Publications by authors named "Todd Leff"

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Inactivation of Cops5 in Smooth Muscle Cells Causes Abnormal Reproductive Hormone Homeostasis and Development in Mice.
Qian Huang, Yonghong Man, Wei Li, Qi Zhou, Shuo Yuan, Todd Leff

Endocrinology· April 2023

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Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress.
Ruta Jog, Guohua Chen, Jian Wang, Todd Leff

Physiol Rep· August 2021

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Adiponectin secretion from cardiomyocytes produces canonical multimers and partial co-localization with calsequestrin in junctional SR.
Joanna Solarewicz, Amanda Manly, Stephanie Kokoszka, Naama Sleiman, Todd Leff

Mol Cell Biochem· July 2019

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Diabetes and Exposure to Environmental Lead (Pb).
Todd Leff, Paul Stemmer, Jannifer Tyrrell, Ruta Jog

Toxics· September 2018

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Lead (Pb) exposure promotes diabetes in obese rodents.
Jannifer B Tyrrell, Samar Hafida, Paul Stemmer, Angie Adhami, Todd Leff

J Trace Elem Med Biol· January 2017

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PPARγ mutations, lipodystrophy and diabetes.
Olga Astapova, Todd Leff

Horm Mol Biol Clin Investig· November 2014

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Adiponectin and PPARγ: cooperative and interdependent actions of two key regulators of metabolism.
Olga Astapova, Todd Leff

Vitam Horm· February 2013

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Alterations in lipid signaling underlie lipodystrophy secondary to AGPAT2 mutations.
Angela R Subauste, Arun K Das, Xiangquan Li, Brandon G Elliott, Charles Evans, Todd Leff

Diabetes· November 2012

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Clinical and molecular characterization of a severe form of partial lipodystrophy expanding the phenotype of PPARγ deficiency.
Philippe M Campeau, Olga Astapova, Rebecca Martins, Jean Bergeron, Patrick Couture, Todd Leff

J Lipid Res· September 2012

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Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply.
Emilio P Mottillo, Ainsley E Bloch, Todd Leff, James G Granneman

J Biol Chem· July 2012

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PER2 controls lipid metabolism by direct regulation of PPARγ.
Benedetto Grimaldi, Marina Maria Bellet, Sayako Katada, Giuseppe Astarita, Jun Hirayama, Todd Leff

Cell Metab· November 2010

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Endogenously produced adiponectin protects cardiomyocytes from hypertrophy by a PPARgamma-dependent autocrine mechanism.
Rajesh H Amin, Suresh T Mathews, Adebisi Alli, Todd Leff

Am J Physiol Heart Circ Physiol· September 2010

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Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution.
Yun-Hee Youm, Hyunwon Yang, Raj Amin, Steven R Smith, Todd Leff

Aging Cell· August 2010

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Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance.
Rajesh H Amin, Suresh T Mathews, Heidi S Camp, Liyun Ding, Todd Leff

Am J Physiol Endocrinol Metab· January 2010

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Curcumin is not a ligand for peroxisome proliferator-activated receptor-γ.
Venkata R Narala, Monica R Smith, Ravi K Adapala, Rajesh Ranga, Kalpana Panati, Todd Leff

Gene Ther Mol Biol· April 2009

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Efficacy and safety of pioglitazone in treatment of a patient with an atypical partial lipodystrophy syndrome.
Gina G Sleilati, Todd Leff, John W Bonnett, Robert A Hegele

Endocr Pract· October 2007

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Familial partial lipodystrophy phenotype resulting from a single-base mutation in deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma.
Houshang Monajemi, Lin Zhang, Gang Li, Ellen H Jeninga, Henian Cao, Todd Leff

J Clin Endocrinol Metab· May 2007

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Altered promoter recycling rates contribute to dominant-negative activity of human peroxisome proliferator-activated receptor-gamma mutations associated with diabetes.
Gang Li, Todd Leff

Mol Endocrinol· April 2007

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Peroxisomal proliferator activated receptor-gamma deficiency in a Canadian kindred with familial partial lipodystrophy type 3 (FPLD3).
Gordon A Francis, Gang Li, Robin Casey, Jian Wang, Henian Cao, Todd Leff

BMC Med Genet· January 2006

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Review: peroxisome proliferator-activated receptor-gamma and its role in the development and treatment of diabetes.
Todd Leff, Suresh T Mathews, Heidi S Camp

Exp Diabesity Res· January 2005

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Unbuckling lipodystrophy from insulin resistance and hypertension.
Robert A Hegele, Todd Leff

J Clin Invest· July 2004

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Deactivation of murine alveolar macrophages by peroxisome proliferator-activated receptor-gamma ligands.
Raju C Reddy, Venkateshwar G Keshamouni, Shamsul H Jaigirdar, Xianying Zeng, Todd Leff

Am J Physiol Lung Cell Mol Physiol· March 2004

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AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability.
Yu Holly Hong, Usha S Varanasi, Wenbo Yang, Todd Leff

J Biol Chem· July 2003

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PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy.
Robert A Hegele, Henian Cao, Christy Frankowski, Suresh T Mathews, Todd Leff

Diabetes· December 2002

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Adipogenesis and fat-cell function in obesity and diabetes.
Heidi S Camp, Delin Ren, Todd Leff

Trends Mol Med· September 2002

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