Publications by authors named "Tongyu Huo"

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Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation.
Xiaodong Dou, Tongyu Huo, Yameng Liu, Zichen Pang, Lingyu Su

Eur J Med Chem· April 2024

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Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing.
Tongyu Huo, Xinyi Zhao, Zengrui Cheng, Jialiang Wei, Minghui Zhu

Acta Pharm Sin B· March 2024

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Discovery of 3-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin derivatives as SARS-CoV-2 main protease inhibitors through virtual screening and biological evaluation.
Xiaodong Dou, Qi Sun, Yameng Liu, Yangbin Lu, Caifang Zhang, Tongyu Huo

Bioorg Med Chem Lett· January 2024

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Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Jia-Le Wang, Xiao-Dong Dou, Jie Cheng, Ming-Xin Gao, Guo-Feng Xu, Tong-Yu Huo

Nat Metab· October 2023

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Discovery of 2-(furan-2-ylmethylene)hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease.
Xiaodong Dou, Qi Sun, Guofeng Xu, Yameng Liu, Caifang Zhang, Tongyu Huo

Eur J Med Chem· August 2022

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Rh-Catalyzed Reaction of Vinyl Azides with Isonitriles and Alkynes/Benzynes.
Zongyang Li, Tongyu Huo, Li Li, Shuo Feng, Qian Wang

Org Lett· December 2018

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