Publications by authors named "Torsten Lowin"

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Fumarate-based drugs protect against neuroinflammation via upregulation of anti-ferroptotic pathways.
Katinka Fischer, Leonie Thewes, Tim Prozorovski, Mary Bayer, Michael Dietrich, Torsten Lowin

J Neuroinflammation· October 2025

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Cannabidiol: Influence on B Cells, Peripheral Blood Mononuclear Cells, and Peripheral Blood Mononuclear Cell/Rheumatoid Arthritis Synovial Fibroblast Cocultures.
Torsten Lowin, Sofia Anna Laaser, Christina Kok, Eileen Bruneau, Georg Pongratz

Cannabis Cannabinoid Res· April 2023

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Components of the sympathetic nervous system as targets to modulate inflammation - rheumatoid arthritis synovial fibroblasts as neuron-like cells?
Xinkun Cheng, Torsten Lowin, Nadine Honke, Georg Pongratz

J Inflamm (Lond)· March 2023

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Anti-Inflammatory Effects of Cannabigerol in Rheumatoid Arthritis Synovial Fibroblasts and Peripheral Blood Mononuclear Cell Cultures Are Partly Mediated by TRPA1.
Torsten Lowin, Marianne Sofia Tigges-Perez, Eva Constant, Georg Pongratz

Int J Mol Sci· January 2023

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Impact of Δ-Tetrahydrocannabinol on Rheumatoid Arthritis Synovial Fibroblasts Alone and in Co-Culture with Peripheral Blood Mononuclear Cells.
Torsten Lowin, Christina Kok, Sophie Smutny, Georg Pongratz

Biomedicines· May 2022

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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells.
Nadine Honke, Torsten Lowin, Birgit Opgenoorth, Namir Shaabani, Alexander Lautwein

PLoS Biol· January 2022

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Characterization of B- and T-Cell Compartment and B-Cell Related Factors Belonging to the TNF/TNFR Superfamily in Patients With Clinically Active Systemic Lupus Erythematosus: Baseline BAFF Serum Levels Are the Strongest Predictor of Response to Belimumab after Twelve Months of Therapy.
Silvia Piantoni, Francesca Regola, Stefania Masneri, Michele Merletti, Torsten Lowin

Front Pharmacol· May 2021

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Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts.
Torsten Lowin, Ren Tingting, Julia Zurmahr, Tim Classen, Matthias Schneider

Cell Death Dis· September 2020

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Positive and negative cooperativity of TNF and Interferon-γ in regulating synovial fibroblast function and B cell survival in fibroblast/B cell co-cultures.
Torsten Lowin, Tareq M Anssar, Marina Bäuml, Tim Classen, Matthias Schneider

Sci Rep· January 2020

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A thyroid hormone network exists in synovial fibroblasts of rheumatoid arthritis and osteoarthritis patients.
Anna-Sophia Pörings, Torsten Lowin, Bianca Dufner, Joachim Grifka, Rainer H Straub

Sci Rep· September 2019

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Comprehensive Longitudinal Surveillance of the IgG Autoantibody Repertoire in Established Systemic Lupus Erythematosus.
Stefan Vordenbäumen, Ralph Brinks, Annika Hoyer, Rebecca Fischer-Betz, Georg Pongratz, Torsten Lowin

Arthritis Rheumatol· May 2019

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Tryptophan metabolism in rheumatoid arthritis is associated with rheumatoid factor and predicts joint pathology evaluated by the Rheumatoid Arthritis MRI Score (RAMRIS).
Georg Pongratz, Torsten Lowin, Philipp Sewerin, Frank Zaucke, Zsuzsa Jenei-Lanzl

Clin Exp Rheumatol· May 2019

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Joints for joints: cannabinoids in the treatment of rheumatoid arthritis.
Torsten Lowin, Matthias Schneider, Georg Pongratz

Curr Opin Rheumatol· May 2019

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Association Between Changes in BLyS Levels and the Composition of B and T Cell Compartments in Patients With Refractory Systemic Lupus Erythematosus Treated With Belimumab.
Francesca Regola, Silvia Piantoni, Torsten Lowin, Silvia Archetti, Rossella Reggia

Front Pharmacol· April 2019

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Selective killing of proinflammatory synovial fibroblasts via activation of transient receptor potential ankyrin (TRPA1).
Torsten Lowin, Janna Bleck, Matthias Schneider, Georg Pongratz

Biochem Pharmacol· August 2018

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α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients.
Markus Böhm, Mara Apel, Torsten Lowin, Julia Lorenz, Zsuzsa Jenei-Lanzl

Biochem Pharmacol· September 2016

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Synovial fibroblasts integrate inflammatory and neuroendocrine stimuli to drive rheumatoid arthritis.
Torsten Lowin, Rainer H Straub

Expert Rev Clin Immunol· June 2016

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Peripheral elimination of the sympathetic nervous system stimulates immunocyte retention in lymph nodes and ameliorates collagen type II arthritis.
Susanne Klatt, Hubert Stangl, Julia Kunath, Torsten Lowin, Georg Pongratz

Brain Behav Immun· May 2016

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The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets.
Torsten Lowin, Georg Pongratz, Rainer H Straub

J Inflamm (Lond)· May 2016

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Proinflammatory receptor switch from Gαs to Gαi signaling by β-arrestin-mediated PDE4 recruitment in mixed RA synovial cells.
Zsuzsa Jenei-Lanzl, Janika Zwingenberg, Torsten Lowin, Sven Anders, Rainer H Straub

Brain Behav Immun· November 2015

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Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.
Torsten Lowin, Martin Apitz, Sven Anders, Rainer H Straub

Arthritis Res Ther· November 2015

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Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis.
Torsten Lowin, Rainer H Straub

Arthritis Res Ther· September 2015

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A sustained high fat diet for two years decreases IgM and IL-1 beta in ageing Wistar rats.
Georg Pongratz, Torsten Lowin, Robert Kob, Roland Buettner, Thomas Bertsch

Immun Ageing· September 2015

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Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis.
Zsuzsa Jenei-Lanzl, Silvia Capellino, Frieder Kees, Martin Fleck, Torsten Lowin

Ann Rheum Dis· February 2015

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Increased expression of dopamine receptors in synovial fibroblasts from patients with rheumatoid arthritis: inhibitory effects of dopamine on interleukin-8 and interleukin-6.
Silvia Capellino, Marco Cosentino, Alessandra Luini, Raffaella Bombelli, Torsten Lowin

Arthritis Rheumatol· October 2014

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