Publications by authors named "Topaz Altman"

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Muscle-derived miR-126 regulates TDP-43 axonal local synthesis and NMJ integrity in ALS models.
Ariel Ionescu, Lior Ankol, Anand Ganapathy Subramaniam, Topaz Altman, Iddo Magen

Nat Neurosci· November 2025

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Looking for answers far away from the soma-the (un)known axonal functions of TDP-43, and their contribution to early NMJ disruption in ALS.
Ariel Ionescu, Topaz Altman, Eran Perlson

Mol Neurodegener· May 2023

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Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanism.
Bar Cohen, Topaz Altman, Adi Golani-Armon, Anca F Savulescu, Amjd Ibraheem

J Cell Sci· August 2022

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Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.
Topaz Altman, Ariel Ionescu, Amjad Ibraheem, Dominik Priesmann, Tal Gradus-Pery

Nat Commun· November 2021

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A CRMP4-dependent retrograde axon-to-soma death signal in amyotrophic lateral sclerosis.
Roy Maimon, Lior Ankol, Tal Gradus Pery, Topaz Altman, Ariel Ionescu

EMBO J· September 2021

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Neuromuscular junction mitochondrial enrichment: a "double-edged sword" underlying the selective motor neuron vulnerability in amyotrophic lateral sclerosis.
Topaz Altman, Eran Perlson

Neural Regen Res· January 2021

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Axonal Transport of Organelles in Motor Neuron Cultures using Microfluidic Chambers System.
Topaz Altman, Roy Maimon, Ariel Ionescu, Tal Gradus Pery, Eran Perlson

J Vis Exp· May 2020

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An compartmental system underlines the contribution of mitochondrial immobility to the ATP supply in the NMJ.
Topaz Altman, Danielle Geller, Elisabeth Kleeblatt, Tal Gradus-Perry, Eran Perlson

J Cell Sci· December 2019

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Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1 Model.
Ariel Ionescu, Tal Gradus, Topaz Altman, Roy Maimon, Noi Saraf Avraham

Cell Death Dis· March 2019

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Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS.
Noga Gershoni-Emek, Topaz Altman, Ariel Ionescu, Christopher J Costa, Tal Gradus-Pery

Front Mol Neurosci· September 2018

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The receptor tyrosine kinase TrkB signals without dimerization at the plasma membrane.
Eitan Erez Zahavi, Noam Steinberg, Topaz Altman, Michael Chein, Yuvraj Joshi

Sci Signal· May 2018

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ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.
Nimrod Rotem, Iddo Magen, Ariel Ionescu, Noga Gershoni-Emek, Topaz Altman

Sci Rep· March 2017

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