Publications by authors named "Timothy Rumbell"

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Inferring Parameters of Pyramidal Neuron Excitability in Mouse Models of Alzheimer's Disease Using Biophysical Modeling and Deep Learning.
Soheil Saghafi, Timothy Rumbell, Viatcheslav Gurev, James Kozloski, Francesco Tamagnini

Bull Math Biol· March 2024

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Novel and flexible parameter estimation methods for data-consistent inversion in mechanistic modelling.
Timothy Rumbell, Jaimit Parikh, James Kozloski, Viatcheslav Gurev

R Soc Open Sci· November 2023

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The intracellular domain of major histocompatibility class-I proteins is essential for maintaining excitatory spine density and synaptic ultrastructure in the brain.
Maciej J Lazarczyk, Brett A Eyford, Merina Varghese, Hitesh Arora, Lonna Munro, Timothy Rumbell

Sci Rep· April 2023

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Sex-Specific Neural Networks of Cued Threat Conditioning: A Pilot Study.
Kamryn C du Plessis, Sreetama Basu, Timothy H Rumbell, Elizabeth K Lucas

Front Syst Neurosci· May 2022

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Generative adversarial networks for construction of virtual populations of mechanistic models: simulations to study Omecamtiv Mecarbil action.
Jaimit Parikh, Timothy Rumbell, Xenia Butova, Tatiana Myachina, Jorge Corral Acero

J Pharmacokinet Pharmacodyn· February 2022

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Neuronal population models reveal specific linear conductance controllers sufficient to rescue preclinical disease phenotypes.
Sushmita L Allam, Timothy H Rumbell, Tuan Hoang-Trong, Jaimit Parikh, James R Kozloski

iScience· November 2021

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Dimensions of control for subthreshold oscillations and spontaneous firing in dopamine neurons.
Timothy Rumbell, James Kozloski

PLoS Comput Biol· September 2019

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Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation.
J Christopher Octeau, Mohitkumar R Gangwani, Sushmita L Allam, Duy Tran, Shuhan Huang, Timothy H Rumbell

Cell Rep· May 2019

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Automated evolutionary optimization of ion channel conductances and kinetics in models of young and aged rhesus monkey pyramidal neurons.
Timothy H Rumbell, Danel Draguljić, Aniruddha Yadav, Patrick R Hof, Jennifer I Luebke

J Comput Neurosci· August 2016

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25th Annual Computational Neuroscience Meeting: CNS-2016.
Tatyana O. Sharpee, Alain Destexhe, Mitsuo Kawato, Vladislav Sekulić, Frances K. Skinner, Timothy Rumbell

BMC Neurosci· August 2016

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Functional consequences of age-related morphologic changes to pyramidal neurons of the rhesus monkey prefrontal cortex.
Patrick J Coskren, Jennifer I Luebke, Doron Kabaso, Susan L Wearne, Aniruddha Yadav, Timothy Rumbell

J Comput Neurosci· April 2015

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A spiking self-organizing map combining STDP, oscillations, and continuous learning.
Timothy Rumbell, Susan L Denham, Thomas Wennekers

IEEE Trans Neural Netw Learn Syst· May 2014

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