Publications by authors named "Tongju Guan"

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Molecular mechanisms limiting the AAV gene therapy treatment window in mouse models of blue cone monochromacy.
Brooke A Brothers, Emily R Sechrest, Li Ma, Madyson E Ashcraft, Tongju Guan

Commun Biol· November 2025

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Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments.
Alexis Crockett, Sierra Kuzak, Thamaraiselvi Saravanan, Tongju Guan, Tamara Caspary

J Neurosci· August 2025

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Molecular Mechanisms Limiting the Therapeutic Window of AAV Gene Therapy in Mouse Models of Blue Cone Monochromacy.
Wen-Tao Deng, Brooke Brothers, Emily Sechrest, Li Ma, Madyson Ashcraft, Tongju Guan

Res Sq· April 2025

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Molecular Mechanisms Limiting the Therapeutic Window of AAV Gene Therapy in Mouse Models of Blue Cone Monochromacy.
Brooke A Brothers, Emily R Sechrest, Li Ma, Madyson Ashcraft, Tongju Guan

bioRxiv· February 2025

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Aberrant lipid accumulation and retinal pigment epithelium dysfunction in PRCD-deficient mice.
Sree I Motipally, Douglas R Kolson, Tongju Guan, Saravanan Kolandaivelu

Exp Eye Res· September 2024

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TUBB4B is essential for the cytoskeletal architecture of cochlear supporting cells and motile cilia development.
Urikhan Sanzhaeva, Helen Boyd-Pratt, Philip T R Bender, Thamaraiselvi Saravanan, Scott B Rhodes, Tongju Guan

Commun Biol· September 2024

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Aberrant lipid accumulation and retinal pigmental epithelium dysfunction in PRCD-deficient mice.
Sree I Motipally, Douglas R Kolson, Tongju Guan, Saravanan Kolandaivelu

bioRxiv· May 2024

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Prominin 1 is crucial for the early development of photoreceptor outer segments.
Sila Yanardag, Scott Rhodes, Thamaraiselvi Saravanan, Tongju Guan, Visvanathan Ramamurthy

Sci Rep· May 2024

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Excessive tubulin glutamylation leads to progressive cone-rod dystrophy and loss of outer segment integrity.
Rawaa Aljammal, Thamaraiselvi Saravanan, Tongju Guan, Scott Rhodes, Michael A Robichaux

Hum Mol Genet· April 2024

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Prenylation is essential for the enrichment of cone phosphodiesterase-6 (PDE6) in outer segments and efficient cone phototransduction.
Faezeh Moakedi, Rawaa Aljammal, Deepak Poria, Thamaraiselvi Saravanan, Scott B Rhodes, Tongju Guan

Hum Mol Genet· August 2023

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HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits.
Daniella Munezero, Hunter Aliff, Ezequiel Salido, Thamaraiselvi Saravanan, Urikhan Sanzhaeva, Tongju Guan

J Biol Chem· June 2023

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Loss of MPC1 reprograms retinal metabolism to impair visual function.
Allison Grenell, Yekai Wang, Michelle Yam, Aditi Swarup, Tanya L Dilan, Tongju Guan

Proc Natl Acad Sci U S A· February 2019

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N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor.
Hao Zhang, Xigang Jing, Yang Shi, Hao Xu, Jianhai Du, Tongju Guan

J Lipid Res· November 2013

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Enoyl coenzyme a hydratase domain-containing 2, a potential novel regulator of myocardial ischemia injury.
Jianhai Du, Zhixin Li, Quan-Zhen Li, Tongju Guan, Qiuhui Yang

J Am Heart Assoc· October 2013

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The protein partners of GTP cyclohydrolase I in rat organs.
Jianhai Du, Ru-Jeng Teng, Matt Lawrence, Tongju Guan, Hao Xu

PLoS One· November 2012

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Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension.
Ru-Jeng Teng, Jianhai Du, Scott Welak, Tongju Guan, Annie Eis

Am J Physiol Lung Cell Mol Physiol· April 2012

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Differential sensitivity to LPS-induced myocardial dysfunction in the isolated brown Norway and Dahl S rat hearts: roles of mitochondrial function, NF-κB activation, and TNF-α production.
Jianzhong An, Jianhai Du, Na Wei, Tongju Guan, Amadou K S Camara

Shock· March 2012

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Role of autophagy in angiogenesis in aortic endothelial cells.
Jianhai Du, Ru-Jeng Teng, Tongju Guan, Annie Eis, Sushma Kaul

Am J Physiol Cell Physiol· January 2012

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Increased resistance to LPS-induced myocardial dysfunction in the Brown Norway rats versus Dahl S rats: roles of inflammatory cytokines and nuclear factor kappaB pathway.
Jianhai Du, Jianzhong An, Na Wei, Tongju Guan, Kirkwood A Pritchard

Shock· March 2010

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Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I.
Jianhai Du, Na Wei, Hao Xu, Ying Ge, Jeannette Vásquez-Vivar, Tongju Guan

Arterioscler Thromb Vasc Biol· December 2009

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Inhibition of CDKS by roscovitine suppressed LPS-induced *NO production through inhibiting NFkappaB activation and BH4 biosynthesis in macrophages.
Jianhai Du, Na Wei, Tongju Guan, Hao Xu, Jianzhong An

Am J Physiol Cell Physiol· September 2009

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Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts.
Jianhai Du, Tongju Guan, Hui Zhang, Yi Xia, Fei Liu

Biochem Biophys Res Commun· April 2008

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AICAR inhibits proliferation and induced S-phase arrest, and promotes apoptosis in CaSki cells.
Tong-ju Guan, Feng-jin Qin, Jian-hai Du, Li Geng, You-yi Zhang

Acta Pharmacol Sin· December 2007

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Phenylarsine oxide inhibited beta-adrenergic receptor-mediated IL-6 secretion: inhibition of cAMP accumulation and CREB activation in cardiac fibroblasts.
Jian-Hai Du, Tong-Ju Guan, Hui Zhang, Han Xiao, Qi-De Han

Biochem Biophys Res Commun· January 2007

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