Publications by authors named "Ting-Wei Mu"

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Improving Proteostasis of Trafficking-Deficient GABA Receptor Variants by Activating IRE1.
Xu Fu, Ya-Juan Wang, KyungA Lee, Lucie Y Ahn, Xi Chen, Ting-Wei Mu

ACS Chem Neurosci· December 2025

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Proteostasis regulation of GABA receptors in neuronal function and disease.
Xi Chen, Ya-Juan Wang, Ting-Wei Mu

Biomed Pharmacother· May 2025

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Missense variants in GABA receptor beta2 subunit disrupt receptor biogenesis and cause loss of function.
Xi Chen, Ya-Juan Wang, Ting-Wei Mu

bioRxiv· March 2025

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frameshift variants impair GABA receptor proteostasis.
Marnie P Williams, Ya-Juan Wang, Jing-Qiong Kang, John H Perryman, Ting-Wei Mu

bioRxiv· January 2025

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Pharmacological chaperones restore proteostasis of epilepsy-associated GABA receptor variants.
Ya-Juan Wang, Hailey Seibert, Lucie Y Ahn, Ashleigh E Schaffer, Ting-Wei Mu

Pharmacol Res· October 2024

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Hsp47 promotes biogenesis of multi-subunit neuroreceptors in the endoplasmic reticulum.
Ya-Juan Wang, Xiao-Jing Di, Pei-Pei Zhang, Xi Chen, Marnie P Williams, Ting-Wei Mu

Elife· July 2024

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Adapting the endoplasmic reticulum proteostasis rescues epilepsy-associated NMDA receptor variants.
Pei-Pei Zhang, Taylor M Benske, Lucie Y Ahn, Ashleigh E Schaffer, James C Paton, Ting-Wei Mu

Acta Pharmacol Sin· February 2024

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Pathogenicity Prediction of GABA Receptor Missense Variants.
Ya-Juan Wang, Giang H Vu, Ting-Wei Mu

bioRxiv· November 2023

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Pharmacological chaperones restore proteostasis of epilepsy-associated GABA receptor variants.
Ya-Juan Wang, Hailey Seibert, Lucie Y Ahn, Ashleigh E Schaffer, Ting-Wei Mu

bioRxiv· April 2023

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Anti-seizure mechanisms of midazolam and valproate at the β2(L51M) variant of the GABA receptor.
Alibek Kuanyshbek, Meng Wang, Åsa Andersson, Marie Tuifua, Elizabeth E Palmer, Ting-Wei Mu

Neuropharmacology· December 2022

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Quantitative interactome proteomics identifies a proteostasis network for GABA receptors.
Ya-Juan Wang, Xiao-Jing Di, Ting-Wei Mu

J Biol Chem· October 2022

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The endoplasmic reticulum membrane complex promotes proteostasis of GABA receptors.
Angela L Whittsette, Ya-Juan Wang, Ting-Wei Mu

iScience· August 2022

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Protein quality control of -methyl-D-aspartate receptors.
Taylor M Benske, Ting-Wei Mu, Ya-Juan Wang

Front Cell Neurosci· July 2022

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Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABA receptors.
Meng Wang, Edmund Cotter, Ya-Juan Wang, Xu Fu, Angela L Whittsette, Ting-Wei Mu

Cell Biosci· April 2022

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Proteostasis Regulators Restore Function of Epilepsy-Associated GABA Receptors.
Xiao-Jing Di, Ya-Juan Wang, Edmund Cotter, Meng Wang, Angela L Whittsette, Ting-Wei Mu

Cell Chem Biol· January 2021

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Interactome Changes Quantified to Identify the ER Proteostasis Network to Fight Amyloid Diseases.
Ya-Juan Wang, Ting-Wei Mu

Cell Chem Biol· July 2019

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Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABAA receptors.
Yan-Lin Fu, Dong-Yun Han, Ya-Juan Wang, Xiao-Jing Di, Hai-Bo Yu, Ting-Wei Mu

PLoS One· April 2019

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LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors.
Yan-Lin Fu, Bin Zhang, Ting-Wei Mu

Biochem Biophys Res Commun· April 2019

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GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells.
Dawid Krokowski, Bo-Jhih Guan, Jing Wu, Yuke Zheng, Padmanabhan P Pattabiraman, Ting-Wei Mu

Cell Rep· December 2017

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Proteostasis Maintenance of Cys-Loop Receptors.
Yan-Lin Fu, Ya-Juan Wang, Ting-Wei Mu

Adv Protein Chem Struct Biol· August 2016

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Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation.
Xiao-Jing Di, Ya-Juan Wang, Dong-Yun Han, Yan-Lin Fu, Adam S Duerfeldt, Ting-Wei Mu

J Biol Chem· April 2016

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L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABA(A) Receptors.
Dong-Yun Han, Bo-Jhih Guan, Ya-Juan Wang, Maria Hatzoglou, Ting-Wei Mu

ACS Chem Biol· September 2015

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Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated γ-aminobutyric acid, type A (GABAA) receptors.
Dong-Yun Han, Xiao-Jing Di, Yan-Lin Fu, Ting-Wei Mu

J Biol Chem· January 2015

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The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.
Ya-Juan Wang, Bamidele O Tayo, Anupam Bandyopadhyay, Heming Wang, Tao Feng, Ting-Wei Mu

PLoS Genet· September 2014

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