Publications by authors named "Tony Mertz"

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Defining APOBEC-induced mutation signatures and modifying activities in yeast.
Tony M Mertz, Zachary W Kockler, Margo Coxon, Cameron Cordero, Atri K Raval

Methods Enzymol· April 2025

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APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats.
Rebecca E Brown, Margo Coxon, Benjamin Larsen, Maxwell Allison, Ariana Chadha, Tony M Mertz

Proc Natl Acad Sci U S A· January 2025

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Her2 amplification, Rel-A, and Bach1 can influence APOBEC3A expression in breast cancer cells.
Madeline Dennis, Alyssa Hurley, Nicholas Bray, Cameron Cordero, Jose Ilagan, Tony M Mertz

PLoS Genet· May 2024

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An impaired ubiquitin-proteasome system increases APOBEC3A abundance.
Margo Coxon, Madeline A Dennis, Alexandra Dananberg, Christopher D Collins, Hannah E Wilson, Tony M Mertz

NAR Cancer· December 2023

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Genetic inhibitors of APOBEC3B-induced mutagenesis.
Tony M Mertz, Elizabeth Rice-Reynolds, Ly Nguyen, Anna Wood, Cameron Cordero

Genome Res· September 2023

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Genetic modifiers of APOBEC-induced mutagenesis.
Tony M Mertz, Elizabeth Rice-Reynolds, Ly Nguyen, Anna Wood, Nicholas Bray

bioRxiv· April 2023

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APOBEC-Induced Mutagenesis in Cancer.
Tony M Mertz, Christopher D Collins, Madeline Dennis, Margo Coxon, Steven A Roberts

Annu Rev Genet· November 2022

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The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions.
Braulio Bonilla, Alexander J Brown, Sarah R Hengel, Kyle S Rapchak, Debra Mitchell, Tony M Mertz

Elife· November 2021

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Single-stranded DNA binding proteins influence APOBEC3A substrate preference.
Amber L Brown, Christopher D Collins, Secily Thompson, Margo Coxon, Tony M Mertz

Sci Rep· October 2021

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APOBEC3A is a prominent cytidine deaminase in breast cancer.
Luis M Cortez, Amber L Brown, Madeline A Dennis, Christopher D Collins, Alexander J Brown, Tony M Mertz

PLoS Genet· December 2019

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The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.
Joel C Rosenbaum, Braulio Bonilla, Sarah R Hengel, Tony M Mertz, Benjamin W Herken

Nat Commun· August 2019

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Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity.
Tony M Mertz, Victoria Harcy, Steven A Roberts

Genes (Basel)· January 2017

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APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.
James I Hoopes, Luis M Cortez, Tony M Mertz, Ewa P Malc, Piotr A Mieczkowski

Cell Rep· February 2016

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Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity.
Tony M Mertz, Sushma Sharma, Andrei Chabes, Polina V Shcherbakova

Proc Natl Acad Sci U S A· May 2015

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DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.
Olga V Kochenova, Danielle L Daee, Tony M Mertz, Polina V Shcherbakova

PLoS Genet· March 2015

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DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.
Matthew R Northam, Elizabeth A Moore, Tony M Mertz, Sara K Binz, Carrie M Stith

Nucleic Acids Res· January 2014

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A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability.
Lyudmila Y Kadyrova, Tony M Mertz, Yu Zhang, Matthew R Northam, Ziwei Sheng

PLoS Genet· October 2013

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Histone deacetylase complexes promote trinucleotide repeat expansions.
Kim Debacker, Aisling Frizzell, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz

PLoS Biol· February 2012

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A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.
Danielle L Daee, Tony M Mertz, Polina V Shcherbakova

Proc Natl Acad Sci U S A· January 2010

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Postreplication repair inhibits CAG.CTG repeat expansions in Saccharomyces cerevisiae.
Danielle L Daee, Tony Mertz, Robert S Lahue

Mol Cell Biol· January 2007

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