Publications by authors named "Tomas Gonec"

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Insight into antistaphylococcal effect of chlorinated 1-hydroxynaphthalene-2-carboxanilides.
Lucia Vrablova, Tomas Gonec, Petra Majerova, Andrej Kovac, Dominika Kos

ADMET DMPK· March 2025

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Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides.
Lucia Vrablova, Tomas Gonec, Tereza Kauerova, Michal Oravec, Izabela Jendrzejewska

ADMET DMPK· February 2025

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Trifluoromethylcinnamanilides - Effective dual inhibitors of Mycobacterium smegmatis and Plasmodium falciparum.
Jiri Kos, Tomas Strharsky, Rodrigo Tosso, Lucas Gutierrez, Dominika Kos, Tomas Gonec

Bioorg Chem· January 2025

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Towards Arginase Inhibition: Hybrid SAR Protocol for Property Mapping of Chlorinated -arylcinnamamides.
Andrzej Bak, Jiri Kos, Gilles Degotte, Aleksandra Swietlicka, Tomas Strharsky, Tomas Gonec

Int J Mol Sci· February 2023

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Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections.
Tomas Strharsky, Dominika Pindjakova, Jiri Kos, Lucia Vrablova, Pavel Smak, Tomas Gonec

Int J Mol Sci· December 2022

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Insights into Antimalarial Activity of -Phenyl-Substituted Cinnamanilides.
Jiri Kos, Gilles Degotte, Dominika Pindjakova, Tomas Strharsky, Timotej Jankech, Tomas Gonec

Molecules· November 2022

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Antistaphylococcal Activities and ADME-Related Properties of Chlorinated Arylcarbamoylnaphthalenylcarbamates.
Tomas Gonec, Dominika Pindjakova, Lucia Vrablova, Tomas Strharsky, Hana Michnova

Pharmaceuticals (Basel)· June 2022

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Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity.
Tereza Padrtová, Pavlína Marvanová, Renáta Kubínová, Jozef Csöllei, Oldřich Farsa

Curr Org Synth· September 2021

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Photosynthesis-Inhibiting Activity of -(Disubstituted-phenyl)-3-hydroxynaphthalene-2-carboxamides.
Jiri Kos, Tomas Gonec, Michal Oravec, Izabela Jendrzejewska, Josef Jampilek

Molecules· July 2021

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Hydroxynaphthalenecarboxamides and substituted piperazinylpropandiols, two new series of BRAF inhibitors. A theoretical and experimental study.
Ludmila E Campos, Francisco Garibotto, Emilio Angelina, Jiri Kos, Tomas Gonec

Bioorg Chem· October 2020

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Consensus-Based Pharmacophore Mapping for New Set of -(disubstituted-phenyl)-3-hydroxyl-naphthalene-2-carboxamides.
Andrzej Bak, Jiri Kos, Hana Michnova, Tomas Gonec, Sarka Pospisilova

Int J Mol Sci· September 2020

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Ring-Substituted 1-Hydroxynaphthalene-2-Carboxanilides Inhibit Proliferation and Trigger Mitochondria-Mediated Apoptosis.
Tereza Kauerová, Tomáš Goněc, Josef Jampílek, Susanne Hafner, Ann-Kathrin Gaiser

Int J Mol Sci· May 2020

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Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques.
Ludmila E Campos, Francisco M Garibotto, Emilio Angelina, Jiri Kos, Tihomir Tomašič, Tomas Gonec

Bioorg Chem· October 2019

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Bioactivity of Methoxylated and Methylated 1-Hydroxynaphthalene-2-Carboxanilides: Comparative Molecular Surface Analysis.
Hana Michnová, Šárka Pospíšilová, Tomáš Goněc, Iva Kapustíková, Peter Kollár

Molecules· August 2019

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Design and synthesis of anticancer 1-hydroxynaphthalene-2-carboxanilides with a p53 independent mechanism of action.
Ewelina Spaczyńska, Anna Mrozek-Wilczkiewicz, Katarzyna Malarz, Jiri Kos, Tomas Gonec

Sci Rep· April 2019

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Investigation of Hydro-Lipophilic Properties of -Alkoxyphenylhydroxynaphthalenecarboxamides †.
Iva Kapustikova, Andrzej Bak, Tomas Gonec, Jiri Kos, Violetta Kozik

Molecules· July 2018

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Synthesis and In Vitro Antimycobacterial Activity of Novel N-Arylpiperazines Containing an Ethane-1,2-diyl Connecting Chain.
Tomáš Goněc, Ivan Malík, Jozef Csöllei, Josef Jampílek, Jiřina Stolaříková

Molecules· November 2017

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An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors.
Marcela Vettorazzi, Emilio Angelina, Santiago Lima, Tomas Gonec, Jan Otevrel

Eur J Med Chem· October 2017

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Halogenated 1-Hydroxynaphthalene-2-Carboxanilides Affecting Photosynthetic Electron Transport in Photosystem II.
Tomas Gonec, Jiri Kos, Matus Pesko, Jana Dohanosova, Michal Oravec

Molecules· October 2017

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Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates.
Tomas Gonec, Josef Stranik, Matus Pesko, Jiri Kos, Michal Oravec

Molecules· July 2017

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Antimycobacterial N-alkoxyphenylhydroxynaphthalenecarboxamides affecting photosystem II.
Tomas Gonec, Katarina Kralova, Matus Pesko, Josef Jampilek

Bioorg Med Chem Lett· May 2017

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Synthesis and Antimicrobial Evaluation of 1-[(2-Substituted phenyl)carbamoyl]naphthalen-2-yl Carbamates.
Tomas Gonec, Sarka Pospisilova, Lucie Holanova, Josef Stranik, Aneta Cernikova

Molecules· September 2016

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N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity.
Tomas Gonec, Sarka Pospisilova, Tereza Kauerova, Jiri Kos, Jana Dohanosova

Molecules· August 2016

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Antiproliferative and Pro-Apoptotic Effect of Novel Nitro-Substituted Hydroxynaphthanilides on Human Cancer Cell Lines.
Tereza Kauerova, Jiri Kos, Tomas Gonec, Josef Jampilek, Peter Kollar

Int J Mol Sci· July 2016

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Ring-substituted 8-hydroxyquinoline-2-carboxanilides as potential antimycobacterial agents.
Jiri Kos, Iveta Zadrazilova, Eoghan Nevin, Michal Soral, Tomas Gonec

Bioorg Med Chem· August 2015

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