Publications by authors named "Torsten Olszak"

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CCL20 expression is elevated in inflammatory bowel disease and attenuated by vitamin D metabolites.
Johannes Stallhofer, Felix Reichl, Michael Lauseker, Lisa Waldenmaier, Helga Paula Török, Torsten Olszak

Sci Rep· June 2025

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Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression.
Johannes Stallhofer, Lisa Veith, Julia Diegelmann, Philipp Probst, Stephan Brand, Torsten Olszak

Clin Transl Gastroenterol· January 2022

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Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
Fabian Schnitzler, Matthias Friedrich, Marianne Angelberger, Julia Diegelmann, Johannes Stallhofer, Torsten Olszak

PLoS One· September 2020

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CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation.
Sebastian Zeissig, Kenneth Peuker, Shankar Iyer, Thomas Gensollen, Stephanie K Dougan, Torsten Olszak

Proc Natl Acad Sci U S A· September 2017

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Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort.
Fabian Schnitzler, Matthias Friedrich, Johannes Stallhofer, Ulf Schönermarck, Michael Fischereder, Torsten Olszak

PLoS One· May 2016

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The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A>C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations.
Fabian Schnitzler, Matthias Friedrich, Christiane Wolf, Johannes Stallhofer, Marianne Angelberger, Torsten Olszak

PLoS One· March 2016

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The NOD2 p.Leu1007fsX1008 mutation (rs2066847) is a stronger predictor of the clinical course of Crohn's disease than the FOXO3A intron variant rs12212067.
Fabian Schnitzler, Matthias Friedrich, Christiane Wolf, Marianne Angelberger, Julia Diegelmann, Torsten Olszak

PLoS One· August 2015

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Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.
Julia Diegelmann, Darina Czamara, Emmanuelle Le Bras, Eva Zimmermann, Torsten Olszak

PLoS One· August 2014

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Involvement of the iNKT cell pathway is associated with early-onset eosinophilic esophagitis and response to allergen avoidance therapy.
Willem S Lexmond, Joana F Neves, Samuel Nurko, Torsten Olszak, Mark A Exley

Am J Gastroenterol· May 2014

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Protective mucosal immunity mediated by epithelial CD1d and IL-10.
Torsten Olszak, Joana F Neves, C Marie Dowds, Kristi Baker, Jonathan Glickman

Nature· May 2014

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Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells.
Dingding An, Sungwhan F Oh, Torsten Olszak, Joana F Neves, Fikri Y Avci

Cell· January 2014

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CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
Shuhei Hosomi, Zhangguo Chen, Kristi Baker, Lanfen Chen, Yu-Hwa Huang, Torsten Olszak

Eur J Immunol· September 2013

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IRGM variants and susceptibility to inflammatory bowel disease in the German population.
Jürgen Glas, Julia Seiderer, Stephanie Bues, Johannes Stallhofer, Christoph Fries, Torsten Olszak

PLoS One· July 2013

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PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.
Jürgen Glas, Julia Seiderer, Darina Czamara, Giulia Pasciuto, Julia Diegelmann, Torsten Olszak

PLoS One· June 2013

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Analyzing antigen recognition by Natural Killer T cells.
Sebastian Zeissig, Torsten Olszak, Espen Melum, Richard S Blumberg

Methods Mol Biol· June 2013

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PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.
Jürgen Glas, Johanna Wagner, Julia Seiderer, Torsten Olszak, Martin Wetzke

PLoS One· August 2012

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Analysis of IL12B gene variants in inflammatory bowel disease.
Jürgen Glas, Julia Seiderer, Johanna Wagner, Torsten Olszak, Christoph Fries

PLoS One· July 2012

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The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.
Jürgen Glas, Julia Seiderer, Corinna Bayrle, Martin Wetzke, Christoph Fries, Torsten Olszak

PLoS One· May 2012

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Microbial exposure during early life has persistent effects on natural killer T cell function.
Torsten Olszak, Dingding An, Sebastian Zeissig, Miguel Pinilla Vera, Julia Richter

Science· April 2012

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A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory proteins.
Julia Diegelmann, Torsten Olszak, Burkhard Göke, Richard S Blumberg, Stephan Brand

J Biol Chem· January 2012

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CEACAM1 dampens antitumor immunity by down-regulating NKG2D ligand expression on tumor cells.
Zhangguo Chen, Lanfen Chen, Kristi Baker, Torsten Olszak, Sebastian Zeissig

J Exp Med· December 2011

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Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.
Laura E Fredenburgh, Margarita M Suárez Velandia, Jun Ma, Torsten Olszak, Manuela Cernadas

J Immunol· November 2011

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Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.
Jürgen Glas, Julia Seiderer, Daniel Fischer, Barbara Tengler, Simone Pfennig, Torsten Olszak

Inflamm Bowel Dis· September 2011

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CEACAM6 gene variants in inflammatory bowel disease.
Jürgen Glas, Julia Seiderer, Christoph Fries, Cornelia Tillack, Simone Pfennig, Torsten Olszak

PLoS One· April 2011

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The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.
Jürgen Glas, Julia Seiderer, Cornelia Tillack, Simone Pfennig, Florian Beigel, Torsten Olszak

PLoS One· December 2010

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