Publications by authors named "Toshiya Inaba"

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Utility of the Base Editing System for Introducing Drug-Resistant Gene Mutations Into Human Leukemia Cellular Models.
Thao Nguyen, Minori Tamai, Shinichi Fujisawa, Akiko Nagamachi, Keiko Kagami, Toshiya Inaba

Cureus· April 2025

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Application of prime editing system to introduce TP53 R248Q hotspot mutation in acute lymphoblastic leukemia cell line.
Thao Nguyen, Tomomi Aida, Yuka Iijima-Yamashita, Minori Tamai, Akiko Nagamachi, Toshiya Inaba

Cancer Sci· June 2024

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Tumour-derived exosomes promote the induction of monocytic myeloid-derived suppressor cells from peripheral blood mononuclear cells by delivering miR-106a-5p and miR-146a-5p in multiple myeloma.
Kentaro Mizuhara, Yuji Shimura, Taku Tsukamoto, Akinori Kanai, Saeko Kuwahara-Ota, Toshiya Inaba

Br J Haematol· November 2023

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A novel anticancer quinolone, (R)-WAC-224, has anti-leukemia activities against acute myeloid leukemia.
Tatsuji Mino, Hiroshi Ureshino, Taichi Ueshima, Naoki Kashimoto, Tomonori Yamaguchi, Toshiya Inaba

Invest New Drugs· October 2023

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Ribosome profiling analysis reveals the roles of DDX41 in translational regulation.
Saruul Tungalag, Satoru Shinriki, Mayumi Hirayama, Akiko Nagamachi, Akinori Kanai, Toshiya Inaba

Int J Hematol· June 2023

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MOZ/ENL complex is a recruiting factor of leukemic AF10 fusion proteins.
Yosuke Komata, Akinori Kanai, Takahiro Maeda, Toshiya Inaba, Akihiko Yokoyama

Nat Commun· April 2023

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[Mouse models of hematological diseases using genome editing technology].
Akiko Nagamachi, Toshiya Inaba

Rinsho Ketsueki· December 2022

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DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells.
Satoru Shinriki, Mayumi Hirayama, Akiko Nagamachi, Akihiko Yokoyama, Takeshi Kawamura, Toshiya Inaba

Leukemia· November 2022

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Design, synthesis and biological evaluation of 2-pyrrolone derivatives as radioprotectors.
Hidetoshi Satoh, Shintaro Ochi, Kosuke Mizuno, Yutaka Saga, Shohei Ujita, Toshiya Inaba

Bioorg Med Chem· August 2022

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Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia.
Atsushi Tanaka, Taizo A Nakano, Masaki Nomura, Hiromi Yamazaki, Jan P Bewersdorf, Toshiya Inaba

Blood· August 2022

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Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
Tomoya Isobe, Masatoshi Takagi, Aiko Sato-Otsubo, Akira Nishimura, Genta Nagae, Toshiya Inaba

Nat Commun· August 2022

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Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
Minori Tamai, Shin Kasai, Koshi Akahane, Thao Nguyen Thu, Keiko Kagami, Toshiya Inaba

J Steroid Biochem Mol Biol· April 2022

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A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis.
Akinori Morita, Shintaro Ochi, Hidetoshi Satoh, Shohei Ujita, Yosuke Matsushita, Toshiya Inaba

Life (Basel)· October 2021

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HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis.
Satoshi Takahashi, Akinori Kanai, Hiroshi Okuda, Ryo Miyamoto, Yosuke Komata, Toshiya Inaba

Elife· August 2021

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HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways.
Ryo Miyamoto, Akinori Kanai, Hiroshi Okuda, Yosuke Komata, Satoshi Takahashi, Toshiya Inaba

Elife· July 2021

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Revertant somatic mosaicism as a cause of cancer.
Toshiya Inaba, Akiko Nagamachi

Cancer Sci· April 2021

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UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
Yasuyuki Sera, Yuichiro Nakata, Takeshi Ueda, Norimasa Yamasaki, Shuhei Koide, Toshiya Inaba

Blood· February 2021

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Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes.
Akiko Nagamachi, Akinori Kanai, Megumi Nakamura, Hiroshi Okuda, Akihiko Yokoyama, Toshiya Inaba

J Clin Invest· February 2021

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Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.
Atsushi Watanabe, Kunio Miyake, Jessica Nordlund, Ann-Christine Syvänen, Louise van der Weyden, Toshiya Inaba

Blood· November 2020

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HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
Reina Takeda, Shuhei Asada, Sung-Joon Park, Akihiko Yokoyama, Hans Jiro Becker, Toshiya Inaba

Blood· October 2020

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High prevalence of MEF2D fusion in human B-cell precursor acute lymphoblastic leukemia cell lines.
Koshi Akahane, Takahiko Yasuda, Shinobu Tsuzuki, Fumihiko Hayakawa, Nobutaka Kiyokawa, Toshiya Inaba

Hematol Oncol· October 2020

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Association between low doses of ionizing radiation, administered acutely or chronically, and time to onset of stroke in a rat model.
Norio Takahashi, Munechika Misumi, Hideko Murakami, Yasuharu Niwa, Waka Ohishi, Toshiya Inaba

J Radiat Res· September 2020

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Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.
Ryo Miyamoto, Hiroshi Okuda, Akinori Kanai, Satoshi Takahashi, Takeshi Kawamura, Toshiya Inaba

Cell Rep· September 2020

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Effects of Radiation on Blood Pressure and Body Weight in the Spontaneously Hypertensive Rat Model. Are Radiation Effects on Blood Pressure Affected by Genetic Background?
Norio Takahashi, Munechika Misumi, Yasuharu Niwa, Hideko Murakami, Waka Ohishi, Toshiya Inaba

Radiat Res· June 2020

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Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status.
Raksha Shrestha, Mamiko Sakata-Yanagimoto, Koichiro Maie, Motohiko Oshima, Masatomo Ishihara, Toshiya Inaba

Blood Adv· March 2020

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