Publications by authors named "Tomas Loja"

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Creatine kinase B, a downstream effector of c-Myb, controls migration of osteosarcoma cells via regulation of N-cadherin.
Jana Pokludová, Petr Lapčík, Iva Staniczková Zambo, Jiří Kohoutek, Danica Zapletalová, Tomáš Loja

Cancer Cell Int· December 2025

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Functional characterization of 16 variants found in the LDL receptor gene.
Kateřina Konečná, Tereza Přerovská, Tomáš Loja, Lenka Fajkusová, Jana Koutná

J Lipid Res· September 2025

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Regulation of Cell-Nanoparticle Interactions through Mechanobiology.
Marco Cassani, Francesco Niro, Soraia Fernandes, Daniel Pereira-Sousa, Sofia Faes Morazzo, Tomas Loja

Nano Lett· February 2025

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Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.
Jan Rynes, Eva Istvankova, Michaela Dzurov Krafcikova, Enrico Luchinat, Letizia Barbieri, Tomas Loja

Commun Biol· February 2025

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A novel thrombocytopenia-4-causing CYCS gene variant decreases caspase activity: Three-generation study.
Jiří Štika, Michaela Pešová, Kateřina Staňo Kozubík, Magdalena Skalníková, Lenka Dostálová, Tomáš Loja

Br J Haematol· December 2024

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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drugs.
Eva Hoferkova, Vaclav Seda, Sona Kadakova, Jan Verner, Tomas Loja

Leukemia· August 2024

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In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells.
Pavlína Víšková, Eva Ištvánková, Jan Ryneš, Šimon Džatko, Tomáš Loja

Nat Commun· March 2024

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Plastic response of macrophages to metal ions and nanoparticles in time mimicking metal implant body environment.
Polina Navratilova, Jan Emmer, Tomas Tomas, Ludek Ryba, Jan Burda, Tomas Loja

Environ Sci Pollut Res Int· January 2024

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CCL2/MCP-1, interleukin-8, and fractalkine/CXC3CL1: Potential biomarkers of epileptogenesis and pharmacoresistance in childhood epilepsy.
Katarína Česká, Jan Papež, Hana Ošlejšková, Ondřej Slabý, Lenka Radová, Tomáš Loja

Eur J Paediatr Neurol· September 2023

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FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.
Vaclav Seda, Eva Vojackova, Laura Ondrisova, Lenka Kostalova, Sonali Sharma, Tomas Loja

Blood· September 2021

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Hierarchical distribution of somatic variants in newly diagnosed chronic myeloid leukaemia at diagnosis and early follow-up.
Marianna Romzova, Dagmar Smitalova, Jakub Hynst, Nikola Tom, Tomas Loja

Br J Haematol· August 2021

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Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro.
Aneta Ledererova, Lenka Dostalova, Veronika Kozlova, Helena Peschelova, Adriana Ladungova, Tomas Loja

J Immunother Cancer· August 2021

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Disruption of NAP1 genes in Arabidopsis thaliana suppresses the fas1 mutant phenotype, enhances genome stability and changes chromatin compaction.
Karolína Kolářová, Martina Nešpor Dadejová, Tomáš Loja, Gabriela Lochmanová, Eva Sýkorová

Plant J· April 2021

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Clonal hierarchy of main molecular lesions in acute myeloid leukaemia.
Zdenka Herudkova, Martin Culen, Adam Folta, Ivana Jeziskova, Jana Cerna, Tomas Loja

Br J Haematol· August 2020

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Low Density Lipoprotein Receptor Variants in the Beta-Propeller Subdomain and Their Functional Impact.
Lucie Dušková, Lucie Nohelová, Tomáš Loja, Jana Fialová, Petra Zapletalová

Front Genet· June 2020

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Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia.
Veronika Mancikova, Helena Peschelova, Veronika Kozlova, Aneta Ledererova, Adriana Ladungova, Tomas Loja

J Immunother Cancer· March 2020

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Monitoring DNA-Ligand Interactions in Living Human Cells Using NMR Spectroscopy.
Michaela Krafcikova, Simon Dzatko, Coralie Caron, Anton Granzhan, Radovan Fiala, Tomas Loja

J Am Chem Soc· August 2019

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Activation-induced deaminase and its splice variants associate with trisomy 12 in chronic lymphocytic leukemia.
Kristina Zaprazna, Kamila Reblova, Veronika Svobodova, Lenka Radova, Vojtech Bystry, Tomas Loja

Ann Hematol· February 2019

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The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice.
Martin Culen, Zdenka Kosarova, Ivana Jeziskova, Adam Folta, Jana Chovancova, Tomas Loja

J Cancer Res Clin Oncol· July 2018

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Evaluation of the Stability of DNA i-Motifs in the Nuclei of Living Mammalian Cells.
Simon Dzatko, Michaela Krafcikova, Robert Hänsel-Hertsch, Tomas Fessl, Radovan Fiala, Tomas Loja

Angew Chem Int Ed Engl· February 2018

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Co-Expression of Cancer Stem Cell Markers Corresponds to a Pro-Tumorigenic Expression Profile in Pancreatic Adenocarcinoma.
Jan Skoda, Marketa Hermanova, Tomas Loja, Pavel Nemec, Jakub Neradil

PLoS One· July 2017

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Global MicroRNA Expression Profiling Identifies Unique MicroRNA Pattern of Radioresistant Glioblastoma Cells.
Jakub Ondracek, Pavel Fadrus, Jiri Sana, Andrej Besse, Tomas Loja

Anticancer Res· March 2017

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Ability to downregulate the level of cyclin-dependent kinase inhibitor p27 after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway.
Leona Raskova Kafkova, Veronika Navrkalova, Marie Jarosova, Tomas Loja, Jana Chovancova

Leuk Lymphoma· January 2017

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Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission.
Pavithra Shyamsunder, Milan Esner, Maunish Barvalia, Yu Jun Wu, Tomáš Loja

Oncotarget· September 2016

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Cancer stem cell markers in pediatric sarcomas: Sox2 is associated with tumorigenicity in immunodeficient mice.
Jan Skoda, Alena Nunukova, Tomas Loja, Iva Zambo, Jakub Neradil

Tumour Biol· July 2016

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