Publications by authors named "Toru Horie"

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[A study on the competencies of public health doctors responding to international and domestic public health administration: Insights from interviews].
Haruka Sato, Akihiro Hosono, Ichiro Kadouchi, Toru Horie, Akira Sudo

Nihon Koshu Eisei Zasshi· September 2025

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Evaluation of Parent- and Metabolite-Induced Mitochondrial Toxicities Using CYP-Introduced HepG2 cells.
Akinori Takemura, Simin Gong, Tomoyuki Sato, Moemi Kawaguchi, Shuichi Sekine, Toru Horie

J Pharm Sci· September 2021

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Non-invasive Measurement of Skin Autofluorescence as a Beneficial Surrogate Marker for Atherosclerosis in Patients with Type 2 Diabetes.
Jin Temma, Munehide Matsuhisa, Toru Horie, Akio Kuroda, Hiroyasu Mori

J Med Invest· January 2017

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Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry.
Hiroshi Yamazaki, Hiroshi Suemizu, Yasuhiro Kazuki, Ken Oofusa, Shunji Kuribayashi, Toru Horie

Chem Res Toxicol· August 2016

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Predictability of plasma concentration-time curves in humans using single-species allometric scaling of chimeric mice with humanized liver.
Seigo Sanoh, Yoichi Naritomi, Mami Fujimoto, Koya Sato, Akio Kawamura, Toru Horie

Xenobiotica· April 2016

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Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates.
Seigo Sanoh, Masataka Santoh, Masashi Takagi, Tatsuya Kanayama, Kazumi Sugihara, Toru Horie

Toxicol In Vitro· September 2014

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Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MS.
Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Toru Horie

Drug Metab Dispos· June 2014

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Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes.
Chiaki Tanoue, Kazumi Sugihara, Naoto Uramaru, Yoshitaka Tayama, Yoko Watanabe, Toru Horie

Xenobiotica· November 2013

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Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes.
Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Toru Horie

Drug Metab Dispos· December 2012

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Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese.
Minako Hijikata, Junko Shojima, Ikumi Matsushita, Katsushi Tokunaga, Jun Ohashi, Toru Horie

Hum Genet· May 2012

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Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Toru Horie

Drug Metab Dispos· February 2012

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Expression levels of drug-metabolizing enzyme, transporter, and nuclear receptor mRNAs in a novel three-dimensional culture system for human hepatocytes using micro-space plates.
Masuhiro Nishimura, Yoko Ejiri, Sanae Kishimoto, Satoshi Suzuki, Tetsuo Satoh, Toru Horie

Drug Metab Pharmacokinet· September 2011

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Secretion of albumin and induction of CYP1A2 and CYP3A4 in novel three-dimensional culture system for human hepatocytes using micro-space plate.
Masuhiro Nishimura, Mieko Hagi, Yoko Ejiri, Sanae Kishimoto, Toru Horie

Drug Metab Pharmacokinet· October 2010

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Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity: a comparative study in humans and rodents including chimeric mice carrying human liver.
Arief Nurrochmad, Yuji Ishii, Hitomi Nakanoh, Tae Inoue, Toru Horie

Drug Metab Pharmacokinet· October 2010

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A study of the effect of the femoral head diameter on prosthetic hip joint dislocation using a hip-joint motion simulator.
Kazuo Kiguchi, Toru Horie, Akira Yamashita, Masaru Ueno, Tsuneyuki Kobayashi

Annu Int Conf IEEE Eng Med Biol Soc· April 2010

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Approach for in vivo protein binding of 5-n-butyl-pyrazolo[1,5-a]pyrimidine bioactivated in chimeric mice with humanized liver by two-dimensional electrophoresis with accelerator mass spectrometry.
Hiroshi Yamazaki, Shunji Kuribayashi, Tae Inoue, Chise Tateno, Yasufumi Nishikura, Toru Horie

Chem Res Toxicol· January 2010

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Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.
Tae Inoue, Kazumi Sugihara, Hiroki Ohshita, Toru Horie, Shigeyuki Kitamura

Drug Metab Pharmacokinet· November 2009

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Influence of tumor peroxisome proliferator-activated receptor gamma and delta expression on postoperative mortality of patients undergoing colorectal cancer surgery.
Mitsuru Ishizuka, Tokihiko Sawada, Toshie Okada, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie

J Invest Surg· May 2009

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POSSUM is an optimal system for predicting mortality due to colorectal perforation.
Mitsuru Ishizuka, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie, Keiichi Kubota

Hepatogastroenterology· December 2008

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CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
Tae Inoue, Kayoko Nitta, Kazumi Sugihara, Toru Horie, Shigeyuki Kitamura

Drug Metab Dispos· December 2008

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Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.
Shigeyuki Kitamura, Kayoko Nitta, Yoshitaka Tayama, Chiaki Tanoue, Kazumi Sugihara, Toru Horie

Drug Metab Dispos· July 2008

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Usefulness of Groshong catheters for central venous access via the external jugular vein.
Mitsuru Ishizuka, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie, Tokihiko Sawada

J Invest Surg· April 2008

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External jugular Groshong catheter is associated with fewer complications than a subclavian Argyle catheter.
Mitsuru Ishizuka, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie, Makoto Furihata

Eur Surg Res· March 2008

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Inflammation-based prognostic score is a novel predictor of postoperative outcome in patients with colorectal cancer.
Mitsuru Ishizuka, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie, Keiichi Kubota

Ann Surg· December 2007

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Rectal angiolipoma diagnosed after surgical resection: a case report.
Mitsuru Ishizuka, Hitoshi Nagata, Kazutoshi Takagi, Toru Horie, Akihito Abe

World J Gastroenterol· January 2007

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