Publications by authors named "Tingxu Yan"

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The Akkermansia muciniphila-tryptophan metabolism-aromatic hydrocarbon receptor axis mediates the protective effect of Schisandra chinensis pectin polysaccharide against colitis.
Xiaoyu Wu, Jiajia Wei, Rongzheng Deng, Jinyu Wang, Bo Wu, Tingxu Yan

Carbohydr Polym· March 2026

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Sanzi Yangqin Decoction alleviated epithelial barrier damage in acute lung injury by mediating CD40 in alveolar macrophages to inhibit necroptosis of pulmonary epithelial cells.
Anna Gan, Jinyu Wang, Dehong Zhang, Min Xie, Bo Wu, Tingxu Yan

Phytomedicine· November 2025

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In vitro identification and in vivo metabolic profiling of chemical constituents in seeds.
Jiahong Wang, Juan Cao, Hao Wang, Yudie Zhang, Li Jiang, Yanxiu Sun, Yiyang Du, Tingxu Yan

Food Chem X· August 2025

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Semen Ziziphi Spinosae alleviates cardiomyocyte apoptosis in rats with coronary heart disease via the AMPK/SIRT1/PGC-1α signaling pathway activation.
Anqi Bi, Rihong Liu, Min Xie, Bosai He, Tingxu Yan, Yiyang Du

Phytomedicine· July 2025

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Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway.
Meiqi Wan, Anna Gan, Jun Dai, Fei Lin, Ruixuan Wang, Tingxu Yan

J Pharm Pharmacol· June 2025

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Sanzi Yangqin Decoction improved acute lung injury by regulating the TLR2-mediated NF-κB/NLRP3 signaling pathway and inhibiting the activation of NLRP3 inflammasome.
Anna Gan, Haimiao Chen, Fei Lin, Ruixuan Wang, Bo Wu, Tingxu Yan

Phytomedicine· April 2025

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Isorhamnetin Alleviates Inflammation-Induced Crosstalk between Kynurenine Pathway and Gut Microbiota in Depressed Mice.
Mengjie Xu, Wei He, Ke Yan, Xinru Gao, Jun Li, Tingxu Yan

Biomol Ther (Seoul)· March 2025

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Schisandra chinensis lignans exerts endocannabinoids-like antidepressive effect: The phagocytotic relationship of activated CB2R-mediated M2 microglia and "stressed-but-viable" neuron.
Jinyu Wang, Haoyu Du, Mengru Li, Tingxu Yan, Ying Jia

J Ethnopharmacol· February 2025

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Multi-platform analysis revealed the substance basis and mechanism of Wei-Tong-Xin in ameliorating ENS dysfunction for dyspepsia treatment.
Xiaoying Zhang, Shiyu Wang, Jinyu Xie, Jinyu Wang, Yaru Gu, Tingxu Yan

J Ethnopharmacol· January 2025

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Schisandrin B restores M1/M2 balance through miR-124 in lipopolysaccharide-induced BV2 cells.
Yunfang Yang, Rihong Liu, Yixuan Sun, Bo Wu, Bosai He, Tingxu Yan

J Pharm Pharmacol· October 2024

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LC-MS/MS-based chemical profiling of water extracts of leaves and pharmacokinetics of their major constituents in rat plasma.
Jiahong Wang, Yiyang Du, Li Jiang, Jiahe Li, Bing Yu, Tingxu Yan

Food Chem X· October 2024

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Schisandra chinensis lignans regulate and cooperate with endogenous cannabinoid systems to ameliorate intestinal barrier injury associated with depression.
Jinyu Wang, Aijuan Zheng, Fei Lin, Xiaozhuo Zhang, Kaifang Shi, Tingxu Yan

Phytomedicine· October 2024

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Costunolide ameliorates MNNG-induced chronic atrophic gastritis through inhibiting oxidative stress and DNA damage via activation of Nrf2.
Ruixuan Wang, Youdong Zhao, Lei Zhou, Fei Lin, Meiqi Wan, Tingxu Yan

Phytomedicine· July 2024

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Non-targeted metabolomics strategy reveals the role of Geng-Nian-Shu in regulating ferroptosis in perimenopausal syndrome.
Xinyan Lv, Anqi Bi, Zhan Zhang, Jinyan Li, Yingbo Wei, Tingxu Yan

J Pharm Biomed Anal· April 2024

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Research on the mechanism of antidepressive effect of Suanzaoren Decoction through TLR4/MyD88/NF-κB pathway and Wnt/β-catenin pathway.
Yiyang Du, Tingxu Yan, Bo Wu, Bosai He, Ying Jia

J Ethnopharmacol· January 2024

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Screening the components in multi-biological samples and the comparative pharmacokinetic study in healthy and depression model rats of Suan-Zao-Ren decoction combined with a network pharmacology.
Yiyang Du, Jiahong Wang, Li Jiang, Jinyan Li, Jiahe Li, Tingxu Yan

J Ethnopharmacol· January 2024

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Suanzaoren decoction improves depressive-like behaviors by regulating the microbiota-gut-brain axis via inhibiting TLR4/NFκB/NLRP3 inflammation signal pathway.
Yiyang Du, Bosai He, Bo Wu, Tingxu Yan, Ying Jia

J Chem Neuroanat· December 2023

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A network pharmacology approach to investigate dehydrocostus lactone inhibits the proliferation and epithelial-mesenchymal transition of human gastric cancer cells via regulating the PI3K/Akt and extracellular signal-regulated kinases/mitogen-activated protein kinase signalling pathways.
Meiqi Wan, Jun Dai, Anna Gan, Jinyu Wang, Fei Lin, Xinyan Lv, Tingxu Yan

J Pharm Pharmacol· October 2023

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Spinosin protects Neuro-2a/APP695 cells from oxidative stress damage by inactivating p38.
Zhang Xiaoying, Wang Ruixuan, Wang Yiqing, X U Fanxing, Yan Tingxu

J Tradit Chin Med· October 2023

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Biomarkers based on multiplatform comprehensive analysis: A systematic analysis of Geng-Nian-Shu in perimenopausal syndrome.
Xinyan Lv, Qinghua Xu, Zhiqin Zhang, Jinyu Wang, Meiqi Wan, Tingxu Yan

J Sep Sci· September 2023

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Rhodiola wallichiana var.cholaensis protects against myocardial ischemia-reperfusion injury by attenuating oxidative stress-mediated apoptosis via enhancing Nrf2 signaling.
Tingxu Yan, Xu Li, Xin Wang, Yue Zhang, Bosai He

Int J Cardiol· August 2023

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Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Bo Wu, Anna Gan, Ruixuan Wang, Fei Lin, Tingxu Yan

J Chem Neuroanat· July 2023

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Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Xiaoying Zhang, Shiyu Wang, Yanjun Jin, Jinyu Wang, Ruixuan Wang, Xihan Yang, Tingxu Yan

J Ethnopharmacol· May 2023

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Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
Xiaoying Zhang, Xihan Yang, Shuanglin Zhang, Jinyu Wang, Mengshi Wang, Xinyan Lv, Tingxu Yan

J Pharm Pharmacol· April 2023

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A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway.
Fei Lin, Guanglin Zhang, Xihan Yang, Mengshi Wang, Ruixuan Wang, Tingxu Yan

J Ethnopharmacol· March 2023

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