Publications by authors named "Toshio Kitamura"

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Prospective isolation of mouse and human hematopoietic stem cells using PLXDC2.
Yosuke Tanaka, Yasushi Kubota, Riko Kikuchi, Tomohiro Yabushita, Takaharu Kimura, Toshio Kitamura

Commun Biol· December 2025

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Machine Learning-Based Predictive Modeling Maximizes the Efficacy of mTOR/p53 Co-Targeting Therapy Against AML.
Jingmei Li, Emi Sugimoto, Keita Yamamoto, Yutong Dai, Wenyu Zhang, Toshio Kitamura

Cancer Sci· November 2025

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Breakdown of blood-brain barrier, astrocytic endfeet swelling, and abnormal behaviors by blockade of TROY signaling in TROY-Fc transgenic mice.
Tadasuke Komori, Tomoko Hisaoka, Emi Kuriyama, Mizuki Kajimoto, Naoyuki Nakao, Toshio Kitamura

Brain Behav Immun· November 2025

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ASXL1 mutation-related clonal hematopoiesis and age-related diseases: clinical evidence and molecular insights.
Naru Sato, Susumu Goyama, Toshio Kitamura

Int J Hematol· September 2025

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Sampling and metabarcoding of arthropod environmental DNA traces from flowers.
David Wari, Yoshinobu Kusumoto, Toshio Kitamura

MethodsX· June 2025

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Native Japanese Polygonaceae Species as Potential Native Insectary Plants in Conserving Indigenous Natural Enemies.
David Wari, Junichiro Abe, Toshio Kitamura

Insects· February 2025

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NPM1-fusion proteins promote myeloid leukemogenesis through XPO1-dependent HOX activation.
Yuko Shimosato, Keita Yamamoto, Yuhan Jia, Wenyu Zhang, Norio Shiba, Toshio Kitamura

Leukemia· January 2025

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HDAC7 is a potential therapeutic target in acute erythroid leukemia.
Wenyu Zhang, Keita Yamamoto, Yu-Hsuan Chang, Tomohiro Yabushita, Yangying Hao, Toshio Kitamura

Leukemia· December 2024

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Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA.
Kazutaka Murayama, Miyuki Kato-Murayama, Toshiaki Hosaka, Toshio Kitamura, Shigeyuki Yokoyama

J Struct Biol· December 2024

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Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunity.
Naru Sato, Susumu Goyama, Yu-Hsuan Chang, Masashi Miyawaki, Takeshi Fujino, Toshio Kitamura

Nat Cardiovasc Res· December 2024

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Prostaglandin E-EP2/EP4 signaling induces immunosuppression in human cancer by impairing bioenergetics and ribosome biogenesis in immune cells.
Siwakorn Punyawatthananukool, Ryuma Matsuura, Thamrong Wongchang, Nao Katsurada, Tatsuaki Tsuruyama, Toshio Kitamura

Nat Commun· November 2024

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SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation.
Yu-Hsuan Chang, Keita Yamamoto, Takeshi Fujino, Teh-Wei Wang, Emi Sugimoto, Toshio Kitamura

Cell Rep· August 2024

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[Molecular mechanism of DNA hypomethylating agents in myeloid tumors].
Tomohiro Yabushita, Toshio Kitamura, Susumu Goyama

Rinsho Ketsueki· April 2024

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BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state.
Muran Xiao, Shinji Kondo, Masaki Nomura, Shinichiro Kato, Koutarou Nishimura, Toshio Kitamura

Nat Commun· December 2023

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Hyperactive Natural Killer cells in Rag2 knockout mice inhibit the development of acute myeloid leukemia.
Emi Sugimoto, Jingmei Li, Yasutaka Hayashi, Kohei Iida, Shuhei Asada, Toshio Kitamura

Commun Biol· December 2023

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The E3 ligase DTX2 inhibits RUNX1 function by binding its C terminus and prevents the growth of RUNX1-dependent leukemia cells.
Taishi Yonezawa, Hirotaka Takahashi, Yangying Hao, Chie Furukawa, Akiho Tsuchiya, Toshio Kitamura

FEBS J· November 2023

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Identification of compounds that preferentially suppress the growth of T-cell acute lymphoblastic leukemia-derived cells.
Kazuya Miyashita, Takuya Yagi, Noritaka Kagaya, Azusa Takechi, Chihiro Nakata, Toshio Kitamura

Cancer Sci· October 2023

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[Novel therapeutic strategy for targeting chronic myeloid leukemia stem cells via IRAK1/4 inhibition].
Yosuke Tanaka, Toshio Kitamura

Rinsho Ketsueki· October 2023

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TLR7/8 stress response drives histiocytosis in SLC29A3 disorders.
Takuma Shibata, Ryota Sato, Masato Taoka, Shin-Ichiroh Saitoh, Mayumi Komine, Toshio Kitamura

J Exp Med· September 2023

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SETBP1 is dispensable for normal and malignant hematopoiesis.
Atsushi Tanaka, Koutarou Nishimura, Wataru Saika, Ayana Kon, Yui Koike, Toshio Kitamura

Leukemia· September 2023

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Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment.
Tomohiro Yabushita, Takumi Chinen, Atsuya Nishiyama, Shuhei Asada, Ruka Shimura, Toshio Kitamura

Cell Rep· September 2023

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IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia.
Xiaoxiao Liu, Naru Sato, Tomohiro Yabushita, Jingmei Li, Yuhan Jia, Toshio Kitamura

EMBO Mol Med· January 2023

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Mechanisms involved in hematopoietic stem cell aging.
Takeshi Fujino, Shuhei Asada, Susumu Goyama, Toshio Kitamura

Cell Mol Life Sci· August 2022

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Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Toshio Kitamura

Nat Commun· August 2022

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Changes in the proportion of anemia among young women after the Great East Japan Earthquake: the Fukushima health management survey.
Kana Yamamoto, Morihito Takita, Masahiro Kami, Yoshinobu Takemoto, Tetsuya Ohira, Toshio Kitamura

Sci Rep· June 2022

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