Publications by authors named "Timour Baslan"

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SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence.
Kaloyan M Tsanov, Francisco M Barriga, Yu-Jui Ho, Direna Alonso-Curbelo, Geulah Livshits, Timour Baslan

Nat Cancer· November 2025

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α-Ketoglutarate dehydrogenase is a therapeutic vulnerability in acute myeloid leukemia.
Scott E Millman, Almudena Chaves-Perez, Sudha Janaki-Raman, Yu-Jui Ho, John P Morris, Timour Baslan

Blood· March 2025

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Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer.
Julien Dilly, Megan T Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Timour Baslan

Cancer Discov· November 2024

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Integrating the Study of Polyploidy Across Organisms, Tissues, and Disease.
John P Morris, Timour Baslan, Douglas E Soltis, Pamela S Soltis, Donald T Fox

Annu Rev Genet· November 2024

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Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Timour Baslan

Nature· November 2024

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DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility.
Shuangyi Xu, Ning Wang, Michael V Zuccaro, Jeannine Gerhardt, Rajan Iyyappan, Timour Baslan

Nat Commun· June 2024

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Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.
Urszula N Wasko, Jingjing Jiang, Tanner C Dalton, Alvaro Curiel-Garcia, A Cole Edwards, Timour Baslan

Nature· May 2024

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Metastatic site influences driver gene function in pancreatic cancer.
Kaloyan M Tsanov, Francisco M Barriga, Yu-Jui Ho, Direna Alonso-Curbelo, Geulah Livshits, Timour Baslan

bioRxiv· March 2024

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Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease.
Josef Leibold, Kaloyan M Tsanov, Corina Amor, Yu-Jui Ho, Francisco J Sánchez-Rivera, Timour Baslan

Nat Cancer· February 2024

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Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.
Il-Kyu Kim, Mark S Diamond, Salina Yuan, Samantha B Kemp, Benjamin M Kahn, Timour Baslan

Nat Commun· February 2024

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DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility.
Shuangyi Xu, Ning Wang, Michael V Zuccaro, Jeannine Gerhardt, Timour Baslan

bioRxiv· December 2023

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Correction: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999.
Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan

Blood Cancer J· July 2023

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Measurable residual disease by flow cytometry in acute myeloid leukemia is prognostic, independent of genomic profiling.
Chezi Ganzel, Zhuoxin Sun, Timour Baslan, Yanming Zhang, Mithat Gönen

Leuk Res· December 2022

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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.
Francisco M Barriga, Kaloyan M Tsanov, Yu-Jui Ho, Noor Sohail, Amy Zhang, Timour Baslan

Nat Cancer· November 2022

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Mcm2 hypomorph leads to acute leukemia or hematopoietic stem cell failure, dependent on genetic context.
Toshihiro Matsukawa, Mianmian Yin, Timour Baslan, Yang Jo Chung, Dengchao Cao

FASEB J· September 2022

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Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999.
Franck Rapaport, Kenneth Seier, Yaseswini Neelamraju, Duane Hassane, Timour Baslan

Blood Cancer J· September 2022

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Replication stress impairs chromosome segregation and preimplantation development in human embryos.
Katherine L Palmerola, Selma Amrane, Alejandro De Los Angeles, Shuangyi Xu, Ning Wang, Timour Baslan

Cell· August 2022

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Ordered and deterministic cancer genome evolution after p53 loss.
Timour Baslan, John P Morris, Zhen Zhao, Jose Reyes, Yu-Jui Ho

Nature· August 2022

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BMP2/SMAD pathway activation in JAK2/p53-mutant megakaryocyte/erythroid progenitors promotes leukemic transformation.
Bing Li, Wenbin An, Hua Wang, Timour Baslan, Shoron Mowla

Blood· June 2022

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Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin.
András N Spaan, Anna-Lena Neehus, Emmanuel Laplantine, Frederik Staels, Masato Ogishi, Timour Baslan

Science· June 2022

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Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells.
Stefan Klingler, Kuo-Shun Hsu, Guoqiang Hua, Maria Laura Martin, Mohammad Adileh, Timour Baslan

JCI Insight· March 2022

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Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma.
Ravikanth Maddipati, Robert J Norgard, Timour Baslan, Komal S Rathi, Amy Zhang

Cancer Discov· February 2022

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Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer.
Stella V Paffenholz, Camilla Salvagno, Yu-Jui Ho, Matthew Limjoco, Timour Baslan

Proc Natl Acad Sci U S A· February 2022

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Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts.
Hendrik J Kuiken, Sabin Dhakal, Laura M Selfors, Chandler M Friend, Tian Zhang, Timour Baslan

Oncogene· January 2022

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Mapping Replication Timing in Single Mammalian Cells.
Daniel A Bartlett, Vishnu Dileep, Timour Baslan, David M Gilbert

Curr Protoc· January 2022

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