Publications by authors named "Tomas Blom"

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LAPTM4B Confers Resistance to EGFR-TKIs by Suppressing the Proteasomal Degradation of ATP1A1 in Non-small Cell Lung Cancer.
Dan Liu, Minxia Liu, Dongjin Lv, Yuxiang Li, Hongjuan Guo, Tomas Blom

Int J Biol Sci· December 2025

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LAPTM4B counteracts ferroptosis via suppressing the ubiquitin-proteasome degradation of SLC7A11 in non-small cell lung cancer.
Ruyu Yan, Dan Liu, Hongjuan Guo, Minxia Liu, Dongjin Lv, Benny Björkblom, Tomas Blom

Cell Death Dis· June 2024

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miR-137-LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma.
Ruyu Yan, Dan Liu, Junjie Wang, Minxia Liu, Hongjuan Guo, Tomas Blom

Oncogenesis· May 2023

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Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane.
Henrik Nurmi, Anders P E Backman, Josefin Halin, Max Lönnfors, Tomas Blom

J Biol Chem· April 2023

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LAPTM4B controls the sphingolipid and ether lipid signature of small extracellular vesicles.
Andrea Dichlberger, Kecheng Zhou, Nils Bäck, Thomas Nyholm, Anders Backman, Tomas Blom

Biochim Biophys Acta Mol Cell Biol Lipids· February 2021

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Lysosome Associated Protein Transmembrane 4B-24 Is the Predominant Protein Isoform in Human Tissues and Undergoes Rapid, Nutrient-Regulated Turnover.
Kecheng Zhou, Andrea Dichlberger, Elina Ikonen, Tomas Blom

Am J Pathol· October 2020

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A Ceramide-Regulated Element in the Late Endosomal Protein LAPTM4B Controls Amino Acid Transporter Interaction.
Kecheng Zhou, Andrea Dichlberger, Hector Martinez-Seara, Thomas K M Nyholm, Shiqian Li, Tomas Blom

ACS Cent Sci· May 2018

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Induced Pluripotent Stem Cells Derived from a CLN5 Patient Manifest Phenotypic Characteristics of Neuronal Ceroid Lipofuscinoses.
Kristiina Uusi-Rauva, Tea Blom, Carina von Schantz-Fant, Tomas Blom, Anu Jalanko

Int J Mol Sci· May 2017

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Lipoprotein-mediated delivery of BODIPY-labeled sterol and sphingolipid analogs reveals lipid transport mechanisms in mammalian cells.
Elina Ikonen, Tomas Blom

Chem Phys Lipids· January 2016

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Trafficking and Functions of Bioactive Sphingolipids: Lessons from Cells and Model Membranes.
Kecheng Zhou, Tomas Blom

Lipid Insights· December 2015

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LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.
Tomas Blom, Shiqian Li, Andrea Dichlberger, Nils Bäck, Young Ah Kim

Nat Chem Biol· October 2015

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A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca²⁺ microdomain in the caveolar compartment.
Ilari Pulli, Tomas Blom, Christoffer Löf, Melissa Magnusson, Alessandro Rimessi

Biochim Biophys Acta· September 2015

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LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route.
Kristiina Kanerva, Riikka-Liisa Uronen, Tomas Blom, Shiqian Li, Robert Bittman

Dev Cell· November 2013

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NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation.
Vilja Pietiäinen, Boris Vassilev, Tomas Blom, Wei Wang, Jessica Nelson

J Cell Sci· September 2013

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Lipid-protein interactions: finding the perfect match.
Tomas Blom, Elina Ikonen

Curr Opin Lipidol· December 2012

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Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case.
Tomas Blom, Zaiguo Li, Robert Bittman, Pentti Somerharju, Elina Ikonen

Traffic· September 2012

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Cln5-deficiency in mice leads to microglial activation, defective myelination and changes in lipid metabolism.
Mia-Lisa Schmiedt, Tea Blom, Tomas Blom, Outi Kopra, Andrew Wong

Neurobiol Dis· April 2012

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Synthesis and biosynthetic trafficking of membrane lipids.
Tomas Blom, Pentti Somerharju, Elina Ikonen

Cold Spring Harb Perspect Biol· August 2011

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An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.
Tomas Blom, Nina Bergelin, Annika Meinander, Christoffer Löf, J Peter Slotte

BMC Cell Biol· June 2010

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FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.
Tomas Blom, Nils Bäck, Aino-Liisa Mutka, Robert Bittman, Zaiguo Li

Circ Res· March 2010

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Overexpression of TRPC3 reduces the content of intracellular calcium stores in HEK-293 cells.
Christoffer Löf, Tomas Blom, Kid Törnquist

J Cell Physiol· July 2008

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Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase.
Emad Afrasiabi, Tomas Blom, Sonja Balthasar, Kid Törnquist

Mol Cell Endocrinol· August 2007

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Sphingosylphosphorylcholine enhances calcium entry in thyroid FRO cells by a mechanism dependent on protein kinase C.
Emad Afrasiabi, Tomas Blom, Elina Ekokoski, Raimo K Tuominen, Kid Törnquist

Cell Signal· October 2006

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Batten disease (JNCL) is linked to disturbances in mitochondrial, cytoskeletal, and synaptic compartments.
Kaisu Luiro, Outi Kopra, Tomas Blom, Massimiliano Gentile, Hannah M Mitchison

J Neurosci Res· October 2006

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Sphingosine kinase regulates voltage operated calcium channels in GH4C1 rat pituitary cells.
Tomas Blom, Nina Bergelin, J Peter Slotte, Kid Törnquist

Cell Signal· September 2006

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