Publications by authors named "Timothy Shuen"

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Atypical memory B cells acquire Breg phenotypes in hepatocellular carcinoma.
Shi Yong Neo, Timothy Wai Ho Shuen, Shruti Khare, Joni Chong, Maichan Lau

JCI Insight· February 2025

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Single-cell RNA sequencing reveals anti-tumor potency of CD56 NK cells and CD8 T cells in humanized mice via PD-1 and TIGIT co-targeting.
Wai Nam Liu, Sarah L Harden, Shawn Lu Wen Tan, Rachel Jun Rou Tan, Shin Yie Fong, Timothy Wai Ho Shuen

Mol Ther· November 2024

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GATA4 downregulation enhances CCL20-mediated immunosuppression in hepatocellular carcinoma.
N Jannah M Nasir, Samuel Chuah, Timothy Shuen, Aldo Prawira, Rebecca Ba

Hepatol Commun· September 2024

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The association between tumour heterogeneity and immune evasion mechanisms in hepatocellular carcinoma and its clinical implications.
Kaina Chen, Timothy W H Shuen, Pierce K H Chow

Br J Cancer· August 2024

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Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma.
Neslihan Arife Kaya, David Tai, Xinru Lim, Jia Qi Lim, Mai Chan Lau, Timothy Wai Ho Shuen

J Immunother Cancer· August 2023

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A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes.
Anna Wuestefeld, Viktoriia Iakovleva, Shirlyn Xue Ling Yap, Agnes Bee Leng Ong, Daniel Q Huang, Timothy Wai Ho Shuen

Cancer Res· February 2023

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Hypoxia-driven immunosuppression by Treg and type-2 conventional dendritic cells in HCC.
Sheena Suthen, Chun Jye Lim, Phuong H D Nguyen, Charles-Antoine Dutertre, Hannah L H Lai, Timothy W H Shuen

Hepatology· November 2022

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Extracellular Vesicles May Predict Response to Radioembolization and Sorafenib Treatment in Advanced Hepatocellular Carcinoma: An Exploratory Analysis from the SORAMIC Trial.
Timothy Wai Ho Shuen, Marianna Alunni-Fabbroni, Elif Öcal, Peter Malfertheiner, Moritz Wildgruber

Clin Cancer Res· September 2022

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TCR repertoire characteristics predict clinical response to adoptive CTL therapy against nasopharyngeal carcinoma.
Guoping Wang, Poorva Mudgal, Liuyang Wang, Timothy Wai Ho Shuen, Haiyang Wu

Oncoimmunology· October 2021

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Analysis and Validation of Human Targets and Treatments Using a Hepatocellular Carcinoma-Immune Humanized Mouse Model.
Yue Zhao, Jiaxu Wang, Wai Nam Liu, Shin Yie Fong, Timothy Wai Ho Shuen

Hepatology· September 2021

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Monocytic Myeloid-Derived Suppressor Cells Underpin Resistance to Adoptive T Cell Therapy in Nasopharyngeal Carcinoma.
Richard Hopkins, Wenwei Xiang, Damien Marlier, Veonice Bijin Au, Qianting Ching, Timothy Shuen

Mol Ther· February 2021

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Targeted Inhibition of Purine Metabolism Is Effective in Suppressing Hepatocellular Carcinoma Progression.
Yong Chun Chong, Tan Boon Toh, Zhiling Chan, Quy Xiao Xuan Lin, Dexter Kai Hao Thng, Timothy Shuen

Hepatol Commun· September 2020

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Assessment of PARP4 as a candidate breast cancer susceptibility gene.
Aldo Prawira, Prabhakaran Munusamy, Jimin Yuan, Claire Hian Tzer Chan, Geok Ling Koh, Timothy Wai Ho Shuen

Breast Cancer Res Treat· August 2019

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Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy.
Yue Zhao, Timothy Wai Ho Shuen, Tan Boon Toh, Xue Ying Chan, Min Liu

Gut· October 2018

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