Publications by authors named "Timothy R Crother"

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Sirtuin 1 Activation Mitigates Murine Vasculitis Severity by Promoting Autophagy and Mitophagy.
Asli E Atici, Prasant K Jena, Thacyana T Carvalho, Benjamin L Ross, Emily A Aubuchon, Timothy R Crother

bioRxiv· September 2025

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pDCs drive immunopathology by sensing oxidized mitochondrial DNA.
Moshe Arditi, Timothy R Crother

Nat Immunol· July 2025

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Interleukin-1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease.
Shuang Chen, Asli Savas, Asli Atici, Youngho Lee, Malcolm Lane, Timothy R Crother

J Am Heart Assoc· June 2025

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Hypothermia protects against ventilator-induced lung injury by limiting IL-1β release and NETs formation.
Nobuyuki Nosaka, Vanessa Borges, Daisy Martinon, Timothy R Crother, Moshe Arditi

Elife· June 2025

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Identification of and NLRP3 inflammasome activation in Alzheimer's disease retina.
Bhakta Prasad Gaire, Yosef Koronyo, Jean-Philippe Vit, Alexandre Hutton, Natalie Swerdlow, Timothy R Crother

bioRxiv· June 2025

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Identification of and NLRP3 inflammasome activation in Alzheimer's disease retina.
Bhakta Prasad Gaire, Yosef Koronyo, Jean-Philippe Vit, Alexandre Hutton, Natalie Swerdlow, Timothy R Crother

Res Sq· June 2025

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Intestinal Microbiota Contributes to the Development of Cardiovascular Inflammation and Vasculitis in Mice.
Prasant K Jena, Daiko Wakita, Angela C Gomez, Thacyana T Carvalho, Asli E Atici, Timothy R Crother

Circ Res· April 2025

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Hypothermia protects against ventilator-induced lung injury by limiting IL-1β release and NETs formation.
Nobuyuki Nosaka, Vanessa Borges, Daisy Martinon, Timothy R Crother, Moshe Arditi

bioRxiv· April 2025

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Redundant role of PAD2 and PAD4 in the development of cardiovascular lesions in a mouse model of Kawasaki disease vasculitis.
Talita P Domiciano, Youngho Lee, Thacyana T Carvalho, Daiko Wakita, Daisy Martinon, Timothy R Crother

Clin Exp Immunol· November 2024

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Long-term cardiovascular inflammation and fibrosis in a murine model of vasculitis induced by cell wall extract.
Ana Paula Lombardi Pereira, Emily Aubuchon, Debbie P Moreira, Malcolm Lane, Thacyana T Carvalho, Timothy R Crother

Front Immunol· July 2024

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The intestinal microbiota contributes to the development of immune-mediated cardiovascular inflammation and vasculitis in mice.
Prasant K Jena, Daiko Wakita, Angela C Gomez, Thacyana T Carvalho, Asli E Atici, Timothy R Crother

bioRxiv· June 2024

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in Alzheimer's disease pathology.
Lalita Subedi, Bhakta Prasad Gaire, Yosef Koronyo, Maya Koronyo-Hamaoui, Timothy R Crother

Front Neurosci· May 2024

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Mitochondrial quality control in health and cardiovascular diseases.
Asli E Atici, Timothy R Crother, Magali Noval Rivas

Front Cell Dev Biol· November 2023

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NLRP3 Inflammasome Mediates Immune-Stromal Interactions in Vasculitis.
Rebecca A Porritt, David Zemmour, Masanori Abe, Youngho Lee, Meena Narayanan, Timothy R Crother

Circ Res· October 2021

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Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.
Stefanie Marek-Iannucci, Asli B Ozdemir, Debbie Moreira, Angela C Gomez, Malcolm Lane, Timothy R Crother

JCI Insight· September 2021

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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Hongxu Xian, Yuan Liu, Alexandra Rundberg Nilsson, Raphaella Gatchalian, Timothy R Crother

Immunity· July 2021

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Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model.
Gantsetseg Tumurkhuu, Shuang Chen, Erica N Montano, Duygu Ercan Laguna, Gabriela De Los Santos, Timothy R Crother

Front Immunol· April 2021

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Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury.
Nobuyuki Nosaka, Daisy Martinon, Debbie Moreira, Timothy R Crother, Moshe Arditi

Front Immunol· March 2021

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Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.
Jargalsaikhan Dagvadorj, Karolina Mikulska-Ruminska, Gantsetseg Tumurkhuu, Rojo A Ratsimandresy, Jessica Carriere, Timothy R Crother

Proc Natl Acad Sci U S A· January 2021

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Autophagy Limits Inflammasome During Infection.
Timothy R Crother, Rebecca A Porritt, Jargalsaikhan Dagvadorj, Gantsetseg Tumurkhuu, Anatoly V Slepenkin

Front Immunol· August 2020

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Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice.
Shuang Chen, Janet L Markman, Kenichi Shimada, Timothy R Crother, Malcolm Lane

JACC Basic Transl Sci· June 2020

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MD-2 as a possible therapeutic target for atherosclerosis.
Shuang Chen, Timothy R Crother

EBioMedicine· May 2020

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Loss of testosterone impairs anti-tumor neutrophil function.
Janet L Markman, Rebecca A Porritt, Daiko Wakita, Malcolm E Lane, Daisy Martinon, Timothy R Crother

Nat Commun· March 2020

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Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation.
Magali Noval Rivas, Daiko Wakita, Michael K Franklin, Thacyana T Carvalho, Amanda Abolhesn, Timothy R Crother

Immunity· September 2019

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Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis.
Harry H Matundan, Jon Sin, Magali Noval Rivas, Michael C Fishbein, Thomas J Lehman, Timothy R Crother

JCI Insight· February 2019

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