Publications by authors named "Timothy R Blake"

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mRNA Delivery to the Lung Vascular Endothelium by Dicationic Charge-Altering Releasable Transporters.
Mahmoud M AbdElwakil, Jeffrey Ni, Summer Ramsay-Burrough, Paul Joshua Hurst, Rebecca L McClellan, Timothy R Blake

J Am Chem Soc· November 2025

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Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs.
Timothy R Blake, Ole A W Haabeth, Adrienne Sallets, Rebecca L McClellan, Trevor J Del Castillo

Bioconjug Chem· March 2023

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Fingolimod-Conjugated Charge-Altering Releasable Transporters Efficiently and Specifically Deliver mRNA to Lymphocytes In Vivo and In Vitro.
Stefano Testa, Ole A W Haabeth, Timothy R Blake, Trevor J Del Castillo, Debra K Czerwinski

Biomacromolecules· July 2022

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An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory.
Ole A W Haabeth, Julian J K Lohmeyer, Adrienne Sallets, Timothy R Blake, Idit Sagiv-Barfi

ACS Cent Sci· July 2021

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An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory.
Ole A W Haabeth, Julian J K Lohmeyer, Adrienne Sallets, Timothy R Blake, Idit Sagiv-Barfi

bioRxiv· May 2021

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Synthesis and mechanistic investigations of pH-responsive cationic poly(aminoester)s.
Timothy R Blake, Wilson C Ho, Christopher R Turlington, Xiaoyu Zang, Melanie A Huttner

Chem Sci· February 2020

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Reversible RNA acylation for control of CRISPR-Cas9 gene editing.
Maryam Habibian, Colin McKinlay, Timothy R Blake, Anna M Kietrys, Robert M Waymouth

Chem Sci· December 2019

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Local Delivery of , , and mRNA Kindles Global Anticancer Immunity.
Ole Audun Werner Haabeth, Timothy R Blake, Colin J McKinlay, Anders A Tveita, Adrienne Sallets

Cancer Res· April 2019

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mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice.
Ole A W Haabeth, Timothy R Blake, Colin J McKinlay, Robert M Waymouth, Paul A Wender

Proc Natl Acad Sci U S A· September 2018

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Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals.
Colin J McKinlay, Jessica R Vargas, Timothy R Blake, Jonathan W Hardy, Masamitsu Kanada

Proc Natl Acad Sci U S A· January 2017

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Organocatalytic ring-opening polymerization of morpholinones: new strategies to functionalized polyesters.
Timothy R Blake, Robert M Waymouth

J Am Chem Soc· July 2014

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Chemoselective Pd-catalyzed oxidation of polyols: synthetic scope and mechanistic studies.
Kevin Chung, Steven M Banik, Antonio G De Crisci, David M Pearson, Timothy R Blake

J Am Chem Soc· May 2013

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