Publications by authors named "Todd Markowski"

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Proteomic and metabolomic profiling nominates druggable targets and biomarkers for pulmonary arterial hypertension-associated myopathy and exercise intolerance in male monocrotaline rats.
Phablo Abreu, Ryan Moon, Jenna B Mendelson, Todd Markowski, LeeAnn Higgins

J Heart Lung Transplant· November 2025

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GP130 Antagonism Enhances Porcine RV Function.
Jenna B Mendelson, Jacob D Sternbach, Minwoo Kim, Ryan A Moon, Lynn M Hartweck, Todd Markowski

Circ Res· October 2025

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Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy.
Madelyn J Blake, Jason Hong, Adam Brownstein, Christopher J Rhodes, Jeffrey C Blake, Todd Markowski

bioRxiv· September 2025

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Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs.
Kelley Kilpatrick, Jonah N Cullen, Farah F Almeer, LeeAnn Higgins, Todd Markowski

J Vet Intern Med· June 2025

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The Role of Membrane-Bound Extracellular Vesicles During Co-Stimulation and Conjugation in the Ciliate .
Eric S Cole, Oleksandr Dmytrenko, Mark Li, Neetij Krishnan, Josh Thorp, Todd Markowski

Microorganisms· April 2025

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Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs.
Felipe Kazmirczak, Ryan Moon, Neal T Vogel, Walt Tollison, Matt T Lahti, Todd Markowski

Am J Respir Crit Care Med· March 2025

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Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension-Associated Myopathy and Exercise Intolerance.
Phablo Abreu, Ryan Moon, Jenna B Mendelson, Todd Markowski, LeeAnn Higgins

bioRxiv· March 2025

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Multi-omic Evaluations Nominate an ER-Mitochondrial Axis and Inflammatory Macrophage as Drivers of Right Atrial Dysfunction.
Jenna B Mendelson, Jacob D Sternbach, Jeffrey C Blake, Minwoo Kim, Ryan A Moon, Todd Markowski

bioRxiv· March 2025

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Glycoprotein 130 Antagonism Counteracts Metabolic and Inflammatory Alterations to Enhance Right Ventricle Function in Pulmonary Artery Banded Pigs.
Jenna B Mendelson, Jacob D Sternbach, Ryan A Moon, Lynn M Hartweck, Sophia R Clark, Todd Markowski

bioRxiv· January 2025

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Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension.
Felipe Kazmirczak, Neal T Vogel, Sasha Z Prisco, Michael T Patterson, Jeffrey Annis, Todd Markowski

Circ Res· November 2024

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Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs.
Felipe Kazmirczak, Ryan Moon, Neal T Vogel, Walt Tollison, Matt T Lahti, Todd Markowski

bioRxiv· October 2024

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Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension.
Felipe Kazmirczak, Neal T Vogel, Sasha Z Prisco, Michael T Patterson, Jeffrey Annis, Todd Markowski

bioRxiv· September 2024

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Improved detection of DNA replication fork-associated proteins.
Rebecca S Rivard, Ya-Chu Chang, Ryan L Ragland, Yee-Mon Thu, Muzaffer Kassab, Todd M Markowski

Cell Rep· May 2024

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Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells.
Dongmei Chen, Keith M Wirth, Scott Kizy, Joseph M Muretta, Todd W Markowski

Mol Cancer Res· August 2023

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Natural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice.
Mina P Peyton, Tzu-Yi Yang, LeeAnn Higgins, Todd W Markowski, Kevin Murray

Aging (Albany NY)· August 2023

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Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism.
Charles P Najt, Santosh Adhikari, Timothy D Heden, Wenqi Cui, Erica R Gansemer, Todd W Markowski

Cell Rep· May 2023

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An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples.
Danielle O Weise, Monica E Kruk, LeeAnn Higgins, Todd W Markowski, Pratik D Jagtap

Clin Proteomics· April 2023

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Metabolic and Metabolomic Effects of Metformin in Murine Model of Pulmonary Adenoma Formation.
Andrew C Elton, Vannesa Cedarstrom, Arman Quraishi, Beverly Wuertz, Kevin Murray, Todd W Markowski

Nutr Cancer· March 2023

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Tandem mass tag proteomic and untargeted metabolomic profiling reveals altered serum and CSF biochemical datasets in iron deficient monkeys.
Brian J Sandri, Jonathan Kim, Gabriele R Lubach, Eric F Lock, Candace Guerrero, Todd W Markowski

Data Brief· December 2022

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Global phosphoproteomic profiling of skeletal muscle in ovarian hormone-deficient mice.
Mina P Peyton, Tzu-Yi Yang, LeeAnn Higgins, Todd W Markowski, Cha Vue

Physiol Genomics· November 2022

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Multiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia.
Brian J Sandri, Jonathan Kim, Gabriele R Lubach, Eric F Lock, Candace Guerrero, Todd W Markowski

Am J Physiol Regul Integr Comp Physiol· June 2022

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Multiomics Approach Reveals an Important Role of BNIP3 in Myocardial Remodeling and the Pathogenesis of Heart Failure with Reduced Ejection Fraction.
Antoine H Chaanine, LeeAnn Higgins, Lothar Lauterboeck, Todd Markowski, Qinglin Yang

Cells· May 2022

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Glycoprotein nonmetastatic melanoma protein B (GNMPB) as a novel biomarker for cerebral adrenoleukodystrophy.
Leyla A Taghizadeh, Carina J King, David R Nascene, Ashish O Gupta, Paul J Orchard, Todd W Markowski

Sci Rep· May 2022

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Multi-Omics Approach Profiling Metabolic Remodeling in Early Systolic Dysfunction and in Overt Systolic Heart Failure.
Antoine H Chaanine, LeeAnn Higgins, Todd Markowski, Jarrod Harman, Maureen Kachman

Int J Mol Sci· December 2021

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Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice.
Rebecca R Goldblum, Mark McClellan, Kyle White, Samuel J Gonzalez, Brian R Thompson, Todd W Markowski

Dev Cell· August 2021

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