Publications by authors named "Toru Esaki"

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Synthesis and Biological Evaluations of Novel Human Parathyroid Hormone 1 Receptor (hPTHR1) Agonists Bearing Bicyclic Aromatic Moiety.
Yoshikazu Nishimura, Toru Esaki, Yoshiaki Isshiki, Yoshiyuki Furuta, Takashi Emura

ChemMedChem· March 2024

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[Supplementing a Web-based Exposure Estimation System with Deep Learning for Automatic Classification of CT Images to Increase the Efficiency of Effective Dose Estimation].
Toru Esaki

Nihon Hoshasen Gijutsu Gakkai Zasshi· April 2022

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[Automation of Damage Detection and Damage Area Measurement of X-ray Protective Clothing Using Deep Learning].
Toru Esaki, Hiroaki Ishihara

Nihon Hoshasen Gijutsu Gakkai Zasshi· October 2021

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[Supplementing a Web-based Exposure Estimation System with Deep Learning for Automatic Classification of CT Images to Increase the Efficiency of Effective Dose Estimation].
Toru Esaki, Tomoaki Kawashima

Nihon Hoshasen Gijutsu Gakkai Zasshi· November 2020

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[Volume Measurements of Post-transplanted Liver of Pediatric Recipients Using Workstations and Deep Learning].
Toru Esaki, Rieko Furukawa

Nihon Hoshasen Gijutsu Gakkai Zasshi· November 2020

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Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective, and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist.
Yoshikazu Nishimura, Toru Esaki, Yoshiaki Isshiki, Yoshiyuki Furuta, Akemi Mizutani

J Med Chem· May 2020

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Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small Molecule for Treatment of Hypoparathyroidism.
Yoshikazu Nishimura, Toru Esaki, Yoshiaki Isshiki, Naoki Okamoto, Yoshiyuki Furuta

J Med Chem· July 2018

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Efficient asymmetric synthesis of novel gastrin receptor antagonist AG-041R via highly stereoselective alkylation of oxindole enolates.
Takashi Emura, Toru Esaki, Kazutaka Tachibana, Makoto Shimizu

J Org Chem· October 2006

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Structure-based design of P3 moieties in the peptide mimetic factor VIIa inhibitor.
Shojiro Kadono, Akihisa Sakamoto, Yasufumi Kikuchi, Masayoshi Oh-eda, Naohiro Yabuta, Toru Esaki

Biochem Biophys Res Commun· February 2005

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Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4.
Shojiro Kadono, Akihisa Sakamoto, Yasufumi Kikuchi, Masayoshi Oh-Eda, Naohiro Yabuta, Toru Esaki

Acta Crystallogr Sect F Struct Biol Cryst Commun· February 2005

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Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor.
Shojiro Kadono, Akihisa Sakamoto, Yasufumi Kikuchi, Masayoshi Oh-Eda, Naohiro Yabuta, Toru Esaki

Biochem Biophys Res Commun· January 2005

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Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor.
Shojiro Kadono, Akihisa Sakamoto, Yasufumi Kikuchi, Masayoshi Oh-eda, Naohiro Yabuta, Toru Esaki

Biochem Biophys Res Commun· November 2004

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