Publications by authors named "Tomas Jacso"

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MTA-cooperative PRMT5 inhibitors from cofactor-directed DNA-encoded library screens.
Jan Andersson, Sanne Cowland, Mikkel Vestergaard, Yajing Yang, Siyuan Liu, Tomas Jacso

Proc Natl Acad Sci U S A· May 2025

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From DNA-Encoded Library Screening to : An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo Efficacy.
Ian Sarvary, Mikkel Vestergaard, Loris Moretti, Jan Andersson, Jorge Peiró Cadahía, Tomas Jacso

J Med Chem· March 2025

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Discovery of NSD2-Degraders from Novel and Selective DEL Hits.
Jan LegaardAndersson, Jesper Christensen, Daniela Kleine-Kohlbrecher, Itys Vacher Comet, Jonatan Fullerton Støier, Tomas Jacso

Chembiochem· December 2023

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Discovery and development of substituted thiadiazoles as inhibitors of Staphylococcus aureus Sortase A.
Patrick M Wehrli, Ivana Uzelac, Thomas Olsson, Tomas Jacso, Daniel Tietze

Bioorg Med Chem· October 2019

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AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins.
Maria Saline, Lukas Badertscher, Madita Wolter, Roxanne Lau, Anders Gunnarsson, Tomas Jacso

J Biol Chem· August 2019

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The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.
Tomas Jacso, Benjamin Bardiaux, Jana Broecker, Sebastian Fiedler, Tom Baerwinkel

J Am Chem Soc· December 2013

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Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coli.
Tomas Jacso, Erwin Schneider, Bernd Rupp, Bernd Reif

J Biol Chem· May 2012

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Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.
Tomas Jacso, W Trent Franks, Honor Rose, Uwe Fink, Jana Broecker

Angew Chem Int Ed Engl· January 2012

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Dimer formation of a stabilized Gbeta1 variant: a structural and energetic analysis.
Stephanie Thoms, Klaas E A Max, Michael Wunderlich, Tomas Jacso, Hauke Lilie

J Mol Biol· September 2009

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NMR assignments of the periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter.
Tomas Jacso, Mathias Grote, Peter Schmieder, Erwin Schneider, Bernd Reif

Biomol NMR Assign· June 2009

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Periplasmic loop P2 of the MalF subunit of the maltose ATP binding cassette transporter is sufficient to bind the maltose binding protein MalE.
Tomas Jacso, Mathias Grote, Martin L Daus, Peter Schmieder, Sandro Keller

Biochemistry· March 2009

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