Publications by authors named "Tongmeng Yan"

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Optimization of siRNA therapeutics targeting MIAT for cardioprotection in myocardial ischemia/reperfusion injury.
Xiao-Rong Ma, Tong-Meng Yan, Yu Pan, Zhi-Hong Jiang

Mol Ther Nucleic Acids· December 2025

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Huang-Lian-Jie-Du decoction enhances Capecitabine-Oxaliplatin efficacy via Akkermansia muciniphila and CD8 T cells in colorectal cancer.
Yan Chen, Xinjie Lai, Yijie Zhang, Cheng Qiu, Ying Qin, Tongmeng Yan, Yuyang Jiang

Phytomedicine· November 2025

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Propiolates-Based Selective Labeling and Affinity Capture Enables High-Fidelity Transcriptome-Wide Profiling of A-to-I RNA Editing.
Jian-Feng Qin, Tong-Meng Yan, Chen Huang, Ying-Wei Wang, Yu Pan, Xiao Yang

Bioconjug Chem· November 2025

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Mitochondrial tRNA-specific Taurine Modifications Correlate With Ferroptosis-associated Myocardial Injury.
Yu Pan, Jin-Jie Hu, Xiao-Rong Ma, Tong-Meng Yan, Zhi-Hong Jiang

J Mol Biol· August 2025

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Targeting NUCKS1 with a fragment of tRNA of Chinese yew for the treatment of colorectal cancer.
Kai-Yue Cao, Da Zhang, Long-Bo Bai, Tong-Meng Yan, Yan Chen, Yu-Yang Jiang

Noncoding RNA Res· April 2025

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Hydroxy-wybutosine tRNA modifications as indicators of disease progression and therapeutic targets in leukaemia.
Xu Chen, Rui-Ze Gong, Liu-Ying Mo, Ya-Ting Cheng, Yu Ma, Tong-Meng Yan

Br J Haematol· February 2025

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Antibiotic-Induced Gut Microbiota Dysbiosis Modulates Host Transcriptome and mA Epitranscriptome via Bile Acid Metabolism.
Meng Yang, Xiaoqi Zheng, Jiajun Fan, Wei Cheng, Tong-Meng Yan

Adv Sci (Weinh)· July 2024

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Hydroxyapatite-based nano-drug delivery system for nicotinamide mononucleotide (NMN): significantly enhancing NMN bioavailability and replenishing in vivo nicotinamide adenine dinucleotide (NAD+) levels.
Da Zhang, Lee-Fong Yau, Long-Bo Bai, Tian-Tian Tong, Kai-Yue Cao, Tong-Meng Yan

J Pharm Pharmacol· December 2023

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Selective Chemical Labeling Strategy for Oligonucleotides Determination: A First Application to Full-Range Profiling of Transfer RNA Modifications.
Hui-Xia Zhang, Jian-Feng Qin, Jian-Feng Sun, Yu Pan, Tong-Meng Yan

Anal Chem· January 2023

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A tRNA-derived fragment of ginseng protects heart against ischemia/reperfusion injury via targeting the lncRNA MIAT/VEGFA pathway.
Kua Hu, Tong-Meng Yan, Kai-Yue Cao, Fang Li, Xiao-Rong Ma

Mol Ther Nucleic Acids· September 2022

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Antitumor Activities of tRNA-Derived Fragments and tRNA Halves from Non-pathogenic Escherichia coli Strains on Colorectal Cancer and Their Structure-Activity Relationship.
Kai-Yue Cao, Yu Pan, Tong-Meng Yan, Peng Tao, Yi Xiao

mSystems· April 2022

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A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting .
Kai-Yue Cao, Tong-Meng Yan, Ji-Zhou Zhang, Ting-Fung Chan, Jie Li

Mol Ther Nucleic Acids· March 2022

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The nature of the modification at position 37 of tRNAPhe correlates with acquired taxol resistance.
Yu Pan, Tong-Meng Yan, Jing-Rong Wang, Zhi-Hong Jiang

Nucleic Acids Res· January 2021

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Full-Range Profiling of tRNA Modifications Using LC-MS/MS at Single-Base Resolution through a Site-Specific Cleavage Strategy.
Tong-Meng Yan, Yu Pan, Meng-Lan Yu, Kua Hu, Kai-Yue Cao

Anal Chem· January 2021

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LC-MS/MS Profiling of Post-Transcriptional Modifications in Ginseng tRNA Purified by a Polysaccharase-Aided Extraction Method.
Tongmeng Yan, Kua Hu, Fei Ren, Zhihong Jiang

Biomolecules· April 2020

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Purification, characterization and cytotoxic activities of individual tRNAs from Escherichia coli.
Kai-Yue Cao, Yu Pan, Tong-Meng Yan, Zhi-Hong Jiang

Int J Biol Macromol· January 2020

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Profiles and Gender-Specifics of UDP-Glucuronosyltransferases and Sulfotransferases Expressions in the Major Metabolic Organs of Wild-Type and Efflux Transporter Knockout FVB Mice.
Jiamei Chen, Haihui Zheng, Sijing Zeng, Cong Xie, Xiaoyan Li, Tongmeng Yan

Mol Pharm· September 2017

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High-Throughput and Reliable Isotope Label-free Approach for Profiling 24 Metabolic Enzymes in FVB Mice and Sex Differences.
Jiamei Chen, Lijun Zhu, Xiaoyan Li, Haihui Zheng, Tongmeng Yan

Drug Metab Dispos· June 2017

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LC-MS/MS quantification of sulfotransferases is better than conventional immunogenic methods in determining human liver SULT activities: implication in precision medicine.
Cong Xie, Tong-Meng Yan, Jia-Mei Chen, Xiao-Yan Li, Juan Zou

Sci Rep· June 2017

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SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats.
Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan

Drug Metab Dispos· March 2016

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Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients.
Tongmeng Yan, Linlin Lu, Cong Xie, Jiamei Chen, Xiaojuan Peng

Mol Cancer Ther· December 2015

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Study of pharmacokinetic profiles and characteristics of active components and their metabolites in rat plasma following oral administration of the water extract of Astragali radix using UPLC-MS/MS.
Jian Shi, Liang Zheng, Zhufen Lin, Chuqi Hou, Wenqin Liu, Tongmeng Yan

J Ethnopharmacol· July 2015

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A combined strategy of mass fragmentation, post-column cobalt complexation and shift in ultraviolet absorption spectra to determine the uridine 5'-diphospho-glucuronosyltransferase metabolism profiling of flavones after oral administration of a flavone mixture in rats.
Qiang Li, Liping Wang, Peimin Dai, Xuejun Zeng, Xiaoxiao Qi, Tongmeng Yan

J Chromatogr A· May 2015

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Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
Tongmeng Yan, Song Gao, Xiaojuan Peng, Jian Shi, Cong Xie

Pharm Res· March 2015

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Sorafenib metabolism is significantly altered in the liver tumor tissue of hepatocellular carcinoma patient.
Ling Ye, Xiaoshan Yang, Enshuang Guo, Weiying Chen, Linlin Lu, Tongmeng Yan, Fuyan Zhou

PLoS One· January 2015

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