Publications by authors named "Toshihide Shima"

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Association Between Liver Fibrosis and Cause-Specific Mortality in Japanese Patients With Biopsy-Confirmed Metabolic Dysfunction-Associated Steatotic Liver Disease: A Prospective Cohort Study / Liver Fibrosis and Mortality in Japanese MASLD.
Kyoko Sakai, Toshihide Shima, Hirohisa Oya, Takahiro Miura, Shohei Amioka

Hepatol Res· January 2026

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Variations in Estimated Glomerular Filtration Rate Across Countries in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease and Their Association With Liver Fibrosis: A Multicenter Study.
Jing Zhao, Ferenc E Mózes, Xin-Yu Xu, Dong Ji, Huiqing Liang, Toshihide Shima

MedComm (2020)· December 2025

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A novel scoring system to identify patients at low risk for hepatocellular carcinoma five years after DAA-Induced sustained virological response: a retrospective cohort study.
Hideki Fujii, Takeshi Nishimura, Hiroyuki Kimura, Yasuhide Mitsumoto, Toshihide Shima

BMC Gastroenterol· November 2025

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[A case of rectal varices with recurrent hepatic encephalopathy successfully treated with percutaneous embolization].
Shohei Amioka, Kohei Fukumoto, Yasuhide Mitsumoto, Keiichiro Okuda, Kei Terasaki, Toshihide Shima

Nihon Shokakibyo Gakkai Zasshi· May 2025

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acFibroMASH Index for the Diagnosis of Fibrotic MASH and Prediction of Liver-related Events: An International Multicenter Study.
Gong Feng, Ferenc E Mózes, Dong Ji, Sombat Treeprasertsuk, Takeshi Okanoue, Toshihide Shima

Clin Gastroenterol Hepatol· April 2025

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Clinical Utility of Genetic Variants in PNPLA3 and TM6SF2 to Predict Liver-Related Events in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Yuya Seko, Kanji Yamaguchi, Toshihide Shima, Michihiro Iwaki, Hirokazu Takahashi

Liver Int· April 2025

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Accuracy of type IV collagen 7S versus Enhanced Liver Fibrosis score for diagnosing fibrosis in patients with metabolic dysfunction-associated steatotic liver disease.
Hiroshi Ishiba, Hideki Fujii, Yoshihiro Kamada, Yoshio Sumida, Hirokazu Takahashi, Toshihide Shima, Hideaki Fukushima, Shinichi Aishima

Hepatol Commun· January 2025

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Prognostic performance of a two-step method using the Fibro-Scope system for metabolic dysfunction-associated steatotic liver disease.
Yuya Seko, Kanji Yamaguchi, Toshihide Shima, Saiyu Tanaka, Takao Shirono

Hepatol Res· October 2024

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Diagnostic accuracy of non-invasive tests to screen for at-risk MASH-An individual participant data meta-analysis.
Ferenc E Mózes, Jenny A Lee, Yasaman Vali, Emmanuel A Selvaraj, Arjun N A Jayaswal, Toshihide Shima

Liver Int· August 2024

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Differential Effects of Genetic Polymorphism on Comorbid Disease in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Yuya Seko, Kanji Yamaguchi, Toshihide Shima, Michihiro Iwaki, Hirokazu Takahashi

Clin Gastroenterol Hepatol· July 2024

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Accuracy of the Enhanced Liver Fibrosis Test in Patients With Type 2 Diabetes Mellitus and Its Clinical Implications.
Taeang Arai, Hirokazu Takahashi, Yuya Seko, Hidenori Toyoda, Hideki Hayashi, Toshihide Shima, Hideaki Fukushima, Shinichi Aishima

Clin Gastroenterol Hepatol· April 2024

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Impact of fibrosis on liver-related event incidence in nonalcoholic fatty liver disease: A multicenter observational study.
Kazuaki Chayama, Akira Hiramatsu, Toshihide Shima, Yoshito Itoh, Kanji Yamaguchi

