Publications by authors named "Timothy Ware"

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Proteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors.
Hayden A Sharma, Michael Bielecki, Meredith A Holm, Ty M Thompson, Yue Yin, Timothy B Ware

J Am Chem Soc· May 2025

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validation of the palmitoylation cycle as a therapeutic target in -mutant cancer.
Matthew Decker, Benjamin J Huang, Timothy Ware, Christopher Boone, Michelle Tang

bioRxiv· March 2025

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Lipidomic profiling of mouse brain and human neuron cultures reveals a role for in mTOR-dependent neuronal migration.
Isaac Tang, Ashna Nisal, Alex Reed, Timothy B Ware, Anide Johansen

Sci Transl Med· January 2025

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Proteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors.
Hayden A Sharma, Michael Bielecki, Meredith A Holm, Ty M Thompson, Yue Yin, Timothy B Ware

bioRxiv· January 2025

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Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling.
Miaomiao Chen, Myungsun Shin, Timothy B Ware, Giulia Donvito, Karan H Muchhala

Proc Natl Acad Sci U S A· December 2023

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TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids.
Alex Reed, Timothy Ware, Haoxin Li, J Fernando Bazan, Benjamin F Cravatt

Nat Chem Biol· March 2023

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ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer.
Harun Ozturk, Harun Cingoz, Turan Tufan, Jiekun Yang, Sara J Adair, Timothy B Ware

Dev Cell· June 2022

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Advances in chemical proteomic evaluation of lipid kinases-DAG kinases as a case study.
Timothy B Ware, Ku-Lung Hsu

Curr Opin Chem Biol· December 2021

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RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal.
Syed S Hussain, Tuyet-Minh Tran, Timothy B Ware, Melissa A Luse, Christopher T Prevost

Cell Rep· July 2021

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Monoacylglycerol Lipase Inhibition Using JZL184 Attenuates Paw Inflammation and Functional Deficits in a Mouse Model of Inflammatory Arthritis.
Sara R Nass, Floyd F Steele, Timothy B Ware, Adam H Libby, Ku-Lung Hsu

Cannabis Cannabinoid Res· June 2021

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Metabolomics analysis of lipid metabolizing enzyme activity.
Timothy B Ware, Myungsun Shin, Ku-Lung Hsu

Methods Enzymol· June 2020

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DAGL-Beta Functions as a PUFA-Specific Triacylglycerol Lipase in Macrophages.
Myungsun Shin, Timothy B Ware, Ku-Lung Hsu

Cell Chem Biol· March 2020

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Global targeting of functional tyrosines using sulfur-triazole exchange chemistry.
Heung Sik Hahm, Emmanuel K Toroitich, Adam L Borne, Jeffrey W Brulet, Adam H Libby, Timothy B Ware

Nat Chem Biol· February 2020

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Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering.
Timothy B Ware, Caroline E Franks, Mitchell E Granade, Mingxing Zhang, Kee-Beom Kim

Nat Chem Biol· February 2020

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Lipid-metabolizing serine hydrolases in the mammalian central nervous system: endocannabinoids and beyond.
Myungsun Shin, Timothy B Ware, Hyeon-Cheol Lee, Ku-Lung Hsu

Biochim Biophys Acta Mol Cell Biol Lipids· June 2019

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