Publications by authors named "Tom Huang"

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Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor Immunosuppression.
Jared T Moore, Hiroyuki Kawai, Brian R Blank, Kejia Wu, Chien-Hung Yeh, Tom Huang

J Med Chem· November 2025

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Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation.
Dax Calder, Farshad Oveissi, Simin Maleknia, Tom Huang, Bernard Koong

Adv Healthc Mater· May 2025

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Surgical peri-implantitis treatment with and without guided bone regeneration. A randomized controlled trial.
Lisa J A Heitz-Mayfield, Fritz Heitz, Bernard Koong, Tom Huang, Paola Chivers

Clin Oral Implants Res· September 2023

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Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor.
Shruti Lal, Neil E Bhola, Bee-Chun Sun, Yuping Chen, Tom Huang

Cancer Res Commun· September 2023

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Targeted Literature Review of the Burden of Respiratory Syncytial Infection among High-Risk and Elderly Patients in Asia Pacific Region.
Daisuke Kurai, JoonYoung Song, Yhu-Chering Huang, Zhijun Jie, Petar Atanasov, Tom Hsun-Wei Huang

Infect Dis Ther· March 2023

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Persistence and adherence to second-generation antipsychotic long-acting injectable medications for schizophrenia: A comparative study in the Australian context.
Nagesh Pai, Andrew B McGeachie, Andrea Puig, Tom H-W Huang, Prachi Brahmbhatt

Australas Psychiatry· February 2023

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CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy.
Anthony Cao, Jiaqing Yi, Xinyan Tang, Christopher W Szeto, Renyi Wu, Tom Huang

Cancer Res Commun· November 2022

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ZL-1211 Exhibits Robust Antitumor Activity by Enhancing ADCC and Activating NK Cell-mediated Inflammation in CLDN18.2-High and -Low Expressing Gastric Cancer Models.
Hiroyasu Konno, Tracey Lin, Renyi Wu, Xinchuan Dai, Shou Li, Tom Huang

Cancer Res Commun· September 2022

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An Australian Real-World Study of Treatment Persistence of Ustekinumab in Crohn's Disease.
Tzu Hsiang Chien, Andrea Puig, Thang Khuong, Mahsa H Kouhkamari, Samuel Che, Tom Hsun-Wei Huang

Biologics· June 2021

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Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine Production.
Xiaohui Du, Jared Moore, Brian R Blank, John Eksterowicz, Dena Sutimantanapi, Tom Huang

J Med Chem· September 2020

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Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633).
Xiaohui Du, John Eksterowicz, Haiying Zhou, Yosup Rew, Liusheng Zhu, Tom Huang

J Med Chem· July 2019

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In vivo morphologic comparison of saphenous vein grafts and native coronary arteries following non-ST elevation myocardial infarction.
Tom Hsun-Wei Huang, Kalpa De Silva, Usaid K Allahwala, Edward J Danson, Pasi K Karjalainen

Cardiovasc Revasc Med· January 2019

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Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101).
Yosup Rew, Xiaohui Du, John Eksterowicz, Haiying Zhou, Nadine Jahchan, Tom Huang, Elizabeth Huang

J Med Chem· September 2018

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High-resolution Temporal Representations of Alcohol and Tobacco Behaviors from Social Media Data.
Tom Huang, Anas Elghafari, Kunal Relia, Rumi Chunara

Proc ACM Hum Comput Interact· November 2017

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New-to-nature sophorose analog: a potent inducer for gene expression in Trichoderma reesei.
Tom Tao Huang, John M Wages

Enzyme Microb Technol· April 2016

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Management of cardiorenal metabolic syndrome in diabetes mellitus: a phytotherapeutic perspective.
Min Kyong Song, Neal M Davies, Basil D Roufogalis, Tom Hsun-Wei Huang

J Diabetes Res· October 2014

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Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning.
Guifen Xu, Jiyun S Chen, Ruta Phadnis, Tom Huang, Craig Uyeda

Bioanalysis· August 2012

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Healing the diabetic heart: modulation of cardiometabolic syndrome through peroxisome proliferator activated receptors (PPARs).
Tom Hsun-Wei Huang, Basil D Roufogalis

Curr Mol Pharmacol· June 2012

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Determining between chyle leak and anastomotic leak after esophageal reconstruction: the utility of methylene blue dye.
Shivam Kapila, Warren M Rozen, Tom Huang, Terry Wu, Sian Fairbank

Laryngoscope· April 2012

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Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR-γ-related pharmacology.
Min K Song, Basil D Roufogalis, Tom H W Huang

Br J Pharmacol· January 2012

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Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit.
Matthew L Brown, Wade Aaron, Richard J Austin, Angela Chong, Tom Huang

Bioorg Med Chem Lett· September 2011

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Acne - best practice management.
David Cook, George Krassas, Tom Huang

Aust Fam Physician· September 2010

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Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.
Jacob A Kaizerman, Wade Aaron, Songzhu An, Richard Austin, Matt Brown, Tom Huang

Bioorg Med Chem Lett· August 2010

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Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists.
Brian S Lucas, Wade Aaron, Songzhu An, Richard J Austin, Matthew Brown, Tom Huang

Bioorg Med Chem Lett· June 2010

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Investigation of collision-induced dissociations involving odd-electron ion formation under positive electrospray ionization conditions using accurate mass.
Guifen Xu, Tom Huang, Jennifer Zhang, Jennifer K Huang, Timothy Carlson

Rapid Commun Mass Spectrom· February 2010

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