Publications by authors named "Timothy W Schacker"

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Pre-treatment Microbiome Diversity and Function is associated with Expansion of Cytotoxic and Regulatory Immune Populations after N-803 treatment in People with HIV.
Ashma Chakrawarti, Ross T Cromarty, Christopher M Basting, Jodi Anderson, Ty A Schroeder, Timothy W Schacker

bioRxiv· October 2025

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Wastewater Measures of SARS-CoV-2 Accurately Predict Frequency of Symptomatic Infections in the Community.
Charles R Doss, Mark J Osborn, Stacey Stark, Joshua Rhein, Jacalynn Donkersgoed, Timothy W Schacker

J Infect Dis· September 2025

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Impact of the IL-15 superagonist N-803 on lymphatic reservoirs of HIV.
Joshua Rhein, Jeffrey G Chipman, Gregory J Beilman, Ross Cromarty, Kevin Escandón, Timothy W Schacker

JCI Insight· July 2025

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Naturally transmitted mouse viruses highlight the heterogeneity of virus transmission dynamics in the dirty mouse model.
Dira S Putri, Frances K Shepherd, Autumn E Sanders, Shanley N Roach, Sridevi Jay, Timothy W Schacker

J Virol· June 2025

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SARS-CoV-2 infection is associated with intestinal permeability, systemic inflammation, and microbial dysbiosis in hospitalized patients.
Christopher M Basting, Robert Langat, Courtney A Broedlow, Candace R Guerrero, Tyler D Bold, Timothy W Schacker

Microbiol Spectr· November 2024

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Safety and Virologic Impact of Haploidentical NK Cells Plus Interleukin 2 or N-803 in HIV Infection.
Jeffrey S Miller, Joshua Rhein, Zachary B Davis, Sarah Cooley, David McKenna, Timothy W Schacker

J Infect Dis· May 2024

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Initial productive and latent HIV infections originate in vivo by infection of resting T cells.
Stephen W Wietgrefe, Jodi Anderson, Lijie Duan, Peter J Southern, Paul Zuck, Timothy W Schacker

J Clin Invest· November 2023

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The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2 and Necroptosis, Pyroptosis, and PANoptosis.
Luca Schifanella, Jodi Anderson, Garritt Wieking, Peter J Southern, Spinello Antinori, Timothy W Schacker

J Infect Dis· May 2023

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Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.
Noemia S Lima, Maryam Musayev, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Timothy W Schacker

Nat Commun· December 2022

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Detecting Sources of Immune Activation and Viral Rebound in HIV Infection.
Stephen W Wietgrefe, Lijie Duan, Jodi Anderson, Guillermo Marqués, Mark Sanders, Timothy W Schacker

J Virol· August 2022

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The Defenders of the Alveolus Succumb in COVID-19 Pneumonia to SARS-CoV-2, Necroptosis, Pyroptosis and Panoptosis.
Luca Schifanella, Jodi Anderson, Garritt Wieking, Peter J Southern, Spinello Antinori, Timothy W Schacker

bioRxiv· August 2022

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Paradoxically Greater Persistence of HIV RNA-Positive Cells in Lymphoid Tissue When ART Is Initiated in the Earliest Stage of Infection.
Eugène Kroon, Suthat Chottanapund, Supranee Buranapraditkun, Carlo Sacdalan, Donn J Colby, Timothy W Schacker

J Infect Dis· June 2022

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Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.
Noemia S Lima, Maryam Musayev, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Timothy W Schacker

bioRxiv· June 2022

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Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA-vaccinated patients with inflammatory bowel disease.
Kathryn A Pape, Thamotharampillai Dileepan, William E Matchett, Charles Ellwood, Samuel Stresemann, Timothy W Schacker

JCI Insight· June 2022

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Efficacy of Losartan in Hospitalized Patients With COVID-19-Induced Lung Injury: A Randomized Clinical Trial.
Michael A Puskarich, Nicholas E Ingraham, Lisa H Merck, Brian E Driver, David A Wacker, Timothy W Schacker

JAMA Netw Open· March 2022

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Safety and virologic impact of the IL-15 superagonist N-803 in people living with HIV: a phase 1 trial.
Jeffrey S Miller, Zachary B Davis, Erika Helgeson, Cavan Reilly, Ann Thorkelson, Timothy W Schacker

Nat Med· February 2022

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Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response.
Guoxin Wu, Paul Zuck, Shih Lin Goh, Jeffrey M Milush, Poonam Vohra, Timothy W Schacker

J Infect Dis· November 2021

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A novel wastewater-based epidemiology indexing method predicts SARS-CoV-2 disease prevalence across treatment facilities in metropolitan and regional populations.
Richard G Melvin, Emily N Hendrickson, Nabiha Chaudhry, Onimitein Georgewill, Rebecca Freese, Timothy W Schacker

Sci Rep· November 2021

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High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines.
Kathryn A Pape, Thamotharampillai Dileepan, Amanda J Kabage, Daria Kozysa, Rodolfo Batres, Timothy W Schacker

Cell Rep· October 2021

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A multi-center phase II randomized clinical trial of losartan on symptomatic outpatients with COVID-19.
Michael A Puskarich, Nathan W Cummins, Nicholas E Ingraham, David A Wacker, Ronald A Reilkoff, Timothy W Schacker

EClinicalMedicine· July 2021

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Translocated microbiome composition determines immunological outcome in treated HIV infection.
Krystelle Nganou-Makamdop, Aarthi Talla, Ashish Arunkumar Sharma, Sam Darko, Amy Ransier, Timothy W Schacker

Cell· July 2021

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Initial determination of COVID-19 seroprevalence among outpatients and healthcare workers in Minnesota using a novel SARS-CoV-2 total antibody ELISA.
Stefani N Thomas, Ghaith Altawallbeh, Christopher P Zaun, Kathryn A Pape, Jennifer M Peters, Timothy W Schacker

Clin Biochem· April 2021

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The Lymphoid Tissue Pharmacokinetics of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide in HIV-Infected Persons.
Courtney V Fletcher, Anthony T Podany, Ann Thorkelson, Lee C Winchester, Timothy Mykris, Timothy W Schacker

Clin Pharmacol Ther· November 2020

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Abundant HIV-infected cells in blood and tissues are rapidly cleared upon ART initiation during acute HIV infection.
Louise Leyre, Eugène Kroon, Claire Vandergeeten, Carlo Sacdalan, Donn J Colby, Timothy W Schacker

Sci Transl Med· March 2020

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Factor Xa Inhibition Reduces Coagulation Activity but Not Inflammation Among People With HIV: A Randomized Clinical Trial.
Jason V Baker, Julian Wolfson, Tess Peterson, Micah Mooberry, Matthew Gissel, Timothy W Schacker

Open Forum Infect Dis· February 2020

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