Publications by authors named "Tomoyoshi Soga"

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Context-Specific Metabolic Alterations in HPRT1 Knockout Cells Within a 3D Culture System.
Sho Tabata, Ichiro Fujimoto, Tomoyoshi Soga, Hideki Makinoshima

Cancer Med· December 2025

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Longitudinal study of plasma metabolites during menopause and their associations with later onset of metabolic syndrome.
Atsuko Miyake, Miho Iida, Sei Harada, Daisuke Sugiyama, Minako Matsumoto, Tomoyoshi Soga

J Clin Endocrinol Metab· December 2025

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Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions.
Takumi Mikawa, Masahiro Kameda, Sumiko Ikari, Eri Shibata, Shuyu Liu, Tomoyoshi Soga

Signal Transduct Target Ther· December 2025

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Guanine nucleotides drive ribosome biogenesis and glycolytic reprogramming in acute myeloid leukemia stem cells.
Gentaro Kawano, Riichiro Ikeda, Daisuke Ishihara, Takahiro Shima, Teppei Sakoda, Tomoyoshi Soga

Blood· November 2025

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Decreased Fecal Nicotinamide and Increased Bacterial Nicotinamidase Gene Expression in Ulcerative Colitis Patients.
Keiya Aoyama, Ryodai Yamamura, Takehiko Katsurada, Tomohiro Shimizu, Daisuke Takahashi, Tomoyoshi Soga

Inflamm Bowel Dis· October 2025

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EML4-ALK Rearrangement Creates a Distinctive Myeloid Cell-Dominant Immunosuppressive Microenvironment in Lung Cancer.
Kosuke Arai, Yukari Nishito, Hideaki Mizuno, Noriko Motoi, Nobuyoshi Hiraoka, Tomoyoshi Soga

Cancer Immunol Res· September 2025

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Dysregulated Anaerobic Glycolysis in Podocytes is Relevant to the Progression of Focal Segmental Glomerulosclerosis.
Masahiro Sugimura, Kayaho Maeda, Katsuaki Shibata, Hiroshi Seko, Yohei Kozaki, Tomoyoshi Soga

Kidney Int Rep· September 2025

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Glucose-activated JMJD1A drives visceral adipogenesis via α-ketoglutarate-dependent chromatin remodeling.
Chenxu Yang, Makoto Arai, Eko Fuji Ariyanto, Ji Zhang, Debby Mirani Lubis, Tomoyoshi Soga

Cell Rep· August 2025

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2,3-Pyridinedicarboxylate Is Associated with Shorter Recurrence-Free Survival in Patients with Hypopharyngeal Squamous Cell Carcinoma.
Hiroki Takase, Takao Fujisawa, Ryuichi Hayashi, Hideki Makinoshima, Yutaka Suzuki, Tomoyoshi Soga

Pathobiology· August 2025

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Lubiprostone in chronic kidney disease: Insights into mitochondrial function and polyamines from a randomized phase 2 clinical trial.
Shun Watanabe, Masaaki Nakayama, Takashi Yokoo, Satoru Sanada, Yoshifumi Ubara, Tomoyoshi Soga

Sci Adv· August 2025

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Mitochondria-Homing Drug Mitochonic Acid 5 Improves Barth Syndrome Myopathy in a Human-Induced Pluripotent Stem Cell Model and Barth Syndrome Drosophila Model.
Yoshiyasu Tongu, Tomoko Kasahara, Tetsuro Matsuhashi, Yoshitsugu Oikawa, Ryota Akimoto, Tomoyoshi Soga

FASEB J· June 2025

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Dietary amino acids regulate Salmonella colonization via microbiota-dependent mechanisms in the mouse gut.
Joseph M Pickard, Steffen Porwollik, Gustavo Caballero-Flores, Roberta Caruso, Shinji Fukuda, Tomoyoshi Soga

Nat Commun· May 2025

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Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma.
Yongwei Jing, Masahiko Kobayashi, Mahmoud I Shoulkamy, Meiqi Zhou, Ha Thi Vu, Tomoyoshi Soga

Nat Commun· April 2025

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MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes.
Miki Nishio, Keiko Yamaguchi, Junji Otani, Katsuya Yuguchi, Daisuke Kohno, Tomoyoshi Soga

Proc Natl Acad Sci U S A· April 2025

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Structural robustness and temporal vulnerability of the starvation-responsive metabolic network in healthy and obese mouse liver.
Keigo Morita, Atsushi Hatano, Toshiya Kokaji, Hikaru Sugimoto, Takaho Tsuchiya, Tomoyoshi Soga

Sci Signal· April 2025

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Genome-wide association study of plasma amino acids and Mendelian randomization for cardiometabolic traits.
Ryota Toki, Sotaro Fushiki, Shun Kojima, Yoichi Sutoh, Yayoi Otsuka-Yamasaki, Tomoyoshi Soga

Sci Rep· April 2025

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PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover.
Takashi Ono, Yoshitaka Taketomi, Takayoshi Higashi, Hiroyasu Sato, Chika Mochizuki-Ono, Tomoyoshi Soga

Nat Commun· March 2025

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Dynamics of the gut microbiome in FAP patients undergoing intensive endoscopic reduction of polyp burden.
Sayaka Mizutani, Ayako Tamaki, Satoshi Shiba, Felix Salim, Masayoshi Yamada, Tomoyoshi Soga

Gut· January 2025

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Gut microbial factors predict disease severity in a mouse model of multiple sclerosis.
Alex Steimle, Mareike Neumann, Erica T Grant, Stéphanie Willieme, Alessandro De Sciscio, Tomoyoshi Soga

Nat Microbiol· September 2024

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The role of cytidine 5'-triphosphate synthetase 1 in metabolic rewiring during epithelial-to-mesenchymal transition in non-small-cell lung cancer.
Fumie Nakasuka, Akiyoshi Hirayama, Hideki Makinoshima, Seiji Yano, Tomoyoshi Soga

FEBS Open Bio· September 2024

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FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells.
Shuko Miyahara, Mai Ohuchi, Miyuki Nomura, Eifumi Hashimoto, Tomoyoshi Soga

J Biol Chem· September 2024

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A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.
Masaya Ueno, Hiroki Sugiyama, Feng Li, Tatsuya Nishimura, Hiroshi Arakawa, Tomoyoshi Soga

Anal Chem· September 2024

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Time and dose selective glucose metabolism for glucose homeostasis and energy conversion in the liver.
Yifei Pan, Atsushi Hatano, Satoshi Ohno, Keigo Morita, Toshiya Kokaji, Tomoyoshi Soga

NPJ Syst Biol Appl· September 2024

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Prognostic Significance of F-FDG PET/CT and Tumor Metabolic Changes in Patients With Pancreatic Ductal Adenocarcinoma.
Ayaka Shimomura, Minoru Oshima, Hironobu Suto, Hiroyuki Matsukawa, Akihiro Kondo, Tomoyoshi Soga

Anticancer Res· August 2024

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species are distinctly associated with patients with Lynch syndrome colorectal cancer.
Felix Salim, Sayaka Mizutani, Satoshi Shiba, Hiroyuki Takamaru, Masayoshi Yamada, Tomoyoshi Soga

iScience· July 2024

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