Publications by authors named "Tom Boone"

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Longevity factor klotho enhances cognition in aged nonhuman primates.
Stacy A Castner, Shweta Gupta, Dan Wang, Arturo J Moreno, Cana Park, Tom Boone

Nat Aging· August 2023

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Discovery of the Migraine Prevention Therapeutic Aimovig (Erenumab), the First FDA-Approved Antibody against a G-Protein-Coupled Receptor.
Chadwick Terence King, Colin V Gegg, Sylvia Nai-Yu Hu, Hsieng Sen Lu, Brian M Chan, Tom J Boone

ACS Pharmacol Transl Sci· December 2019

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Peptibodies: A flexible alternative format to antibodies.
Grant Shimamoto, Colin Gegg, Tom Boone, Christophe Quéva

MAbs· January 2013

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A novel modality of BAFF-specific inhibitor AMG623 peptibody reduces B-cell number and improves outcomes in murine models of autoimmune disease.
Hailing Hsu, Sanjay D Khare, Frances Lee, Kent Miner, Yi-Ling Hu, Tom Boone

Clin Exp Rheumatol· July 2012

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Context-dependent role of angiopoietin-1 inhibition in the suppression of angiogenesis and tumor growth: implications for AMG 386, an angiopoietin-1/2-neutralizing peptibody.
Angela Coxon, James Bready, Hosung Min, Stephen Kaufman, Juan Leal, Tom Boone

Mol Cancer Ther· October 2010

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Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia.
Wei Gu, Hai Yan, Katherine A Winters, Renée Komorowski, Steven Vonderfecht, Tom Boone

J Pharmacol Exp Ther· December 2009

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Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis.
Xiaodong Li, Michael S Ominsky, Kelly S Warmington, Sean Morony, Jianhua Gong, Tom Boone

J Bone Miner Res· April 2009

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Fully human monoclonal antibodies antagonizing the glucagon receptor improve glucose homeostasis in mice and monkeys.
Hai Yan, Wei Gu, Jie Yang, Vivian Bi, Yuqing Shen, Tom Boone

J Pharmacol Exp Ther· April 2009

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Infrequent delivery of a long-acting PTH-Fc fusion protein has potent anabolic effects on cortical and cancellous bone.
Paul J Kostenuik, Serge Ferrari, Dominique Pierroz, Mary Bouxsein, Sean Morony, Tom Boone

J Bone Miner Res· October 2007

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Generation and characterization of monoclonal antibodies to human keratinocyte growth factor receptor.
Ping Wei, Jinghui Zhan, Shuying Liu, David Chang, Raj Haldankar, Tom Boone

Hybridoma (Larchmt)· June 2006

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Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2.
Jonathan Oliner, Hosung Min, Juan Leal, Dongyin Yu, Shashirekha Rao, Tom Boone

Cancer Cell· November 2004

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Epratuzumab, a humanized monoclonal antibody targeting CD22: characterization of in vitro properties.
Josette Carnahan, Paul Wang, Richard Kendall, Ching Chen, Sylvia Hu, Tom Boone

Clin Cancer Res· September 2003

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Essential role of NF-kappa B-inducing kinase in T cell activation through the TCR/CD3 pathway.
Mitsuru Matsumoto, Takuji Yamada, Steven K Yoshinaga, Tom Boone, Tom Horan

J Immunol· August 2002

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