Publications by authors named "Tom Lee"

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A novel CD3ε fusion receptor allows T cell engager use in TCR-less allogeneic CAR T cells to improve activity and prevent antigen escape.
Dan Lu, Hui-Yi Chu, Soo Park, Mark Landon, Masanao Tsuda, Tom Lee

Mol Ther· September 2025

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Toggling of NKG2A expression drives functional specialization of iPSC-derived CAR NK cells.
Minoru Kanaya, Camille Philippon, Herman Netskar, Michelle Lu Saetersmoen, Artur Cieslar-Pobuda, Tom Lee

bioRxiv· August 2025

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Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy.
Martin P Hosking, Soheila Shirinbak, Kyla Omilusik, Shilpi Chandra, Mika K Kaneko, Tom T Lee

Cell Stem Cell· July 2025

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iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors.
Bi-Huei Yang, Alma Gutierrez, Angela Liao, Soheila Shirinbak, Bjoern Gaertner, Tom Lee

Cell Rep Med· July 2025

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Quantifying the cost savings and health impacts of improving colonoscopy quality: an economic evaluation.
Stephen McCarthy, Matthew David Rutter, Peter McMeekin, Jamie Catlow, Linda Sharp, Tom Lee

BMJ Qual Saf· June 2025

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Author Correction: Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells.
Sjoukje J C van der Stegen, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Tom Lee

Nat Biomed Eng· November 2024

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Polyp detection with colonoscopy assisted by the GI Genius artificial intelligence endoscopy module compared with standard colonoscopy in routine colonoscopy practice (COLO-DETECT): a multicentre, open-label, parallel-arm, pragmatic randomised controlled trial.
Alexander Seager, Linda Sharp, Laura J Neilson, Andrew Brand, James S Hampton, Tom J W Lee

Lancet Gastroenterol Hepatol· October 2024

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Scrapping the two child benefit cap would immediately reduce poverty while investing in the future.
Tom Lee,

BMJ· October 2024

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Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies.
Quirin Hammer, Karlo Perica, Rina M Mbofung, Hanna van Ooijen, Karen E Martin, Tom Lee

Cell Stem Cell· September 2024

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A chemical approach facilitates CRISPRa-only human iPSC generation and minimizes the number of targeted loci required.
Ramzey Abujarour, Jason Dinella, Mochtar Pribadi, Lauren K Fong, Matthew Denholtz, Tom T Lee

Future Sci OA· May 2024

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Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells.
Quirin Hammer, Karlo Perica, Hanna van Ooijen, Rina Mbofung, Pouria Momayyezi, Tom Lee

bioRxiv· October 2023

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A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors.
John Goulding, Wen-I Yeh, Bryan Hancock, Robert Blum, Tianhao Xu, Tom T Lee

Med· July 2023

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Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
Meigen Yu, Hui Ye, Ruth B De-Paula, Carl Grant Mangleburg, Timothy Wu, Tom V Lee

PLoS Genet· May 2023

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Atomic-scale origin of the low grain-boundary resistance in perovskite solid electrolyte LiSrTaZrO.
Tom Lee, Ji Qi, Chaitanya A Gadre, Huaixun Huyan, Shu-Ting Ko

Nat Commun· April 2023

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Investigating attitudes and insights into the global warming impact of inhalers.
Matthew J Woodall, John Ma, Kate Emett, Amelia P E Hamblin, Katie Knowles, Tom Hyunwoo Lee

N Z Med J· April 2023

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Dual antigen-targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia.
Frank Cichocki, Jodie P Goodridge, Ryan Bjordahl, Sajid Mahmood, Zachary B Davis, Tom T Lee

Blood· December 2022

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Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells.
Sjoukje J C van der Stegen, Pieter L Lindenbergh, Roseanna M Petrovic, Hongyao Xie, Mame P Diop, Tom Lee

Nat Biomed Eng· November 2022

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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Frank Cichocki, Ryan Bjordahl, Jodie P Goodridge, Sajid Mahmood, Svetlana Gaidarova, Tom T Lee

Nat Commun· November 2022

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Trial protocol for COLO-DETECT: A randomized controlled trial of lesion detection comparing colonoscopy assisted by the GI Genius™ artificial intelligence endoscopy module with standard colonoscopy.
Alexander Seager, Linda Sharp, James S Hampton, Laura J Neilson, Tom J W Lee

Colorectal Dis· October 2022

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Detection of Microsatellite Instability in Colonoscopic Biopsies and Postal Urine Samples from Lynch Syndrome Cancer Patients Using a Multiplex PCR Assay.
Rachel Phelps, Richard Gallon, Christine Hayes, Eli Glover, Philip Gibson, Tom Lee

Cancers (Basel)· August 2022

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Toll-9 interacts with Toll-1 to mediate a feedback loop during apoptosis-induced proliferation in Drosophila.
Alicia Shields, Alla Amcheslavsky, Elizabeth Brown, Tom V Lee, Yingchao Nie

Cell Rep· May 2022

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Metasurface wavefront control for high-performance user-natural augmented reality waveguide glasses.
Hyunpil Boo, Yoo Seung Lee, Hangbo Yang, Brian Matthews, Tom G Lee

Sci Rep· April 2022

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Use of Capillary Aerosol Generator in Continuous Production of Controlled Aerosol for Non-Clinical Studies.
Didier Goedertier, Sandra Schorderet Weber, Francesco Lucci, Tom Lee, Wei Teck Tan

J Vis Exp· April 2022

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Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy.
Karrune V Woan, Hansol Kim, Ryan Bjordahl, Zachary B Davis, Svetlana Gaidarova, Tom T Lee

Cell Stem Cell· December 2021

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Implementing and Sustaining Early Cancer Diagnosis Initiatives in Canada: An Exploratory Qualitative Study.
Christine Fahim, Larkin Davenport Huyer, Tom Taehoon Lee, Anubha Prashad, Robyn Leonard

Curr Oncol· October 2021

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