Publications by authors named "Timucin Avsar"

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Early α-Synuclein Pathology Induces Neuroinflammation and Decreases Topoisomerase IIβ Expression in A53T Mice.
Berçem Yeman-Kıyak, Tahire Yurdakul, Aslınur Selim, Birsen Elibol, Timuçin Avşar

Inflammation· December 2025

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Niraparib Demonstrates Therapeutic Potential in Multiple Sclerosis through Inhibition of IL-17A Receptor Interaction and Promotion of Remyelination.
Muge Didem Orhan, Lalehan Oktay, Ayşe Irem Cınar, Aybek Kagan Yesil, Huseyin Tunc, Timucin Avsar

ACS Chem Neurosci· October 2025

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Comprehensive Meta-Analysis of Differentially Expressed Proteins in Cerebrospinal Fluid Associated with Multiple Sclerosis.
Elif Sakiz, Elnaz Amanzadeh Jajin, Liza Cubeddu, Roland Gamsjaeger, Timucin Avsar

Int J Mol Sci· June 2025

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Synthesis of Tryptamine-Thiazolidin-4-one Derivatives and the Combined and Evaluation of their Biological Activity and Cytotoxicity.
Seher Aydın, Yavuz Ergün, Salma Ghazy, Asuman Çelebi, Turker Kilic

ACS Omega· November 2024

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Claudin and transmembrane receptor protein gene expressions are reversely correlated in peritumoral brain edema.
Anwar Abuelrub, Berkay Paker, Turker Kilic, Timucin Avsar

Cancer Med· August 2024

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Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Mark W Youngblood, Zeynep Erson-Omay, Chang Li, Hinda Najem, Süleyman Coșkun

Nat Commun· October 2023

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Silencing of the MEG3 gene promoted anti-cancer activity and drug sensitivity in glioma.
Zehra Degirmenci, Sena Unver, Turker Kilic, Timucin Avsar

J Cell Mol Med· September 2023

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Comparison of anti-spike IgG, anti-spike IgA levels and neutralizing antibody activity induced by CoronaVac and BNT162b2 vaccines in patients with inflammatory rheumatic diseases receiving immunosuppressive therapy.
Fulya Cosan, Ozlem Unay Demirel, Demet Yalcin, Muhammed Mert Sonkaya, Isilsu Ezgi Uluisik, Timucin Avsar

BMC Rheumatol· July 2023

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Prospective outcome analysis of multiple sclerosis cases reveals candidate prognostic cerebrospinal fluid markers.
Elif Everest, Ugur Uygunoglu, Melih Tutuncu, Alper Bulbul, Umut Inci Onat, Timucin Avsar

PLoS One· June 2023

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Glycopolymer and Poly(β-amino ester)-Based Amphiphilic Block Copolymer as a Drug Carrier.
Elif L Sahkulubey Kahveci, Muhammet U Kahveci, Asuman Celebi, Timucin Avsar, Serap Derman

Biomacromolecules· November 2022

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Review on Methods, High-throughput Screening Techniques, and Cell Culture Based Assays for SARS-CoV-2.
Yuksel Cetin, Seyma Aydinlik, Aysen Gungor, Tugce Kan, Timucin Avsar

Curr Med Chem· October 2022

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IDH1 mutation activates mTOR signaling pathway, promotes cell proliferation and invasion in glioma cells.
Timucin Avsar, Tansu Bilge Kose, Muhammed Deniz Oksal, Gizem Turan, Turker Kilic

Mol Biol Rep· October 2022

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A novel BH3 mimetic Bcl-2 inhibitor promotes autophagic cell death and reduces in vivo Glioblastoma tumor growth.
Seyma Calis, Berna Dogan, Serdar Durdagi, Asuman Celebi, Ozlem Yapicier, Timucin Avsar

Cell Death Discov· October 2022

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Anti-SARS-CoV-2 and cytotoxic activity of two marine alkaloids from green alga Sonder in the Dardanelles.
Ebru Erol, Muge Didem Orhan, Timucin Avsar, Atilla Akdemir, Emine Sukran Okudan

RSC Adv· October 2022

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Antiangiogenic Molecules Suppressed Meningioma-Induced Neovascularization: A Corneal Angiogenesis Study.
Necati Tatarli, Davut Ceylan, M Deniz Oksal, Timucin Avsar, Turker Kilic

Turk Neurosurg· September 2022

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Instant determination of the artemisinin from various Artemisia annua L. extracts by LC-ESI-MS/MS and their in-silico modelling and in vitro antiviral activity studies against SARS-CoV-2.
Kubra Dogan, Ebru Erol, Muge Didem Orhan, Zehra Degirmenci, Tugce Kan, Timucin Avsar

Phytochem Anal· March 2022

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Screening of Clinically Approved and Investigation Drugs as Potential Inhibitors of SARS-CoV-2: A Combined in silico and in vitro Study.
Serdar Durdagi, Muge Didem Orhan, Busecan Aksoydan, Seyma Calis, Berna Dogan, Timucin Avsar

Mol Inform· February 2022

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The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies.
Serdar Durdagi, Timucin Avsar, Muge Didem Orhan, Muge Serhatli, Bertan Koray Balcioglu

Mol Ther· February 2022

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Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing.
Serdar Durdagi, Çağdaş Dağ, Berna Dogan, Merve Yigin, Timucin Avsar

Structure· December 2021

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Investigation of neuro-inflammatory parameters in a cuprizone induced mouse model of multiple sclerosis.
Timucin Avşar, Gökçe Çelikyapi Erdem, Gökhan Terzioğlu, Eda Tahir Turanli

Turk J Biol· October 2021

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Association of MTHFR, MTRR and RAD54L Gene Variations with Meningioma and Correlation with Tumor's Histopathological Characteristics on Turkish Cohort.
Timucin Avsar, Rashid Mohiyuddin, Seyma Calis, Ozlem Yapicier, Turker Kilic

Turk Neurosurg· July 2021

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Hybrid and TR-FRET-Guided Discovery of Novel BCL-2 Inhibitors.
Kader Sahin, Muge Didem Orhan, Timucin Avsar, Serdar Durdagi

ACS Pharmacol Transl Sci· June 2021

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Associations of meningioma molecular subgroup and tumor recurrence.
Mark W Youngblood, Danielle F Miyagishima, Lan Jin, Trisha Gupte, Chang Li

Neuro Oncol· May 2021

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An Integrated in silico Approach and in vitro Study for the Discovery of Small-Molecule USP7 Inhibitors as Potential Cancer Therapies.
Duaa Kanan, Tarek Kanan, Berna Dogan, Muge Didem Orhan, Timucin Avsar

ChemMedChem· February 2021

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Genome-wide identification of Chiari malformation type I associated candidate genes and chromosomal variations.
Timuçin AvŞar, Şeyma ÇaliŞ, Baran Yilmaz, Gülden Demİrcİ OtluoĞlu, Can Holyavkİn

Turk J Biol· December 2020

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