Hepatol Res· December 2023

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Artificial intelligence/neural network system that accurately diagnoses hepatocellular carcinoma in nonalcoholic steatohepatitis.
Takeshi Okanoue, Kanji Yamaguchi, Toshihide Shima, Yasuhide Mitsumoto, Takayuki Katayama

Hepatol Res· December 2023

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The greater impact of PNPLA3 polymorphism on liver-related events in Japanese non-alcoholic fatty liver disease patients: A multicentre cohort study.
Yuya Seko, Kanji Yamaguchi, Toshihide Shima, Michihiro Iwaki, Hirokazu Takahashi

Liver Int· October 2023

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Impact of a Novel Digital Therapeutics System on Nonalcoholic Steatohepatitis: The NASH App Clinical Trial.
Masaya Sato, Masatoshi Akamatsu, Toshihide Shima, Tadashi Ikegami, Mikio Yanase

Am J Gastroenterol· August 2023

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Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis.
Ferenc E Mózes, Jenny A Lee, Yasaman Vali, Osama Alzoubi, Katharina Staufer, Toshihide Shima

Lancet Gastroenterol Hepatol· August 2023

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Fibro-Scope V1.0.1: an artificial intelligence/neural network system for staging of nonalcoholic steatohepatitis.
Kanji Yamaguchi, Toshihide Shima, Yasuhide Mitsumoto, Yuya Seko, Atsushi Umemura

Hepatol Int· June 2023

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Validation of the utility of Agile scores to identify advanced fibrosis and cirrhosis in Japanese patients with nonalcoholic fatty liver disease.
Satoshi Oeda, Yuya Seko, Hideki Hayashi, Taeang Arai, Michihiro Iwaki, Toshihide Shima, Hideaki Fukushima, Shinichi Aishima

Hepatol Res· June 2023

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Diagnostic accuracy of enhanced liver fibrosis test for nonalcoholic steatohepatitis-related fibrosis: Multicenter study.
Yuya Seko, Hirokazu Takahashi, Hidenori Toyoda, Hideki Hayashi, Kanji Yamaguchi, Toshihide Shima, Hideaki Fukushima, Shinichi Aishima

Hepatol Res· April 2023

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Serum levels of immunoglobulin M-free inhibitors of macrophage/CD5L as a predictive and early diagnostic marker for nonalcoholic steatohepatitis-associated hepatocellular carcinoma.
Takeshi Okanoue, Kanji Yamaguchi, Toshihide Shima, Yasuhide Mitsumoto, Masayuki Mizuno

Hepatol Res· December 2022

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Misunderstanding of hepatitis C virus (HCV) infection status by non-specialized medical doctors in patients who achieved sustained virologic response to anti-HCV therapy.
Hidenori Toyoda, Satoshi Yasuda, Akio Moriya, Ei Itobayashi, Haruki Uojima, Toshihide Shima

J Infect Chemother· September 2022

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Comparison of thrombocytopenia between patients with non-alcoholic fatty liver disease and those with hepatitis C virus-related chronic liver disease.
Naohiko Kinoshita, Toshihide Shima, Kei Terasaki, Hirohisa Oya, Takayuki Katayama

Hepatol Res· August 2022

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Time-course changes in liver functional reserve after successful sofosbuvir/velpatasvir treatment in patients with decompensated cirrhosis.
Masanori Atsukawa, Akihito Tsubota, Chisa Kondo, Hidenori Toyoda, Makoto Nakamuta, Toshihide Shima, Noritomo Shimada

Hepatol Res· March 2022

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Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-β1/SMAD Signaling and Autophagy in Hepatic Stellate Cells.
Seita Kataoka, Atsushi Umemura, Keiichiro Okuda, Hiroyoshi Taketani, Yuya Seko, Toshihide Shima

Int J Mol Sci· December 2021

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Enhanced Antitumor Effect in Liver Cancer by Amino Acid Depletion-Induced Oxidative Stress.
Keiichiro Okuda, Atsushi Umemura, Seita Kataoka, Kota Yano, Aya Takahashi, Toshihide Shima

Front Oncol· November 2021

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