philip, Vaibhav Sahai, Nathan Bahary, Amit Mahipal, Anup Kasi, Timothy Pardee

J Clin Oncol· November 2024

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Safety and tolerability of AMG 330 in adults with relapsed/refractory AML: a phase 1a dose-escalation study.
Farhad Ravandi, Marion Subklewe, Roland B Walter, Pankit Vachhani, Gert Ossenkoppele, Timothy S Pardee

Leuk Lymphoma· September 2024

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Devimistat plus chemotherapy vs chemotherapy alone for older relapsed or refractory patients with AML: results of the ARMADA trial.
Timothy S Pardee, Bayard L Powell, Richard A Larson, Joseph Maly, Michael Keng

Blood Neoplasia· June 2024

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Comparison of survival for metastatic pancreatic cancer patients treated with CPI-613 versus resected borderline-resectable pancreatic cancer patients.
Christopher W Mangieri, Cristian D Valenzuela, Ian B Solsky, Richard A Erali, Timothy Pardee

J Surg Oncol· October 2023

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Assessment of an embedded primary care-derived electronic health record (EHR) frailty index (eFI) in older adults with acute myeloid leukemia.
Justin J Cheng, Janet A Tooze, Kathryn E Callahan, Nicholas M Pajewski, Timothy S Pardee

J Geriatr Oncol· September 2023

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Real-world outcomes of adult patients with acute lymphoblastic leukemia treated with a modified CALGB 10102 regimen.
Daniel R Reed, Margaux Wooster, Scott Isom, Leslie R Ellis, Dianna S Howard, Timothy S Pardee

Ann Hematol· April 2023

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Pyruvate Dehydrogenase Inhibition Leads to Decreased Glycolysis, Increased Reliance on Gluconeogenesis and Alternative Sources of Acetyl-CoA in Acute Myeloid Leukemia.
Rebecca Anderson, Kristin M Pladna, Nathaniel J Schramm, Frances B Wheeler, Steven Kridel, Timothy S Pardee

Cancers (Basel)· January 2023

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P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia.
Kevin H Lin, Justine C Rutter, Abigail Xie, Shane T Killarney, Camille Vaganay, Timothy S Pardee

Nat Cancer· July 2022

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Adenosine Monophosphate Activated Protein Kinase (AMPK) enhances chemotherapy response in Acute Myeloid Leukemia (AML).
Lais Ghiraldeli, Rebecca Anderson, Kristin Pladna, Timothy S Pardee

Cancer Lett· June 2022

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Tailoring a physical activity intervention to older adults receiving intensive chemotherapy for acute myeloid leukemia (AML): One size does not fit all.
Heidi D Klepin, Janet A Tooze, Jack Rejeski, Shannon Mihalko, Timothy S Pardee

J Geriatr Oncol· May 2022

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hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy.
Yong Lu, Gang Xue, Ningbo Zheng, Kun Han, Wenzhong Yang, Timothy Pardee

Brief Bioinform· March 2022

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Phase II trial of cytarabine and mitoxantrone with devimistat in acute myeloid leukemia.
Rebecca Anderson, Lance D Miller, Scott Isom, Jeff W Chou, Kristin M Pladna, Timothy S Pardee

Nat Commun· March 2022

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Re-induction therapy in adult patients with acute myeloid leukemia with ≤20 % blasts: A retrospective cohort study.
Kavya K Kannan, Paz Vellanki, Scott Isom, Bernard Tawfik, Allison Winter, Timothy S Pardee

Leuk Res· December 2021

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Efficacy of 10-day decitabine in acute myeloid leukemia.
Ian M Bouligny, Vivek Mehta, Scott Isom, Leslie R Ellis, Rupali R Bhave, Timothy S Pardee

Leuk Res· April 2021

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A Pilot Phase II Study of the Feasibility and Efficacy of Vincristine Sulfate Liposome Injection in Patients With Relapsed or Refractory Acute Myeloid Leukemia.
Mary Beth Seegars, Ryan Woods, Leslie R Ellis, Rupali Roy Bhave, Dianna S Howard, Timothy S Pardee

J Hematol· February 2021

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Geriatric assessment and survival among older adults receiving postremission therapy for acute myeloid leukemia.
Mohammed Saad, Kah Poh Loh, Janet A Tooze, Timothy S Pardee, Leslie R Ellis

Blood· December 2020

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Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results.
Michael Heuser, Neil Palmisiano, Ioannis Mantzaris, Alice Mims, Courtney DiNardo, Timothy Pardee

Leukemia· November 2020

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The Novel Phospholipid Mimetic KPC34 Is Highly Active Against Acute Myeloid Leukemia with Activated Protein Kinase C.
Peter M Alexander, Gregory L Kucera, Kristin M Pladna, Timothy S Pardee

Transl Oncol· July 2020

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The prognostic value of standardized phase angle in adults with acute leukemia: A prospective study.
Samuel J Yates, Susan Lyerly, Megan Manuel, Janet A Tooze, Heidi D Klepin, Timothy S Pardee

Cancer Med· April 2020

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Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801.
Guido Marcucci, Susan Geyer, Kristina Laumann, Weiqiang Zhao, Donna Bucci, Timothy S Pardee

Blood Adv· February 2020

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Devimistat in combination with high dose cytarabine and mitoxantrone compared with high dose cytarabine and mitoxantrone in older patients with relapsed/refractory acute myeloid leukemia: ARMADA 2000 Phase III study.
Timothy S Pardee, Sanjeev Luther, Marc Buyse, Bayard L Powell, Jorge Cortes

Future Oncol· October 2019

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Gilteritinib or Chemotherapy for Relapsed or Refractory -Mutated AML.
Alexander E Perl, Giovanni Martinelli, Jorge E Cortes, Andreas Neubauer, Ellin Berman, Timothy Pardee

N Engl J Med· October 2019

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