Publications by authors named "Toivo Maimets"

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Baseline AHR expression shapes immune response to pharmacological modulation in PBMCs from pancreatic cancer patients.
Arenida Bartkeviciene, Aldona Jasukaitiene, Inga Zievyte, Sandra Ivanauskiene, Gabija Stachneviciute, Toivo Maimets

Front Immunol· December 2025

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Cancer research and the mainstream of biology.
Toivo Maimets

Front Cell Dev Biol· July 2025

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Loss of aryl hydrocarbon receptor reduces pancreatic tumor growth by increasing immune cell infiltration.
Vinicius Kannen, Ninni E Olafsen, Siddhartha Das, Paolo Giuliana, Fauzia N Izzati, Toivo Maimets

Biochem Pharmacol· June 2025

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Loss of increases type I interferon signalling and reduces pancreatic tumour growth by enhancing immune cell infiltration.
Vinicius Kannen, Marit Rasmussen, Siddhartha Das, Paolo Giuliana, Fauzia N Izzati, Toivo Maimets

Front Immunol· May 2025

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Small-molecule inhibitor BAY synergizes with gemcitabine through AHR inhibition in pancreatic cancer cells.
Darius Stukas, Inga Zievyte, Sandra Ivanauskiene, Gabriele Karvelyte, Aldona Jasukaitiene, Toivo Maimets

Biochem Pharmacol· March 2025

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Discovery and optimisation of pyrazolo[1,5-]pyrimidines as aryl hydrocarbon receptor antagonists.
Raitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets

RSC Med Chem· August 2024

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Association between Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells.
Arenida Bartkeviciene, Aldona Jasukaitiene, Inga Zievyte, Darius Stukas, Sandra Ivanauskiene, Toivo Maimets

Cancers (Basel)· September 2023

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Targeting AHR Increases Pancreatic Cancer Cell Sensitivity to Gemcitabine through the ELAVL1-DCK Pathway.
Darius Stukas, Aldona Jasukaitiene, Arenida Bartkeviciene, Jason Matthews, Toivo Maimets

Int J Mol Sci· August 2023

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Use of PepFect14 and siRNA for Targeted Gene Silencing in Human Embryonic Stem Cells.
Egle-Helene Ervin, Margus Pooga, Toivo Maimets

Methods Mol Biol· January 2022

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Colon cancer cell differentiation by sodium butyrate modulates metabolic plasticity of Caco-2 cells via alteration of phosphotransfer network.
Ljudmila Klepinina, Aleksandr Klepinin, Laura Truu, Vladimir Chekulayev, Heiki Vija, Toivo Maimets

PLoS One· June 2021

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Impact of AHR Ligand TCDD on Human Embryonic Stem Cells and Early Differentiation.
Indrek Teino, Antti Matvere, Martin Pook, Inge Varik, Laura Pajusaar, Toivo Maimets

Int J Mol Sci· November 2020

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Utilising FGF2, IGF2 and FSH in serum-free protocol for long-term in vitro cultivation of primary human granulosa cells.
Kati Hensen, Martin Pook, Anu Sikut, Tõnis Org, Toivo Maimets

Mol Cell Endocrinol· June 2020

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miR-10a-5p is increased in atopic dermatitis and has capacity to inhibit keratinocyte proliferation.
Helen Vaher, Toomas Runnel, Egon Urgard, Alar Aab, Gemma Carreras Badosa, Toivo Maimets

Allergy· November 2019

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FSH/LH-Dependent Upregulation of Ahr in Murine Granulosa Cells Is Controlled by PKA Signaling and Involves Epigenetic Regulation.
Antti Matvere, Indrek Teino, Inge Varik, Sulev Kuuse, Tarmo Tiido, Toivo Maimets

Int J Mol Sci· June 2019

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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14.
Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Toivo Maimets

Stem Cell Res Ther· January 2019

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The role of integrin β1 in the heterogeneity of human embryonic stem cells culture.
Ade Kallas-Kivi, Annika Trei, Artjom Stepanjuk, Katrin Ruisu, Keiu Kask, Toivo Maimets

Biol Open· November 2018

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2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells.
Lyudmila Ounpuu, Aleksandr Klepinin, Martin Pook, Indrek Teino, Nadezda Peet, Toivo Maimets

Biochim Biophys Acta Gen Subj· August 2017

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Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis.
Egon Urgard, Annely Lorents, Mariliis Klaas, Kärt Padari, Janeli Viil, Toivo Maimets

J Control Release· August 2016

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Lovastatin Decreases the Expression of CD133 and Influences the Differentiation Potential of Human Embryonic Stem Cells.
Ade Kallas-Kivi, Annika Trei, Toivo Maimets

Stem Cells Int· June 2016

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Changes in Laminin Expression Pattern during Early Differentiation of Human Embryonic Stem Cells.
Martin Pook, Indrek Teino, Ade Kallas, Toivo Maimets, Sulev Ingerpuu

PLoS One· May 2016

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Assessment of the Potential of CDK2 Inhibitor NU6140 to Influence the Expression of Pluripotency Markers NANOG, OCT4, and SOX2 in 2102Ep and H9 Cells.
Ade Kallas, Martin Pook, Annika Trei, Toivo Maimets

Int J Cell Biol· December 2014

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SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate.
Ade Kallas, Martin Pook, Annika Trei, Toivo Maimets

Stem Cells Int· April 2014

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Transcriptional repression of the Ahr gene by LHCGR signaling in preovulatory granulosa cells is controlled by chromatin accessibility.
Indrek Teino, Antti Matvere, Sulev Kuuse, Sulev Ingerpuu, Toivo Maimets

Mol Cell Endocrinol· January 2014

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Leukocyte marker CD43 promotes cell growth in co-operation with β-catenin in non-hematopoietic cancer cells.
Anna Balikova, Kersti Jääger, Janeli Viil, Toivo Maimets, Lilian Kadaja-Saarepuu

Int J Oncol· July 2012

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The aryl hydrocarbon receptor regulates mouse Fshr promoter activity through an e-box binding site.
Indrek Teino, Sulev Kuuse, Sulev Ingerpuu, Toivo Maimets, Tarmo Tiido

Biol Reprod· March 2012

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