Publications by authors named "Todd Gehr"

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Acid ceramidase as a novel target for adiponectin receptor agonist to abrogate podocyte NLRP3 inflammasome activation and glomerular inflammation during obesity.
Guangbi Li, Dandan Huang, Jason M Kidd, Yao Zou, Xiaoyuan Wu, Todd W B Gehr

J Pharmacol Exp Ther· October 2025

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Podocyte-specific silencing of acid sphingomyelinase gene to abrogate hyperhomocysteinemia-induced NLRP3 inflammasome activation and glomerular inflammation.
Dandan Huang, Jason M Kidd, Yao Zou, Xiaoyuan Wu, Ningjun Li, Todd W B Gehr

Am J Physiol Renal Physiol· June 2024

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Regulation of NLRP3 Inflammasome Activation and Inflammatory Exosome Release in Podocytes by Acid Sphingomyelinase During Obesity.
Dandan Huang, Jason M Kidd, Yao Zou, Xiaoyuan Wu, Todd W B Gehr

Inflammation· October 2023

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Impaired autophagic flux and dedifferentiation in podocytes lacking Asah1 gene: Role of lysosomal TRPML1 channel.
Guangbi Li, Dandan Huang, Yao Zou, Jason Kidd, Todd W B Gehr

Biochim Biophys Acta Mol Cell Res· January 2023

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Cerebral Salt-Wasting Syndrome in a Patient With Active Pulmonary Tuberculosis.
Waqas Memon, Ayesha Akram, Karishma Popli, James B Spriggs, Sana Rehman, Todd Gehr

Cureus· January 2022

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Podocyte Sphingolipid Signaling in Nephrotic Syndrome.
Guangbi Li, Jason Kidd, Todd W B Gehr, Pin-Lan Li

Cell Physiol Biochem· April 2021

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Abnormal podocyte TRPML1 channel activity and exosome release in mice with podocyte-specific Asah1 gene deletion.
Guangbi Li, Dandan Huang, Owais M Bhat, Justin L Poklis, Aolin Zhang, Todd W B Gehr

Biochim Biophys Acta Mol Cell Biol Lipids· February 2021

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Podocytopathy and Nephrotic Syndrome in Mice with Podocyte-Specific Deletion of the Asah1 Gene: Role of Ceramide Accumulation in Glomeruli.
Guangbi Li, Jason Kidd, Cristin Kaspar, Sara Dempsey, Owais M Bhat, Todd W B Gehr

Am J Pathol· June 2020

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Ultra-short duration direct acting antiviral prophylaxis to prevent virus transmission from hepatitis C viremic donors to hepatitis C negative kidney transplant recipients.
Gaurav Gupta, Idris Yakubu, Chandra S Bhati, Yiran Zhang, Le Kang, Todd Gehr

Am J Transplant· March 2020

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Impaired Delivery of Cholesterol Effluxed From Macrophages to Hepatocytes by Serum From CKD Patients May Underlie Increased Cardiovascular Disease Risk.
Graham T Gipson, Salvatore Carbone, Jing Wang, Dave L Dixon, Ion S Jovin, Todd W Gehr

Kidney Int Rep· February 2020

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Sodium butyrate ameliorates insulin resistance and renal failure in CKD rats by modulating intestinal permeability and mucin expression.
Austin Gonzalez, Richard Krieg, Hugh D Massey, Daniel Carl, Shobha Ghosh, Todd W B Gehr

Nephrol Dial Transplant· May 2019

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Curcumin-mediated regulation of intestinal barrier function: The mechanism underlying its beneficial effects.
Siddhartha S Ghosh, Hongliang He, Jing Wang, Todd W Gehr, Shobha Ghosh

Tissue Barriers· January 2018

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Use of Diuretics in the Treatment of Heart Failure in Older Adults.
Domenic A Sica, Todd W B Gehr, William H Frishman

Heart Fail Clin· July 2017

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Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice.
Min Xia, Justine M Abais, Saisudha Koka, Nan Meng, Todd W Gehr

Kidney Blood Press Res· January 2017

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Sphingolipids in obesity and related complications.
Krishna M Boini, Min Xia, Saisudha Koka, Todd W B Gehr, Pin-Lan Li

Front Biosci (Landmark Ed)· January 2017

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High Fat High Cholesterol Diet (Western Diet) Aggravates Atherosclerosis, Hyperglycemia and Renal Failure in Nephrectomized LDL Receptor Knockout Mice: Role of Intestine Derived Lipopolysaccharide.
Siddhartha S Ghosh, Samuel Righi, Richard Krieg, Le Kang, Daniel Carl, Todd W B Gehr

PLoS One· June 2016

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A model of acute kidney injury in mice with cirrhosis and infection.
Daniel E Carl, Siddhartha S Ghosh, Todd W B Gehr, Antonio Abbate, Stefano Toldo

Liver Int· June 2016

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Pre-transplant phospholipase A2 receptor autoantibody concentration is associated with clinically significant recurrence of membranous nephropathy post-kidney transplantation.
Gaurav Gupta, Hasan Fattah, Rivka Ayalon, Jason Kidd, Todd Gehr

Clin Transplant· April 2016

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Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene.
Krishna M Boini, Min Xia, Saisudha Koka, Todd W Gehr, Pin-Lan Li

Oncotarget· April 2016

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Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: role of p62/Sequestosome 1 as a signaling hub.
Guangbi Li, Cai-Xia Li, Min Xia, Joseph K Ritter, Todd W B Gehr

Cell Physiol Biochem· December 2015

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Differences in coagulation in clotting of vascular access in hemodialysis patients.
Chinedu Nweke, Erika Martin, Todd Gehr, Donald Brophy, Daniel Carl

Hemodial Int· April 2015

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Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia.
Justine M Abais, Min Xia, Guangbi Li, Yang Chen, Sabena M Conley, Todd W B Gehr

J Biol Chem· September 2014

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Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing.
Krishna M Boini, Min Xia, Justin M Abais, Guangbi Li, Ashley L Pitzer, Todd W B Gehr

Biochim Biophys Acta· May 2014

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Silencing of hypoxia-inducible factor-1α gene attenuates chronic ischemic renal injury in two-kidney, one-clip rats.
Zhengchao Wang, Qing Zhu, Pin-Lan Li, Romesh Dhaduk, Fan Zhang, Todd W Gehr

Am J Physiol Renal Physiol· May 2014

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