Publications by authors named "Tiziana Bonaldi"

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The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumor immunity.
Sonia Cinque, Yvessa Verheyden, Sara Adnane, Alessandro Marino, Sarah Hanache, Tiziana Bonaldi

J Exp Med· January 2026

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Breaking Boundaries in Histone Modification MS-Based Detection: A Tailored Search Strategy for Unrestricted Identification of Novel Epigenetic Marks.
Alessandro Vai, Roberta Noberini, Andrea Graziadei, Daniel A Polasky, Fengchao Yu, Tiziana Bonaldi

Mol Cell Proteomics· November 2025

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Extraction of Histones from Clinical Specimens for Epigenetic Profiling by Mass Spectrometry.
Giulia Robusti, Paola Fulghieri, Tiziana Bonaldi

J Vis Exp· November 2025

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Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.
Marta Milan, Valeria Runfola, Manthan Patel, Lucia Falbo, Roberta Noberini, Tiziana Bonaldi

Nucleic Acids Res· September 2025

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A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes.
Roberta Noberini, Giulia Robusti, Alessandro Vai, Evelyn Oliva Savoia, Maria Giovanna Jodice, Tiziana Bonaldi

Nat Commun· September 2025

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Correction: HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy.
Valeria Spadotto, Chiara Ripamonti, Andrea Ghiroldi, Elisabetta Galbiati, Pietro Pozzi, Tiziana Bonaldi

Front Immunol· August 2025

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H2A.X N-terminal acetylation is a newly identified NAA40-mediated modification that is responsive to UV irradiation.
Ariel Klavaris, Costas Koufaris, Roberta Noberini, Maria Kouma, Christina Demetriadou, Tiziana Bonaldi

Epigenetics Chromatin· July 2025

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Quantifying the impact of treatment delays on breast cancer survival outcomes: a comprehensive meta-analysis.
Zoltan Ungvari, Mónika Fekete, Annamaria Buda, Andrea Lehoczki, Gyöngyi Munkácsy, Tiziana Bonaldi

Geroscience· June 2025

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Metabolic traits shape responses to LSD1-directed therapy in glioblastoma tumor-initiating cells.
Giulia Marotta, Daniela Osti, Elena Zaccheroni, Brunella Costanza, Stefania Faletti, Tiziana Bonaldi

Sci Adv· May 2025

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HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy.
Valeria Spadotto, Chiara Ripamonti, Andrea Ghiroldi, Elisabetta Galbiati, Pietro Pozzi, Tiziana Bonaldi

Front Immunol· May 2025

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Systematic genetic perturbation reveals principles underpinning robustness of the epigenetic regulatory network.
Thomas Stuart Wilson, Roberta Noberini, Eirini Moysidou, Ifeyinwa Ojukwu, Marta Milan, Tiziana Bonaldi

Nucleic Acids Res· April 2025

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Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes.
Francisco Santos, Magda Correia, Rafaela Dias, Bárbara Bola, Roberta Noberini, Tiziana Bonaldi

Aging Cell· February 2025

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Improved Mass Spectrometry-Based Methods Reveal Abundant Propionylation and Tissue-Specific Histone Propionylation Profiles.
Alessandro Vai, Roberta Noberini, Chiara Ghirardi, Dieggo Rodrigues de Paula, Michele Carminati, Tiziana Bonaldi

Mol Cell Proteomics· July 2024

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Multiscale modeling uncovers 7q11.23 copy number variation-dependent changes in ribosomal biogenesis and neuronal maturation and excitability.
Marija Mihailovich, Pierre-Luc Germain, Reinald Shyti, Davide Pozzi, Roberta Noberini, Tiziana Bonaldi

J Clin Invest· July 2024

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Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells.
Dalia Rosano, Emre Sofyali, Heena Dhiman, Chiara Ghirardi, Diana Ivanoiu, Tiziana Bonaldi

Cancer Discov· May 2024

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Hyperacetylated histone H4 is a source of carbon contributing to lipid synthesis.
Evelina Charidemou, Roberta Noberini, Chiara Ghirardi, Polymnia Georgiou, Panayiota Marcou, Tiziana Bonaldi

EMBO J· April 2024

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Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Marta Russo, Francesco Gualdrini, Veronica Vallelonga, Elena Prosperini, Roberta Noberini, Tiziana Bonaldi

Mol Cell· March 2024

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Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Alice Cortesi, Francesco Gandolfi, Fabiana Arco, Pierluigi Di Chiaro, Emanuele Valli, Tiziana Bonaldi

Sci Adv· March 2024

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Mass Spectrometry-Based Profiling of Histone Post-Translational Modifications in Uveal Melanoma Tissues, Human Melanocytes, and Uveal Melanoma Cell Lines - A Pilot Study.
Martina C Herwig-Carl, Amit Sharma, Verena Tischler, Natalie Pelusi, Karin U Loeffler, Tiziana Bonaldi

Invest Ophthalmol Vis Sci· February 2024

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Proteomics contributions to epigenetic drug discovery.
Roberta Noberini, Tiziana Bonaldi

Proteomics· December 2023

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dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders.
Alejandro López-Tobón, Reinald Shyti, Carlo Emanuele Villa, Cristina Cheroni, Patricio Fuentes-Bravo, Tiziana Bonaldi

Sci Adv· December 2023

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Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome.
Roberto Giambruno, Elsa Zacco, Camilla Ugolini, Andrea Vandelli, Logan Mulroney, Tiziana Bonaldi

Mol Ther Nucleic Acids· December 2023

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Multi-omics integrative modelling for stereotactic body radiotherapy in early-stage non-small cell lung cancer: clinical trial protocol of the MONDRIAN study.
Stefania Volpe, Mattia Zaffaroni, Gaia Piperno, Maria Giulia Vincini, Maria Alessia Zerella, Tiziana Bonaldi

BMC Cancer· December 2023

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A comprehensive characterisation of phaeochromocytoma and paraganglioma tumours through histone protein profiling, DNA methylation and transcriptomic analysis genome wide.
Prodromos Chatzikyriakou, Dimitria Brempou, Mark Quinn, Lauren Fishbein, Roberta Noberini, Tiziana Bonaldi

Clin Epigenetics· December 2023

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Mass Spectrometry-Based Analysis of Histone Posttranslational Modifications from Laser Microdissected Samples.
Roberta Noberini, Tiziana Bonaldi

Methods Mol Biol· September 2023

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