Publications by authors named "Timothy Watkins"

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Cilofexor in non-cirrhotic primary sclerosing cholangitis (PRIMIS): a randomised, double-blind, multicentre, placebo-controlled, phase 3 trial.
Michael Trauner, Cynthia Levy, Atsushi Tanaka, Zachary Goodman, Douglas Thorburn, Timothy R Watkins

Lancet Gastroenterol Hepatol· January 2026

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Reply to McMahon et al.
Timothy A Watkins, Jacqueline K Brockhurst, Gregory Germain, Ellen F Foxman

J Infect Dis· December 2025

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Development and validation of a predictive 6-min walk score in patients with idiopathic pulmonary fibrosis.
Steven D Nathan, Jie Gao, Ho Cheol Kim, Abhimanyu Chandel, Henry Chen, Timothy R Watkins

Eur Respir J· November 2025

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The ANTICIPATE-NASH Models Stratify Better the Risk of Clinical Events Than Histology in Metabolic Dysfunction-Associated Steatotic Liver Disease Patients With Advanced Chronic Liver Disease.
Laia Aceituno, Juan Bañares, Mònica Pons, Jesús Rivera-Esteban, Clara Sabiote, Timothy R Watkins

Gastroenterology· November 2025

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Multivariate analysis of glycogenes reveals coordinated regulation of immunoglobulin glycosylation in an immortalized human B cell system.
Christine D Wiggins, Marina Sangés Ametllé, Claire Wu, Timothy A Watkins, Kristin L Boswell

bioRxiv· October 2025

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Antidiabetic and lipid-lowering medication use inversely linked with serum biomarkers of liver fibrosis.
Jun Wang, Dora Ding, Xiaorong Shao, Lily Ma, Jun Xu, Timothy R Watkins

Diabetes Obes Metab· August 2025

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Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic-Associated Fatty Liver Disease.
Islam R Younis, Elijah J Weber, Cara Nelson, Ann R Qin, Timothy R Watkins

J Clin Pharmacol· July 2025

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Nasal biomarker testing to rule out viral respiratory infection and triage samples: a test performance study.
Julien A R Amat, Sarah N Dudgeon, Nagarjuna R Cheemarla, Timothy A Watkins, Alex B Green

EBioMedicine· July 2025

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Detection of Live Attenuated Measles Virus in the Respiratory Tract Following Subcutaneous Measles-Mumps-Rubella Vaccination.
Timothy A Watkins, Jacqueline K Brockhurst, Gregory Germain, Diane E Griffin, Ellen F Foxman

J Infect Dis· April 2025

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Pharmacokinetics and Safety of Cilofexor and Firsocostat in Healthy Japanese and Non-Japanese Participants.
Islam R Younis, Cara Nelson, Elijah J Weber, Gong Shen, Ann R Qin, Timothy R Watkins

J Clin Pharmacol· December 2024

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AI-based automation of enrollment criteria and endpoint assessment in clinical trials in liver diseases.
Janani S Iyer, Dinkar Juyal, Quang Le, Zahil Shanis, Harsha Pokkalla, Timothy R Watkins

Nat Med· October 2024

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Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Firsocostat, a Liver-Targeted Inhibitor of Acetyl-CoA Carboxylase.
Elijah J Weber, Islam R Younis, Cara Nelson, Ann R Qin, Timothy R Watkins

Clin Pharmacokinet· October 2024

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High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children.
Timothy A Watkins, Alex B Green, Julien A R Amat, Nagarjuna R Cheemarla, Katrin Hänsel

J Exp Med· September 2024

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Filgotinib in Active Noninfectious Uveitis: The HUMBOLDT Randomized Clinical Trial.
Sunil K Srivastava, Timothy R Watkins, Quan Dong Nguyen, Sumit Sharma, David K Scales

JAMA Ophthalmol· September 2024

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Cilofexor in Patients With Compensated Cirrhosis Due to Primary Sclerosing Cholangitis: An Open-Label Phase 1B Study.
Cynthia Levy, Stephen Caldwell, Parvez Mantry, Velimir Luketic, Charles S Landis, Timothy R Watkins

Clin Transl Gastroenterol· August 2024

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Pharmacokinetics and Safety of Firsocostat, an Acetyl-Coenzyme A Carboxylase Inhibitor, in Participants with Mild, Moderate, and Severe Hepatic Impairment.
Islam R Younis, Cara Nelson, Elijah J Weber, Ann R Qin, Timothy R Watkins

J Clin Pharmacol· July 2024

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Considerations for viral co-infection studies in human populations.
Taylor Chin, Ellen F Foxman, Timothy A Watkins, Marc Lipsitch

mBio· July 2024

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Viral Interference During Influenza A-SARS-CoV-2 Coinfection of the Human Airway Epithelium and Reversal by Oseltamivir.
Nagarjuna R Cheemarla, Timothy A Watkins, Valia T Mihaylova, Ellen F Foxman

J Infect Dis· May 2024

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Derivation and validation of a noninvasive prediction tool to identify pulmonary hypertension in patients with IPF: Evolution of the model FORD.
Steven D Nathan, Abhimanyu Chandel, Ya Wang, Jiawei Xu, Lixin Shao, Timothy R Watkins

J Heart Lung Transplant· April 2024

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ALPINE2: Efficacy and safety of 14-day vs 28-day inhaled aztreonam for Pa eradication in children with cystic fibrosis.
Francis J Gilchrist, Stephanie Bui, Silvia Gartner, Susanna A McColley, Harm Tiddens, Timothy R Watkins

J Cyst Fibros· January 2024

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Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena: An Official American Thoracic Society Report.
Milica Vukmirovic, Kambez H Benam, Jason J Rose, Scott Turner, Chelsea M Magin, Timothy Watkins

Ann Am Thorac Soc· January 2024

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Effect of Hepatic Impairment on the Pharmacokinetics and Pharmacodynamics of Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor Agonist.
Islam R Younis, Chia-Hsiang Hsueh, Cara Nelson, Andrew N Billin, Mun Sang Yue, Timothy R Watkins

J Clin Pharmacol· September 2023

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Effects of filgotinib on semen parameters and sex hormones in male patients with inflammatory diseases: results from the phase 2, randomised, double-blind, placebo-controlled MANTA and MANTA-RAy studies.
Walter Reinisch, Wayne Hellstrom, Radboud J E M Dolhain, Suresh Sikka, René Westhovens, Timothy R Watkins

Ann Rheum Dis· August 2023

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Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials.
Toby M Maher, Paul Ford, Kevin K Brown, Ulrich Costabel, Vincent Cottin, Timothy R Watkins

JAMA· May 2023

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AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials.
Janani S Iyer, Harsha Pokkalla, Charles Biddle-Snead, Oscar Carrasco-Zevallos, Mary Lin, Timothy R Watkins

medRxiv· April 2023

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