Publications by authors named "Tomomitsu Doi"

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Caspase-4 deficiency impairs nuclear actin-mediated DNA double-strand break repair and increases radiosensitivity in cancer cells.
Shohei Nagasaka, Tomomitsu Doi, Kunie Obayashi, Masaoki Kohzaki, Kazuhiro Sumida

Biochem Biophys Res Commun· November 2025

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Differential Induction of Endoplasmic Reticulum Stress Signaling by Antibody Isotypes: Implications for Plasma Cell Differentiation.
Kunie Obayashi, Tomomitsu Doi, Kazuhiro Sumida, Motoyoshi Endo

Eur J Immunol· April 2025

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Caspase-4 promotes metastasis and interferon-γ-induced pyroptosis in lung adenocarcinoma.
Yosuke Chiba, Tomomitsu Doi, Kunie Obayashi, Kazuhiro Sumida, Shohei Nagasaka

Commun Biol· June 2024

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Caspase-4 has a role in cell division in epithelial cells through actin depolymerization.
Kazuhiro Sumida, Tomomitsu Doi, Kunie Obayashi, Yosuke Chiba, Shohei Nagasaka

Biochem Biophys Res Commun· February 2024

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ANGPTL8 links inflammation and poor differentiation, which are characteristics of malignant renal cell carcinoma.
Takuo Matsukawa, Tomomitsu Doi, Kunie Obayashi, Kazuhiro Sumida, Naohiro Fujimoto

Cancer Sci· April 2023

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Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells.
Tomomitsu Doi, Hironori Hojo, Shinsuke Ohba, Kunie Obayashi, Motoyoshi Endo

Heliyon· February 2022

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Angiopoietin-like protein 2 decreases peritoneal metastasis of ovarian cancer cells by suppressing anoikis resistance.
Yuko Takeshita, Takeshi Motohara, Tsuyoshi Kadomatsu, Tomomitsu Doi, Kunie Obayashi

Biochem Biophys Res Commun· July 2021

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Soluble PD-L1 with PD-1-binding capacity exists in the plasma of patients with non-small cell lung cancer.
Masahiro Takeuchi, Tomomitsu Doi, Kunie Obayashi, Ayako Hirai, Kazue Yoneda

Immunol Lett· April 2018

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Measles virus induces persistent infection by autoregulation of viral replication.
Tomomitsu Doi, Hyun-Jeong Kwon, Tomoyuki Honda, Hiroki Sato, Misako Yoneda

Sci Rep· November 2016

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CCR9+ macrophages are required for eradication of peritoneal bacterial infections and prevention of polymicrobial sepsis.
Takahiro Mizukami, Takanori Kanai, Yohei Mikami, Atsushi Hayashi, Tomomitsu Doi

Immunol Lett· September 2012

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IgA plasma cells express the negative regulatory co-stimulatory molecule programmed cell death 1 ligand and have a potential tolerogenic role in the intestine.
Tomomitsu Doi, Takanori Kanai, Yohei Mikami, Tomohisa Sujino, Li Jun

Biochem Biophys Res Commun· September 2012

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Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes.
Lucia Kato, Nasim A Begum, A Maxwell Burroughs, Tomomitsu Doi, Jun Kawai

Proc Natl Acad Sci U S A· February 2012

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Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells.
Tomohisa Sujino, Takanori Kanai, Yuichi Ono, Yohei Mikami, Atsushi Hayashi, Tomomitsu Doi

Gastroenterology· September 2011

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AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.
Maki Kobayashi, Masatoshi Aida, Hitoshi Nagaoka, Nasim A Begum, Yoko Kitawaki, Tomomitsu Doi

Proc Natl Acad Sci U S A· December 2009

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Molecular mechanism for generation of antibody memory.
Velizar Shivarov, Reiko Shinkura, Tomomitsu Doi, Nasim A Begum, Hitoshi Nagaoka

Philos Trans R Soc Lond B Biol Sci· March 2009

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Carboxy-terminal domain of AID required for its mRNA complex formation in vivo.
Taichiro Nonaka, Tomomitsu Doi, Takae Toyoshima, Masamichi Muramatsu, Tasuku Honjo

Proc Natl Acad Sci U S A· February 2009

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Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.
Nasim A Begum, Andre Stanlie, Tomomitsu Doi, Yoko Sasaki, Hai Wei Jin

Proc Natl Acad Sci U S A· February 2009

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The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination.
Tomomitsu Doi, Lucia Kato, Satomi Ito, Reiko Shinkura, Min Wei

Proc Natl Acad Sci U S A· February 2009

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PI3K is a negative regulator of IgE production.
Tomomitsu Doi, Kunie Obayashi, Takashi Kadowaki, Hideki Fujii, Shigeo Koyasu

Int Immunol· April 2008

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Dendritic cells suppress IgE production in B cells.
Kunie Obayashi, Tomomitsu Doi, Shigeo Koyasu

Int Immunol· February 2007

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The p85alpha regulatory subunit of class IA phosphoinositide 3-kinase regulates beta-selection in thymocyte development.
Fumiko Shiroki, Satoshi Matsuda, Tomomitsu Doi, Mari Fujiwara, Yoshito Mochizuki

J Immunol· February 2007

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De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination.
Tomomitsu Doi, Kazuo Kinoshita, Masaya Ikegawa, Masamichi Muramatsu, Tasuku Honjo

Proc Natl Acad Sci U S A· March 2003

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