Publications by authors named "Tohru Abe"

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Expanding the Diversity of the Terpene Skeleton and Structure through Identification of Noncanonical Class IE and IF Terpene Synthase-Formed Products.
Tohru Abe, Tohru Taniguchi, Daijiro Ueda, Takashi Abe, Tsutomu Sato

Org Lett· June 2025

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Isolation and structural determination of natural products bearing tetrahydrogenated isoprenoid side-chains at their ω-termini.
Tohru Abe, Miyu Katano, Ikiru Otsuka, Nozomi Wakamatsu, Saya Takahashi

Org Biomol Chem· April 2025

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Structural-model-based genome mining can efficiently discover novel non-canonical terpene synthases hidden in genomes of diverse species.
Tohru Abe, Haruna Shiratori, Kosuke Kashiwazaki, Kazuma Hiasa, Daijiro Ueda, Takashi Abe

Chem Sci· July 2024

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Identification and functional/structural analyses of large terpene synthases.
Daijiro Ueda, Tohru Abe, Masahiro Fujihashi, Tsutomu Sato

Methods Enzymol· June 2024

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Analysis of vitamin D receptor binding affinities of enzymatically synthesized triterpenes including ambrein and unnatural onoceroids.
Daijiro Ueda, Natsu Matsuda, Yuka Takaba, Nami Hirai, Mao Inoue, Tohru Abe

Sci Rep· January 2024

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Identification and functional analysis of a new type of Z,E-mixed prenyl reductase from mycobacteria.
Tohru Abe, Mariko Hakamata, Akihito Nishiyama, Yoshitaka Tateishi, Sohkichi Matsumoto

FEBS J· August 2022

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Insight into Isoprenoid Biosynthesis by Functional Analysis of Isoprenyl Diphosphate Synthases from Mycobacterium vanbaalenii and Mycobacterium tuberculosis.
Tohru Abe, Sadamu Ozaki, Daijiro Ueda, Tsutomu Sato

Chembiochem· October 2020

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Adduct Formation of Delamanid with NAD in Mycobacteria.
Mikayo Hayashi, Akihito Nishiyama, Ryuki Kitamoto, Yoshitaka Tateishi, Mayuko Osada-Oka, Tohru Abe

Antimicrob Agents Chemother· April 2020

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High titers of both rheumatoid factor and anti-CCP antibodies at baseline in patients with rheumatoid arthritis are associated with increased circulating baseline TNF level, low drug levels, and reduced clinical responses: a post hoc analysis of the RISING study.
Tsutomu Takeuchi, Nobuyuki Miyasaka, Takashi Inui, Toshiro Yano, Toru Yoshinari, Tohru Abe

Arthritis Res Ther· September 2017

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Prediction of clinical response after 1 year of infliximab therapy in rheumatoid arthritis based on disease activity at 3 months: posthoc analysis of the RISING study.
Tsutomu Takeuchi, Nobuyuki Miyasaka, Takashi Inui, Toshiro Yano, Toru Yoshinari, Tohru Abe

J Rheumatol· April 2015

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Stratifying the risk of lymph node metastasis in undifferentiated-type early gastric cancer.
Yukiko Asakawa, Masahiko Ohtaka, Shinya Maekawa, Mitsuharu Fukasawa, Yasuhiro Nakayama, Tohru Abe

World J Gastroenterol· March 2015

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Phase III, multicenter, open-label, long-term study of the safety of abatacept in Japanese patients with rheumatoid arthritis and an inadequate response to conventional or biologic disease-modifying antirheumatic drugs.
Tsutomu Takeuchi, Tsukasa Matsubara, Yukitomo Urata, Eiichi Suematsu, Shuji Ohta, Tohru Abe

Mod Rheumatol· September 2014

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Tolerability and efficacy of abatacept in Japanese patients with rheumatoid arthritis: a phase I study.
Tsukasa Matsubara, Seizo Yamana, Shigeto Tohma, Tsutomu Takeuchi, Hirobumi Kondo, Tohru Abe

Mod Rheumatol· July 2013

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Phase II dose-response study of abatacept in Japanese patients with active rheumatoid arthritis with an inadequate response to methotrexate.
Tsutomu Takeuchi, Tsukasa Matsubara, Taisuke Nitobe, Eiichi Suematsu, Syuji Ohta, Tohru Abe

Mod Rheumatol· March 2013

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Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome.
Keiko Yoshimoto, Maiko Tanaka, Masako Kojima, Yumiko Setoyama, Hideto Kameda, Tohru Abe

Arthritis Res Ther· December 2012

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Inhibition of plasma IL-6 in addition to maintenance of an efficacious trough level of infliximab associated with clinical remission in patients with rheumatoid arthritis: analysis of the RISING Study.
Tsutomu Takeuchi, Nobuyuki Miyasaka, Yoshihiko Tatsuki, Toshiro Yano, Toru Yoshinari, Tohru Abe

Ann Rheum Dis· September 2012

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Baseline tumour necrosis factor alpha levels predict the necessity for dose escalation of infliximab therapy in patients with rheumatoid arthritis.
Tsutomu Takeuchi, Nobuyuki Miyasaka, Yoshihiko Tatsuki, Toshiro Yano, Toru Yoshinari, Tohru Abe

Ann Rheum Dis· July 2011

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Reduced expression of TCR zeta is involved in the abnormal production of cytokines by peripheral T cells of patients with systemic lupus erythematosus.
Keiko Yoshimoto, Yumiko Setoyama, Kensei Tsuzaka, Tohru Abe, Tsutomu Takeuchi

J Biomed Biotechnol· January 2011

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Impact of trough serum level on radiographic and clinical response to infliximab plus methotrexate in patients with rheumatoid arthritis: results from the RISING study.
Tsutomu Takeuchi, Nobuyuki Miyasaka, Kazuhiko Inoue, Tohru Abe, Takao Koike

Mod Rheumatol· January 2010

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Effect of interleukin-2 on synthesis of B cell activating factor belonging to the tumor necrosis factor family (BAFF) in human peripheral blood mononuclear cells.
Katsuya Suzuki, Yumiko Setoyama, Keiko Yoshimoto, Kensei Tsuzaka, Tohru Abe

Cytokine· October 2008

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Conservative sequences in 3'UTR of TCRzeta mRNA regulate TCRzeta in SLE T cells.
Kensei Tsuzaka, Yuka Itami, Chika Kumazawa, Miyuki Suzuki, Yumiko Setoyama, Tohru Abe

Biochem Biophys Res Commun· March 2008

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Down-regulation of Fas-ligand mRNA in Sjögren's syndrome patients with enlarged exocrine glands.
Kensei Tsuzaka, Yukihiro Matsumoto, Yasumasa Sasaki, Tohru Abe, Kazuo Tsubota

Autoimmunity· November 2007

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Efficacy and safety of iguratimod compared with placebo and salazosulfapyridine in active rheumatoid arthritis: a controlled, multicenter, double-blind, parallel-group study.
Masako Hara, Tohru Abe, Sachiko Sugawara, Yutaka Mizushima, Keiko Hoshi

Mod Rheumatol· April 2007

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Long-term safety study of iguratimod in patients with rheumatoid arthritis.
Masako Hara, Tohru Abe, Sachiko Sugawara, Yutaka Mizushima, Keiko Hoshi

Mod Rheumatol· April 2007

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TCRzeta mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients.
Kensei Tsuzaka, Kyoko Nozaki, Chika Kumazawa, Kiyono Shiraishi, Yumiko Setoyama, Tohru Abe

Springer Semin Immunopathol· October 2006

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