Publications by authors named "Timothy W Failes"

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Invasion-Block and S-MARVEL: A high-content screening and image analysis platform identifies ATM kinase as a modulator of melanoma invasion and metastasis.
Dajiang Guo, Russell Jurek, Kimberley A Beaumont, Danae S Sharp, Sioh-Yang Tan, Timothy W Failes

Proc Natl Acad Sci U S A· November 2023

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High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.
Chelsea Mayoh, Jie Mao, Jinhan Xie, Gabor Tax, Shu-Oi Chow, Timothy W Failes

Cancer Res· August 2023

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Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy.
Annatina S Schnegg-Kaufmann, Julie A I Thoms, Golam Sarower Bhuyan, Henry R Hampton, Lachlin Vaughan, Timothy W Failes

Blood· March 2023

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Anti-cancer potential of synergistic phytochemical combinations is influenced by the genetic profile of prostate cancer cell lines.
Carol A Gano, Shadma Fatima, Timothy W Failes, Gregory M Arndt, Mila Sajinovic

Front Nutr· March 2023

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βIII-tubulin suppression enhances the activity of Amuvatinib to inhibit cell proliferation in c-Met positive non-small cell lung cancer cells.
Simon Brayford, Alastair Duly, Wee Siang Teo, Tanya Dwarte, Estrella Gonzales-Aloy, Timothy W Failes

Cancer Med· February 2023

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Systematic Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia.
Mawar Karsa, Emma Ronca, Angelika Bongers, Anna Mariana, Ernest Moles, Timothy W Failes

Front Oncol· January 2022

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The important role of routine cytopathology in pediatric precision oncology.
Jinhan Xie, Amit Kumar, M Emmy M Dolman, Chelsea Mayoh, Dong-Anh Khuong-Quang, Timothy W Failes

Cancer Cytopathol· October 2021

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Doxorubicin-Loaded Gold Nanoarchitectures as a Therapeutic Strategy against Diffuse Intrinsic Pontine Glioma.
Caitlin Ung, Maria Tsoli, Jie Liu, Domenico Cassano, Salvador Pocoví-Martínez, Timothy W Failes

Cancers (Basel)· March 2021

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Accelerating development of high-risk neuroblastoma patient-derived xenograft models for preclinical testing and personalised therapy.
Alvin Kamili, Andrew J Gifford, Nancy Li, Chelsea Mayoh, Shu-Oi Chow, Timothy W Failes

Br J Cancer· March 2020

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Synthesis and anticancer evaluation of 3-substituted quinolin-4-ones and 2,3-dihydroquinolin-4-ones.
Santosh Rajput, Christopher R Gardner, Timothy W Failes, Greg M Arndt, David Stc Black

Bioorg Med Chem· January 2014

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Structural and anticancer properties of hydrogen bonded diphenyl phosphate adducts of Pt(IV) complexes: the importance of pKa matching.
Timothy W Failes, Andrew R Battle, Catherine Chen, Carleen Cullinane, Ross Woods

J Inorg Biochem· October 2012

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Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells.
Timothy W Failes, Gorjana Mitic, Heba Abdel-Halim, Sela T Po'uha, Marjorie Liu

PLoS One· August 2012

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Cellular uptake and distribution of cobalt complexes of fluorescent ligands.
Natsuho Yamamoto, Sarah Danos, Paul D Bonnitcha, Timothy W Failes, Elizabeth J New

J Biol Inorg Chem· August 2008

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Bioreductive activation and drug chaperoning in cobalt pharmaceuticals.
Matthew D Hall, Timothy W Failes, Natsuho Yamamoto, Trevor W Hambley

Dalton Trans· September 2007

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Studies of a cobalt(III) complex of the MMP inhibitor marimastat: a potential hypoxia-activated prodrug.
Timothy W Failes, Carleen Cullinane, Connie I Diakos, Natsuho Yamamoto, J Guy Lyons

Chemistry· June 2007

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Towards bioreductively activated prodrugs: Fe(III) complexes of hydroxamic acids and the MMP inhibitor marimastat.
Timothy W Failes, Trevor W Hambley

J Inorg Biochem· March 2007

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Models of hypoxia activated prodrugs: Co(III) complexes of hydroxamic acids.
Timothy W Failes, Trevor W Hambley

Dalton Trans· April 2006

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Structural investigations of palladium(II) and platinum(II) complexes of salicylhydroxamic acid.
Matthew D Hall, Timothy W Failes, David E Hibbs, Trevor W Hambley

Inorg Chem· March 2002

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